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Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
作者:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
Adobe PDF(1387Kb)  |  收藏  |  浏览/下载：254/59  |  提交时间：2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
Synthesis and cytotoxic activity of novel tetrahydrobenzodifuran-imidazolium salt derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 8, 页码: 1808-1814
作者:  Zhang, Chao-Bo;  Liu, Yang;  Liu, Zheng-Fen;  Duan, Sheng-Zu;  Li, Min-Yan;  Chen, Wen;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
Adobe PDF(1192Kb)  |  收藏  |  浏览/下载：625/105  |  提交时间：2017/06/30
Tetrahydrobenzodifurans  Imidazolium Salts  Cytotoxic Activity  Cell Cycle  Apoptosis  
Melodinine V, an antitumor bisindole alkaloid with selective cytotoxicity from Melodinus henryi 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 20, 页码: 4895-4898
作者:  Liu, Ya-Ping;  Yue, Grace Gar-Lee;  Lee, Julia Kin-Ming;  Feng, Tao;  Zhao, Yun-Li;  Li, Yan;  Lau, Clara Bik-San;  Luo, Xiao-Dong
Adobe PDF(1084Kb)  |  收藏  |  浏览/下载：235/61  |  提交时间：2017/01/05
Melodinine v  Bisindole  Inhibited Cell Proliferation  Cell Cycle Arrest  Cellular Apoptosis  Ht-29 Cells  
N-Hydroxyphthalimide exhibits antitumor activity by suppressing mTOR signaling pathway in BT-20 and LoVo cells 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2016, 卷号: 35
作者:  Wang, Min;  Zhou, Ankun;  An, Tao;  Kong, Lingmei;  Yu, Chunlei;  Liu, Jianmei;  Xia, Chengfeng;  Zhou, Hongyu;  Li, Yan
Adobe PDF(1734Kb)  |  收藏  |  浏览/下载：195/30  |  提交时间：2016/06/27
N-hydroxyphthalimide  Mtor  Inhibitor  Cancer  Mitochondrial Apoptosis  
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi;  Li, Yan
浏览  |  Adobe PDF(3014Kb)  |  收藏  |  浏览/下载：280/71  |  提交时间：2015/06/17
Erib  Activity-based Probes  P50  Nf-kappa b Signaling  Apoptosis  
Evollionines A - C, Three New Alkaloids Isolated from the Fruits of Evodia rutaecarpa 期刊论文
HELVETICA CHIMICA ACTA, 2014, 卷号: 97, 期号: 11, 页码: 1481-1486
作者:  Li, Yan-Hong;  He, Juan;  Li, Yan;  Wu, Xing-De;  Peng, Li-Yan;  Du, Ru-Nan;  Cheng, Xiao;  Zhao, Qin-Shi;  Li, Rong-Tao;  Zhao,QS (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  qinshizhao@mail.kib.ac.cn;  rongtaolikm@gmail.com
浏览  |  Adobe PDF(218Kb)  |  收藏  |  浏览/下载：512/160  |  提交时间：2015/01/20
Isolated Major Compounds  Prostate-cancer  In-vitro  Triterpenoids  Proliferation  Glycosides  Apoptosis  Leaf  
Synthesis and cytotoxic activity of novel 1-((indol-3-yl)methyl)-1H-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 21, 页码: 4926-4930
作者:  Xu, Xiao-Liang;  Wang, Jia;  Yu, Chun-Lei;  Chen, Wen;  Li, Ying-Chao;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong;  Li,Y (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Peoples R China.;  liyanb@mail.kib.ac.cn;  zhanghbyd@gmail.com;  xdyang@ynu.edu.cn
Adobe PDF(670Kb)  |  收藏  |  浏览/下载：378/90  |  提交时间：2014/11/25
Indole  Imidazolium Salts  Structure-activity Relationships  Cell Apoptosis  
Identification of two novel inhibitors of mTOR signaling pathway based on high content screening 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 卷号: 72, 期号: 4, 页码: 799-808
作者:  Yan, Juming;  Zhou, Hongyu;  Kong, Lingmei;  Zhang, Jing;  Zhao, Qinshi;  Li, Yan
Adobe PDF(1971Kb)  |  收藏  |  浏览/下载：676/103  |  提交时间：2013/11/12
Mtor Signaling  Inhibitor  High Content Screening  Cancer  Apoptosis  
Two mixed-NH3/amine platinum (II) anticancer complexes featuring a dichloroacetate moiety in the leaving group 期刊论文
SCIENTIFIC REPORTS, 2013, 卷号: 3, 页码: 2464
作者:  Liu, Weiping;  Su, Jia;  Jiang, Jing;  Li, Xingyao;  Ye, Qingsong;  Zhou, Hongyu;  Chen, Jialin;  Li, Yan
浏览  |  Adobe PDF(639Kb)  |  收藏  |  浏览/下载：321/47  |  提交时间：2013/10/16
Cancer-cells  Agents  Apoptosis  Toxicity  Drugs  
Trichothecin Induces Cell Death in NF-kappa B Constitutively Activated Human Cancer Cells via Inhibition of IKK beta Phosphorylation 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 8, 页码: e71333
作者:  Su, Jia;  Zhao, Peiji;  Kong, Lingmei;  Li, Xingyao;  Yan, Juming;  Zeng, Ying;  Li, Yan
Adobe PDF(1124Kb)  |  收藏  |  浏览/下载：314/59  |  提交时间：2013/11/12
Colitis-associated Cancer  Multiple-myeloma Cells  P65 Phosphorylation  Endophytic Fungus  Kinase-activity  Tumor-growth  In-vitro  Pathway  Apoptosis  Inflammation