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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
浏览  |  Adobe PDF(6987Kb)  |  收藏  |  浏览/下载：198/35  |  提交时间：2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
重楼属中富含偏诺甾体皂苷的植物资源挖掘及其研究 学位论文
: 中国科学院大学, 2022
作者:  余玲玲
Adobe PDF(11095Kb)  |  收藏  |  浏览/下载：181/0  |  提交时间：2024/05/14
重楼属 (Paris L.)，黑药花科，偏诺皂苷，球药隔重楼，LC-MS/MS，诱导血小板聚集活性  Paris L., Melanthiaceae, Pennogenin saponins, Paris fargesii, LC-MS/MS, Inducing platelet aggregation activity  
Polyphyllin I combined with doxorubicin shows chemosensitization effect in vivo and reduces immunotoxicity of doxorubicin 期刊论文
MOLECULAR & CELLULAR TOXICOLOGY, 2022, 卷号: 18, 期号: 3, 页码: 359-369
作者:  Zhu, Xiang;  Na, Xin;  Zeng, Yueqin;  Xu, Yangantai;  Chai, Dongya;  Yang, Huanzhi;  Miao, Jingqian;  Zhang, Yuan;  Yang, Fenghua;  Wang, Yuehu;  Zhou, Yiping
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Polyphyllin I  Chemosensitization  Doxorubicin  Immunotoxicity  Hemolysis  BREAST-CANCER CELLS  SAPONIN  INHIBITION  RESISTANCE  CISPLATIN  
丫蕊花中水溶性皂苷的制备及其活性评价 学位论文
, 2021
作者:  张仕娟
Adobe PDF(5526Kb)  |  收藏  |  浏览/下载：55/0  |  提交时间：2024/03/20
Ecdysteroids and spirosterane steroids from the traditional Chinese medicine Paris polyphylla var. yunnanensis 期刊论文
PHYTOCHEMISTRY LETTERS, 2021, 卷号: 45, 页码: 117-120
作者:  Guo,Kai;  Ren,Xue;  Mu,Rong-Fang;  Zhou,Ting-Ting;  Li,Dan;  Hu,Hong;  Liu,Yan;  Li,Sheng-Hong
浏览  |  Adobe PDF(1083Kb)  |  收藏  |  浏览/下载：312/107  |  提交时间：2022/04/02
Paris polyphylla var  yunnanensis  Liliaceae  Ecdysteroids  Spirostane steroids  SAPONINS  GLYCOSIDES  CONSTITUENTS  RHIZOMES  LEAVES  STEMS  
Furostanol Saponins from Asparagus cochinchinensis and Their Cytotoxicity. 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 6, 页码: 651-658
作者:  Zhang,Ruo-Song;  Liu,Yang-Yang;  Zhu,Pei-Feng;  Jin,Qiong;  Dai,Zhi;  Luo,Xiao-Dong
浏览  |  Adobe PDF(1291Kb)  |  收藏  |  浏览/下载：259/76  |  提交时间：2022/04/02
Cloning and Functional Characterization of a Squalene Synthase from Paris polyphylla var. yunnanensis 期刊论文
CHEMISTRY & BIODIVERSITY, 2021, 卷号: 18, 期号: 7
作者:  Gao,Jian-Xiong;  Chen,Yue-Gui;  Li,De-Sen;  Lin,Liang;  Liu,Yan;  Li,Sheng-Hong
浏览  |  Adobe PDF(5087Kb)  |  收藏  |  浏览/下载：298/62  |  提交时间：2022/04/02
Paris polyphylla var  Yunnanensis  squalene synthase  steroidal saponins  squalene  in vitro enzymatic assay  MOLECULAR-CLONING  SAPONINS  EXPRESSION  GENE  GLYCOSIDES  PLANTS  SQS  
Molecular networking uncovers steroidal saponins of Paris tengchongensis (vol 145, 104629, 2020) 期刊论文
FITOTERAPIA, 2021, 卷号: 150, 页码: 104830
作者:  Wang,Jie;  Li,Dan;  Ni,Wei;  Qin,Xu-Jie;  Liu,Hui;  Yu,Ling-Ling;  Qiao,Xue;  Ji,Yun-Heng;  He,Li;  Nian,Si-Hui;  Liu,Hai-Yang
浏览  |  Adobe PDF(2144Kb)  |  收藏  |  浏览/下载：292/93  |  提交时间：2022/04/02
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
作者:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
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Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Previously undescribed pyridyl-steroidal glycoalkaloids and 23S,26R-hydroxylated spirostanoid saponin from the fruits of Solanum violaceum ortega and their bioactivities 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 184, 页码: 112656
作者:  Kaunda,Joseph Sakah;  Qin,Xu-Jie;  Zhu,Hong-Tao;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
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Solanum violaceum  Solanaceae  Glycoalkaloids  Solanindiosides A-C  235,26R-hydroxylated spirostanoid saponin  Lignans  Cytotoxicity  Apoptosis  Antibacterial  Staphylococcus aureus