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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
浏览  |  Adobe PDF(6987Kb)  |  收藏  |  浏览/下载：73/11  |  提交时间：2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Cyclovirobuxine D, a cardiovascular drug from traditional Chinese medicine, alleviates inflammatory and neuropathic pain mainly via inhibition of voltage-gated Ca(v)3.2 channels 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 1081697
作者:  Su, Deyuan;  Gong, Ye;  Li, Songyu;  Yang, Jian;  Nian, Yin
浏览  |  Adobe PDF(3909Kb)  |  收藏  |  浏览/下载：26/5  |  提交时间：2024/08/21
Cyclovirobuxine D  Ca(v)3  2  Ca(v)2  Buxus microphylla  analgesic effects  ROOT GANGLION NEURONS  CALCIUM-CHANNELS  CELL-PROLIFERATION  PACLITAXEL  RAT  RECEPTOR  GENE  EXPRESSION  APOPTOSIS  CURRENTS  
Monoterpene Indole Alkaloids with Ca(v)3.1 T-Type Calcium Channel Inhibitory Activity from Catharanthus roseus 期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 21, 页码: 6516
作者:  Deng,Zhen-Tao;  Li,Wen-Yan;  Wang,Lei;  Zhou,Zhi-Ping;  Wu,Xing-De;  Ding,Zhong-Tao;  Zhao,Qin-Shi
浏览  |  Adobe PDF(2354Kb)  |  收藏  |  浏览/下载：195/70  |  提交时间：2022/04/02
Catharanthus roseus  monoterpene indole alkaloid  catharanosine A  Ca(v)3  1 low voltage-gated calcium channel (LVGCC)  VINCA ALKALOIDS  CELL-PROLIFERATION  N-OXIDE  SARPAGINE  BIOSYNTHESIS  VINORELBINE  VINBLASTINE  MECHANISM  ROOTS  BASES  
The F-box protein MIO1/SLB1 regulates organ size and leaf movement in Medicago truncatula 期刊论文
JOURNAL OF EXPERIMENTAL BOTANY, 2021, 卷号: 72, 期号: 8, 页码: 2995-3011
作者:  Zhou,Shaoli;  Yang,Tianquan;  Mao,Yawen;  Liu,Ye;  Guo,Shiqi;  Wang,Ruoruo;  Fangyue,Genwang;  He,Liangliang;  Zhao,Baolin;  Bai,Quanzi;  Li,Youhan;  Zhang,Xiaojia;  Wang,Dongfa;  Wang,Chaoqun;  Wu,Qing;  Yang,Yuanfan;  Liu,Yu;  Tadege,Million;  Chen,Jianghua
收藏  |  浏览/下载：131/0  |  提交时间：2022/04/02
BIG SEEDS1 (BS1)  F-box protein  MINI ORGAN1 (MIO1)/SMALL LEAF AND BUSHY1 (SLB1)  SCF E3 ligase  proteasome-mediated degradation  organ size  pulvinus  CELL-PROLIFERATION  ARABIDOPSIS-THALIANA  TRANSCRIPTION FACTOR  SEED SIZE  GROWTH  GENE  IDENTIFICATION  KINASES  CYCLE  E2FB  
Genome-Wide Identification and Characterization of BrrTCP Transcription Factorsin Brassica rapa ssp rapa 期刊论文
FRONTIERS IN PLANT SCIENCE, 2017, 卷号: 8, 期号: 1, 页码: 1588
作者:  Du, Jiancan;  Hu, Simin;  Yu, Qin;  Wang, Chongde;  Yang, Yunqiang;  Sun, Hang;  Yang, Yongping;  Sun, Xudong
浏览  |  Adobe PDF(4668Kb)  |  收藏  |  浏览/下载：201/41  |  提交时间：2017/10/23
Tcp  Transcription Factors  Expression Analysis  Turnip  Cell Proliferation  
Isocostunolide inhibited glioma stem cell by suppression proliferation and inducing caspase dependent apoptosis 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 页码: 2863-2867
作者:  Dai, Zhi;  Li, Shi-Rong;  Zhu, Pei-Feng;  Liu, Lu;  Wang, Bei;  Liu, Ya-Ping;  Luo, Xiao-Dong;  Zhao, Xu-Dong
浏览  |  Adobe PDF(2209Kb)  |  收藏  |  浏览/下载：320/70  |  提交时间：2017/07/18
Isocostunolide  Glioma Stem Cells  Cell Proliferation  Apoptosis  Colony Formation  
Melodinine V, an antitumor bisindole alkaloid with selective cytotoxicity from Melodinus henryi 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 20, 页码: 4895-4898
作者:  Liu, Ya-Ping;  Yue, Grace Gar-Lee;  Lee, Julia Kin-Ming;  Feng, Tao;  Zhao, Yun-Li;  Li, Yan;  Lau, Clara Bik-San;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1084Kb)  |  收藏  |  浏览/下载：310/95  |  提交时间：2017/01/05
Melodinine v  Bisindole  Inhibited Cell Proliferation  Cell Cycle Arrest  Cellular Apoptosis  Ht-29 Cells  
AS160 controls eukaryotic cell cycle and proliferation by regulating the CDK inhibitor p21 期刊论文
CELL CYCLE, 2016, 卷号: 15, 期号: 13, 页码: 1733-1741
作者:  Gongpan, Pianchou;  Lu, Yanting;  Wang, Fang;  Xu, Yuhui;  Xiong, Wenyong
浏览  |  Adobe PDF(1876Kb)  |  收藏  |  浏览/下载：322/66  |  提交时间：2016/10/19
As160/tbc1d4  Cell Cycle  Cell Proliferation  G1/s  P21  
Ethoxysanguinarine Induces Inhibitory Effects and Downregulates CIP2A in Lung Cancer Cells 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 5, 期号: 2, 页码: 113-118
作者:  Liu, Zi;  Ma, Liang;  Wen, Zhe-Sheng;  Cheng, Yong-Xian;  Zhou, Guang-Biao
浏览  |  Adobe PDF(415Kb)  |  收藏  |  浏览/下载：459/83  |  提交时间：2014/04/09
Ethoxysanguinarine  Cip2a  Lung Cancer  Cell Proliferation  Apoptosis  
Hitting the Golden TORget: Curcumin's Effects on mTOR Signaling 期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2013, 卷号: 13, 期号: 7, 页码: 988-994
作者:  Beevers, Christopher S.;  Zhou, Hongyu;  Huang, Shile
浏览  |  Adobe PDF(230Kb)  |  收藏  |  浏览/下载：244/41  |  提交时间：2013/10/16
Curcumin  Mtor  Akt  Cancer  Cell Proliferation  Cell Death