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Discovery of diverse sesquiterpenoids from Magnolia grandiflora with cytotoxic activities by inducing cell apoptosis 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 106707
作者:  Xu,Shuangyu;  Tang,Yunyan;  Li,Yanan;  Yang,Jue;  Gu,Wei;  Hao,Xiaojiang;  Yuan,Chunmao
Adobe PDF(5040Kb)  |  收藏  |  浏览/下载:11/4  |  提交时间:2024/07/22
Magnolia grandiflora  Sesquiterpenoids  Isolation and structural modification  Cytotoxic activity  Apoptosis  LACTONES  DERIVATIVES  LEAVES  AGENTS  
Design, synthesis, and biological evaluation of artemyrianolide H derivatives as potential antihepatoma agents 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 137, 页码: 106617
作者:  Li,Tian-Ze;  Yang,Xiao-Tong;  Ma,Wen-Jing;  Ma,Yun-Bao;  Li,Feng-Jiao;  Wang,Yong-Cui;  Chen,Ji-Jun
浏览  |  Adobe PDF(9670Kb)  |  收藏  |  浏览/下载:11/3  |  提交时间:2024/07/22
Artemyrianolide H  Germacranolide derivatives  Antihepatoma activity  Apoptosis  DIMERS  
Oligomeric phloroglucinols with hAChE inhibitory and antibacterial activities from tropic Rhodomyrtus tomentosa 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 106836
作者:  Luo,E-E;  Liu,Si-Na;  Wang,Zhao-Jie;  Chen,Ling-Yun;  Liang,Cheng-Qin;  Yu,Mu-Yuan;  Qin,Xu-Jie
浏览  |  Adobe PDF(3972Kb)  |  收藏  |  浏览/下载:9/3  |  提交时间:2024/07/22
Rhodomyrtus tomentosa  Oligomeric phloroglucinols  h AChE inhibitors  Molecular docking  Antibacterial effects  MYRTUCOMMULONE  DERIVATIVES  ACYLPHLOROGLUCINOLS  MYRTUCOMMUACETALONE  LEAVES  
Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin;  Zuo,Zhili
浏览  |  Adobe PDF(5035Kb)  |  收藏  |  浏览/下载:22/5  |  提交时间:2024/07/22
Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION  
Synthesis of nigranoic acid and manwuweizic acid derivatives as HDAC inhibitors and anti-inflammatory agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 109, 页码: 104728
作者:  Ni,Dong-Xuan;  Wang,Qi;  Li,Yi-Ming;  Cui,Yi-Man;  Shen,Tian-Ze;  Li,Xiao-Li;  Sun,Han-Dong;  Zhang,Xing-Jie;  Zhang,Ruihan;  Xiao,Wei-Lie
收藏  |  浏览/下载:73/0  |  提交时间:2022/04/02
Natural products modification  HDAC inhibition  Inflammasome  Triterpenoid  SCHISANDRA-PROPINQUA  TRITERPENOIDS  MECHANISM  INJURY  
Steroidal saponins with cytotoxic effects from the rhizomes of Asparagus cochinchinensis 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 105237
作者:  Liu,Bo;  Li,Bingxin;  Zhou,Di;  Wen,Xiaoyan;  Wang,Yajun;  Chen,Gang;  Li,Ning
收藏  |  浏览/下载:70/0  |  提交时间:2022/04/02
Asparagus cochinchinensis  Steroidal  NCI-H460 cell line  Cytotoxic  Apoptosis  GLYCOSIDES  CELL  CANCER  
Artemicapillasins A-N, cytotoxic coumaric acid analogues against hepatic stellate cell LX2 from Artemisia capillaris (Yin-Chen) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 117, 页码: 105441
作者:  Gao,Zhen;  Huang,Xiao-Yan;  Geng,Chang-An;  Li,Tian-Ze;  Chen,Ji-Jun
浏览  |  Adobe PDF(1872Kb)  |  收藏  |  浏览/下载:135/43  |  提交时间:2022/04/02
Artemisia capillaris  Coumaric acid analogues  Antihepatic fibrosis effects  HSC-LX2  Extracellular matrix  TRADITIONAL CHINESE HERB  ACTIVE CONSTITUENTS  LIVER FIBROSIS  
Functional triterpenoids from medicinal fungi Ganoderma applanatum: A continuous search for antiadipogenic agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104977
作者:  Su,Hai-Guo;  Wang,Qian;  Zhou,Lin;  Peng,Xing-Rong;  Xiong,Wen-Yong;  Qiu,Ming -Hua
Adobe PDF(5711Kb)  |  收藏  |  浏览/下载:120/34  |  提交时间:2022/04/02
Ganoderma applanatum  Lanostane triterpenoids  Antiadipogenic effects  LANOSTANE-TYPE TRITERPENOIDS  ACID  
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
作者:  Munikishore,Rachakunta;  Wang,Liang-Liang;  Zhang,Shuqun;  Zhao,Qin-Shi;  Zuo,Zhili
Adobe PDF(523Kb)  |  收藏  |  浏览/下载:94/26  |  提交时间:2022/04/02
Cathepsin L  small-molecule inhibitor  gram-scale synthesis  KGP94  cancer  FUNCTIONALIZED BENZOPHENONE  BIOLOGICAL EVALUATION  TUMOR PROGRESSION  CELL INVASION  EXPRESSION  ANALOGS  SUPPRESSION  DERIVATIVES  ACID  
Polymethylated acylphloroglucinols from Rhodomyrtus tomentosa exert acetylcholinesterase inhibitory effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 107, 页码: 104519
作者:  Qin,Xu-Jie;  Liu,Hui;  Li,Pan-Pan;  Ni,Wei;  He,Li;  Khan,Afsar;  Hao,Xiao-Jiang;  Liu,Hai-Yang
浏览  |  Adobe PDF(2105Kb)  |  收藏  |  浏览/下载:145/68  |  提交时间:2022/04/02
Rhodomyrtus tomentosa  Polymethylated acyphloroglucinols  AChE inhibitory effect  Molecular docking  PHLOROGLUCINOL MEROTERPENOIDS  LEAVES  DERIVATIVES  TWIGS  BETA