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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
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Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Polyphyllin I combined with doxorubicin shows chemosensitization effect in vivo and reduces immunotoxicity of doxorubicin 期刊论文
MOLECULAR & CELLULAR TOXICOLOGY, 2022, 卷号: 18, 期号: 3, 页码: 359-369
作者:  Zhu, Xiang;  Na, Xin;  Zeng, Yueqin;  Xu, Yangantai;  Chai, Dongya;  Yang, Huanzhi;  Miao, Jingqian;  Zhang, Yuan;  Yang, Fenghua;  Wang, Yuehu;  Zhou, Yiping
浏览  |  Adobe PDF(1889Kb)  |  收藏  |  浏览/下载:72/12  |  提交时间:2024/04/30
Polyphyllin I  Chemosensitization  Doxorubicin  Immunotoxicity  Hemolysis  BREAST-CANCER CELLS  SAPONIN  INHIBITION  RESISTANCE  CISPLATIN  
Paris Saponin VII Induces Apoptosis and Cell Cycle Arrest in Erythroleukemia Cells by a Mitochondrial Membrane Signaling Pathway 期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 4, 页码: 498-507
作者:  Lin,Xin;  Gajendran,Babu;  Varier,Krishnapriya M.;  Liu,Wuling;  Song,Jingrui;  Rao,Qing;  Wang,Chunlin;  Qiu,Jianfei;  Ni,Wei;  Qin,XuJie;  Wen,Min;  Liu,Haiyang;  Li,Yanmei
收藏  |  浏览/下载:142/0  |  提交时间:2022/04/02
Leukemia  Paris Saponin VII  HEL  cell cycle  apoptosis  membrane signaling pathway  
Previously undescribed pyridyl-steroidal glycoalkaloids and 23S,26R-hydroxylated spirostanoid saponin from the fruits of Solanum violaceum ortega and their bioactivities 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 184, 页码: 112656
作者:  Kaunda,Joseph Sakah;  Qin,Xu-Jie;  Zhu,Hong-Tao;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
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Solanum violaceum  Solanaceae  Glycoalkaloids  Solanindiosides A-C  235,26R-hydroxylated spirostanoid saponin  Lignans  Cytotoxicity  Apoptosis  Antibacterial  Staphylococcus aureus  
Oleanane-type triterpene saponins from Hydrocotyle nepalensis 期刊论文
FITOTERAPIA, 2016, 卷号: 110, 页码: 66-71
作者:  Ma, Rui-Jing;  Liu, Zhen-Hua;  Zi, Cheng-Ting;  Gao, Wei;  Dong, Fa-Wu;  Yang, Liu;  Li, Jin-Yu;  Zhou, Jun;  Hu, Jiang-Miao
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Hydrocotyle Nepalensis  Oleanane-type Triterpene Saponin  Cytotoxic Activity  
Antimicrobial steroidal saponin and oleanane-type triterpenoid saponins from Paullinia pinnata 期刊论文
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2014, 卷号: 14, 页码: 369
作者:  Lunga, Paul K.;  Qin, Xu-Jie;  Yang, Xing W.;  Kuiate, Jules-Roger;  Du, Zhi Z.;  Gatsing, Donatien;  Du,ZZ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  duzhizhi@mail.kib.ac.cn;  gatsingd@yahoo.com
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Paullinia Pinnata  Sapindaceae  Steroidal Saponin  Oleanane Triterpenoid Saponins  Antimicrobial Activities  
Chemical and morphological variations of Panax notoginseng and their relationship 期刊论文
PHYTOCHEMISTRY, 2013, 卷号: 93, 页码: 88-95
作者:  Wang, Dong;  Koh, Hwee-Ling;  Hong, Yan;  Zhu, Hong-Tao;  Xu, Min;  Zhang, Ying-Jun;  Yang, Chong-Ren
浏览  |  Adobe PDF(1195Kb)  |  收藏  |  浏览/下载:346/100  |  提交时间:2013/10/16
Panax Notoginseng  Araliaceae  Saponin  Phenotype  Variation  Relationship  
A cytotoxic cardenolide and a saponin from the rhizomes of Tupistra chinensis 期刊论文
FITOTERAPIA, 2012, 卷号: 83, 期号: 8, 页码: 1489-1493
作者:  Pan, Zheng-Hong;  Li, Yan;  Liu, Jin-Lei;  Ning, De-Sheng;  Li, Dian-Peng;  Wu, Xing-De;  Wen, Yong-Xin
浏览  |  Adobe PDF(234Kb)  |  收藏  |  浏览/下载:242/88  |  提交时间:2015/06/17
Tupistra Chinensis  Cardenolide  Steroidal Saponin  Tupichinolide  Tupichinin a  Cytotoxicity  
The processing of Panax notoginseng and the transformation of its saponin components 期刊论文
FOOD CHEMISTRY, 2012, 卷号: 132, 期号: 4, 页码: 1808-1813
作者:  Wang, Dong;  Liao, Peng-Ying;  Zhu, Hong-Tao;  Chen, Ke-Ke;  Xu, Min;  Zhang, Ying-Jun;  Yang, Chong-Ren
Adobe PDF(736Kb)  |  收藏  |  浏览/下载:1183/323  |  提交时间:2012/06/07
Panax Notoginseng  Process  Saponin  Transformation  
New pregnane saponins from Ecdysanthera rosea and their cytotoxicity 期刊论文
FITOTERAPIA, 2011, 卷号: 82, 期号: 4, 页码: 632-636
作者:  Zhu, Xiangdong;  Wu, Guisheng;  Xiang, Jianying;  Luo, Huairong;  Luo, Shide;  Zhu, Hongmei;  Wang, Yifen
Adobe PDF(304Kb)  |  收藏  |  浏览/下载:430/153  |  提交时间:2012/03/16
Ecdysanthera Rosea  Pregnane Saponin  Ecdysantheroside b  Cytotoxicity