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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
浏览  |  Adobe PDF(6987Kb)  |  收藏  |  浏览/下载：8/2  |  提交时间：2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
作者:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
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Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway 期刊论文
PHYTOMEDICINE, 2023, 卷号: 116, 页码: 154898
作者:  Geng,Chang-An;  Chen,Feng-Yang;  Zheng,Jing-Bin;  Liao,Ping;  Li,Tian-Ze;  Zhang,Xue-Mei;  Chen,Xin;  Chen,Ji-Jun
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Rubiginosin B (RGB)  CD4(+)Foxp3(+) regulatory T cells (Tregs)  Calcineurin  Nuclear factor of activated T cells (NFAT)  Tumor microenvironment  Rhododendron brachypodum  REGULATORY T-CELLS  RHODODENDRON  IMMUNOSUPPRESSION  DERIVATIVES  INDUCTION  EXPANSION  RAPAMYCIN  
Pharmacological investigation of indole alkaloids from Alstonia scholaris against chronic glomerulonephritis 期刊论文
PHYTOMEDICINE, 2023, 卷号: 118, 页码: 154958
作者:  Guo,Rui;  Shang,Jian-Hua;  Ye,Rui-Han;  Zhao,Yun-Li;  Luo,Xiao-Dong
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Alstonia scholaris  Indole alkaloids  Chronic glomerulonephritis  Network pharmacology  PI3K-AkT pathway  LEAVES  IDENTIFICATION  CONSTITUENTS  EXTRACT  MODELS  POTENT  
Indole-3-acetonitrile Is a Critical Molecule with Weed Allopathic Suppression Function in Broccoli (Brassica oleracea var. italica) 期刊论文
CHEMISTRY & BIODIVERSITY, 2023, 卷号: 20, 期号: 7
作者:  Liu,Wanyou;  Dong,Bao Zhu;  Hu,Jinghan;  Xu,Zhenpeng;  Zheng,Chengzhong;  Nian,Yin;  Zhou,Hongyou
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allelopathy  entropy method-based topsis  herbicidal activity  indole-3-acetonitrile  purification  INDOLE GLUCOSINOLATE  SEED-GERMINATION  MANAGEMENT  EXTRACTS  GROWTH  AUXIN  ALLELOPATHY  HYDROLYSIS  LETTUCE  TISSUES  
Sesquiterpenoids from the Resina Commiphora Promoting the Apoptotic Activity of PC-3 Prostate Cancer Cells 期刊论文
CHEMISTRY & BIODIVERSITY, 2023
作者:  Dong,Lu;  Li,Yanpeng;  Qin,Fuying;  Cheng,Yongxian
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Resina Commiphora  germacrane sesquiterpenes  cell viability  apoptosis  PC-3 cells  ANTIOXIDANT  MYRRHA  BERRYI  MUKUL  
Abietane derived diterpenoids as Cav3.1 antagonists from Salvia digitaloides 期刊论文
CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 4, 页码: 107737
作者:  Zhao,Jianjun;  Du,Shuzong;  Hu,Kun;  Hu,Yali;  Xia,Fan;  Ye,Yansong;  Yang,Jian;  Nian,Yin;  Xu,Gang
浏览  |  Adobe PDF(1277Kb)  |  收藏  |  浏览/下载：8/3  |  提交时间：2024/07/22
10-Methylated 6  7  6 carbon ring system  Icetexane  Diterpenoid  Salvia digitaloides  Ca v 3  1 low voltage -gated Ca 2+channel  (LVGCC)  ROOTS  TANSHINLACTONE  CONSTITUENTS  ELUCIDATION  INHIBITORS  CHANNELS  SKELETON  SYSTEM  
Phylogeny and Taxonomic Revision of the Family Discinaceae (Pezizales, Ascomycota) 期刊论文
MICROBIOLOGY SPECTRUM, 2023
作者:  Wang,Xin-Cun;  Yang,Zhu-Liang;  Chen,Shuang-Lin;  Bau,Tolgor;  Li,Tai-Hui;  Li,Lin;  Fan,Li;  Zhuang,Wen-Ying
浏览  |  Adobe PDF(1971Kb)  |  收藏  |  浏览/下载：40/10  |  提交时间：2024/05/09
Ascomycota  phylogeny  taxonomy  3 new genera  2 new species  TRUE MORELS MORCHELLA  GYROMITRA  FUNGI  HELVELLACEAE  DIVERSITY  EVOLUTION  REVEALS  CLASSIFICATION  SYSTEMATICS  HYDNOTRYA  
Multiomics strategies for decoding seed dormancy breakdown in Paris polyphylla 期刊论文
BMC PLANT BIOLOGY, 2023, 卷号: 23, 期号: 1, 页码: 247
作者:  Zheng,Guowei;  Li,Wenchun;  Zhang,Shunzhen;  Mi,Qi;  Luo,Wenxiu;  Zhao,Yanli;  Qin,Xiangshi;  Li,Weijiao;  Pu,Shibiao;  Xu,Furong
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Paris polyphylla  Seed dormancy  Metabolomics  Transcriptomics  Gibberellin A(3)  Gibberellin A(4)  ABSCISIC-ACID  PROTEOMIC ANALYSIS  GIBBERELLIN  GERMINATION  STRATIFICATION  BIOSYNTHESIS  ARABIDOPSIS  REVEALS  
RUNX1-Regulated Signaling Pathways in Ovarian Cancer 期刊论文
BIOMEDICINES, 2023, 卷号: 11, 期号: 9, 页码: 2357
作者:  Chen,Yuanzhi;  He,Yingying;  Liu,Shubai
浏览  |  Adobe PDF(1447Kb)  |  收藏  |  浏览/下载：33/12  |  提交时间：2024/05/09
Runt-related transcription factor 1 (RUNX1)  ovarian cancer  apoptosis  signaling pathways  clinical therapeutic target  GROWTH-FACTOR  TRANSCRIPTION FACTORS  STEM-CELLS  RUNX1  STAT3  FAMILY  ACTIVATION  APOPTOSIS  LEUKEMIA  SURVIVAL