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Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin-1a receptor in primary sensory neurons1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-34
作者:  Fang Qiu;  Chun-Yu Qiu;  Huilan Cai;  Ting-Ting Liu;  Zu-Wei Qu;  Zhifan Yang;  Jia-Da Li;  Qun-Yong Zhou;  Wang-Ping Hu
Adobe PDF(850Kb)  |  收藏  |  浏览/下载:334/1  |  提交时间:2017/07/24
Oxytocin  Acid-sensing Ion Channel  Proton-gated Current  Vasopressin-1a Receptor  Dorsal Root Ganglion Neuron  Electrophysiology  Pain  
The TRPC channel blocker SKF 96365 Inhibits Glioblastoma Cell Growth by Enhancing Reverse Mode of the Na+/Ca2+ Exchanger and Increasing Intracellular Ca2+ 期刊论文
出版物, 3111, 期号: 0, 页码: 1-45
作者:  M Song;  D Chen;  S P Yu
Adobe PDF(1390Kb)  |  收藏  |  浏览/下载:216/1  |  提交时间:2017/07/24
Skf 96365  Trpc Channel  Glioblastoma  Calcium  na+/ca2+ Exchanger  Cell Cycle  Cell Death  
The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1 期刊论文
出版物, 2111, 页码: 1-44
作者:  1M S Grace;  T Lieu;  B Darby;  F C Abogadie;  N Veldhuis N W Bunnett;  P McIntyre
Adobe PDF(1611Kb)  |  收藏  |  浏览/下载:168/1  |  提交时间:2017/07/24
Transient Receptor Potential Ion Channel  Trpv4  Protease Activated Receptor  Par2  Pain  Tyrosine Kinase  Bafetinib  
Discovery of potential novel TRPC5 inhibitors by virtual screening and bioassay 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 94, 页码: 117477
作者:  Shen,Meiling;  Li,Lingfeng;  Li,Yue;  Gu,Xi;  Bai,Longhui;  Xia,Chengfeng;  Xiong,Wenyong;  Zuo,Zhili
浏览  |  Adobe PDF(6089Kb)  |  收藏  |  浏览/下载:48/15  |  提交时间:2024/07/22
TRPC5  Inhibitors  Virtual screening  Ca 2+channel  CHANNELS  IDENTIFICATION  PERMEABILITY  CALCIUM  
Abietane derived diterpenoids as Cav3.1 antagonists from Salvia digitaloides 期刊论文
CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 4, 页码: 107737
作者:  Zhao,Jianjun;  Du,Shuzong;  Hu,Kun;  Hu,Yali;  Xia,Fan;  Ye,Yansong;  Yang,Jian;  Nian,Yin;  Xu,Gang
浏览  |  Adobe PDF(1277Kb)  |  收藏  |  浏览/下载:63/9  |  提交时间:2024/07/22
10-Methylated 6  7  6 carbon ring system  Icetexane  Diterpenoid  Salvia digitaloides  Ca v 3  1 low voltage -gated Ca 2+channel  (LVGCC)  ROOTS  TANSHINLACTONE  CONSTITUENTS  ELUCIDATION  INHIBITORS  CHANNELS  SKELETON  SYSTEM  
Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin;  Zuo,Zhili
浏览  |  Adobe PDF(5035Kb)  |  收藏  |  浏览/下载:49/9  |  提交时间:2024/07/22
Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION  
先导化合物设计与开发 学位论文
: 中国科学院大学, 2022
作者:  Munikishore Rachakunta
Microsoft Word(14465Kb)  |  收藏  |  浏览/下载:43/0  |  提交时间:2024/05/14
Buxus alkaloids  Buxus alkaloids  Cyclovirobuxine-D  Cyclovirobuxine-D  Synthesis, Calcium channel inhibitors  Synthesis, Calcium channel inhibitors  SAR studies  SAR studies  Anti-cardiovascular agents.  Anti-cardiovascular agents.  
T-型钙通道天然活性分子挖掘及其在治疗疼痛中的应用 学位论文
: 中国科学院大学, 2022
作者:  李松谕
Adobe PDF(5173Kb)  |  收藏  |  浏览/下载:42/0  |  提交时间:2024/05/14
T-型钙通道,PPAP类化合物,黄酮类化合物  Key words: T-type calcium channel, PPAP, isoprenylated flavonoids  
Discovery of novel coffee diterpenoids with inhibitions on Ca(v)3.1 low voltage-gated Ca2+ channel 期刊论文
FOOD CHEMISTRY, 2022, 卷号: 376, 页码: 131923
作者:  Hu,Guilin;  Dong,Ding;  Du,Shuzong;  Peng,Xingrong;  Wu,Mingkun;  Shi,Qiangqiang;  Hu,Kun;  Hong,Defu;  Wang,Xiaoyuan;  Zhou,Lin;  Nian,Yin;  Qiu,Minghua
Adobe PDF(4722Kb)  |  收藏  |  浏览/下载:252/78  |  提交时间:2022/04/02
Coffea arabica L  Roasted coffee  Coffee diterpenoid  Cafestol  Kahweol  T-type Ca2+ channels  Ca(v)3.1 low voltage-gated Ca2+ channel  Ca(v)3.1 inhibitors  CALCIUM-CHANNELS  CAFESTOL  KAHWEOL  PHYSIOLOGY  ESTERS  NOMENCLATURE  PHARMACOLOGY  APOPTOSIS  FURANS  
Genome-Wide Identification and Functional Analysis of the Calcineurin B-like Protein and Calcineurin B-like Protein-Interacting Protein Kinase Gene Families in Chinese Cabbage (Brassica rapa ssp. pekinensis) 期刊论文
GENES, 2022, 卷号: 13, 期号: 5, 页码: 795
作者:  Wang, Qianwen;  Zhao, Kai;  Gong, Yuqiang;  Yang, Yunqiang;  Yue, Yanling
Adobe PDF(4079Kb)  |  收藏  |  浏览/下载:71/17  |  提交时间:2024/04/30
abiotic stresses  BraCBL-BraCIPK  Chinese cabbage  expression profiles  functional differentiation  preferential interactions  CALCIUM SENSOR  PHYLOGENETIC ANALYSIS  ION HOMEOSTASIS  PLANT-GROWTH  ORYZA-SATIVA  ARABIDOPSIS  EVOLUTION  RESPONSES  CHANNEL  DOMAIN