| New pregnane saponins from Ecdysanthera rosea and their cytotoxicity | |
Zhu, Xiangdong1,2; Wu, Guisheng1 ; Xiang, Jianying3; Luo, Huairong1; Luo, Shide1; Zhu, Hongmei4; Wang, Yifen1
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| 通讯作者 | xdzhu815@yahoo.com.cn ; wangyifen@mail.kib.ac.cn |
| 2011-06-01 | |
| 发表期刊 | FITOTERAPIA
 |
| ISSN | 0367-326X |
| 卷号 | 82期号:4页码:632-636 |
| 摘要 | Two new pregnane saponins elucidated as ecdysantheroside A (1) and ecdysantheroside B (2) and six known compounds (3-8) based on spectral data (MS, IR, 1D and 2D NMR) were isolated from the stem bark of Ecdysanthera rosea. The cytotoxicity against six cell lines of these compounds was tested by MTT assay. The results revealed that compounds 5 and 7 showed cytotoxicity against all the cell lines. Compound 2 showed cytotoxicity against cells A549, MDA435, HepG2, and HUVEC, while compound 4 showed cytotoxicity against cells A549, CEM, and HUVEC. Compound 6 had cytotoxicity against the others except cell HepG2. (C) 2011 Elsevier B.V. All rights reserved. |
| 关键词 | Ecdysanthera Rosea Pregnane Saponin Ecdysantheroside b Cytotoxicity |
| 学科领域 | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| DOI | 10.1016/j.fitote.2011.01.022 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000291140800018 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/3940 |
| 专题 | 中国科学院东亚植物多样性与生物地理学重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.Jiangxi Agr Univ, Coll Biosci & Bioengn, Nanchang 330045, Peoples R China 3.Chinese Acad Sci, Key Lab Biodivers & Biogeog, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China 4.Xiamen Univ, Coll Oceanog & Environm Sci, Xiamen 361000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Xiangdong,Wu, Guisheng,Xiang, Jianying,et al. New pregnane saponins from Ecdysanthera rosea and their cytotoxicity[J]. FITOTERAPIA,2011,82(4):632-636. |
| APA | Zhu, Xiangdong.,Wu, Guisheng.,Xiang, Jianying.,Luo, Huairong.,Luo, Shide.,...&Wang, Yifen.(2011).New pregnane saponins from Ecdysanthera rosea and their cytotoxicity.FITOTERAPIA,82(4),632-636. |
| MLA | Zhu, Xiangdong,et al."New pregnane saponins from Ecdysanthera rosea and their cytotoxicity".FITOTERAPIA 82.4(2011):632-636. |
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