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Munronin V with 7/7/6 tricarbocyclic framework from Munronia henryi harms inhibits tau pathology by activating autophagy 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 3, 页码: 514-519
作者:  Yan,Ying;  Ran,Xiaoqian;  Wang,Dan;  Zhang,Xiong;  Peng,Mingyou;  Yan,Xiaoyan;  Tang,Lei;  Liang,Hong;  Qin,Xujie;  Di,Ying-Tong;  Luo,Rongcan;  Hao,Xiao-Jiang;  Yao,Yong-Gang
浏览  |  Adobe PDF(1471Kb)  |  收藏  |  浏览/下载：121/27  |  提交时间：2024/07/25
UBIQUITIN-PROTEASOME SYSTEM  ALZHEIMERS-DISEASE  CONSTITUENTS  LIMONOIDS  TFEB  NEURODEGENERATION  
New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit beta-Amyloid42 Production and Phospho-Tau (Thr217) 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1487
作者:  Li,Sheng;  Han,Ling-Ling;  Huang,Ke-Pu;  Ma,Ye-Han;  Guo,Ling-Li;  Guo,Yarong;  Ran,Xiaoqian;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rongcan;  Zhang,Yu
浏览  |  Adobe PDF(5266Kb)  |  收藏  |  浏览/下载：89/20  |  提交时间：2024/05/09
Tabernaemontana crassa  monoterpenoid indole alkaloids  A beta 42  phospho-tau (Thr217)  Alzheimer's disease  ALZHEIMERS-DISEASE  BISINDOLE ALKALOIDS  CDK5  GEMFIBROZIL  PREVENTION  ALGORITHM  AUTOPHAGY  MODELS  PLANTS  MOUSE  
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway 期刊论文
HELIYON, 2023, 卷号: 9, 期号: 2, 页码: e13691
作者:  Ran,Xiaoqian;  Lu,Qing-Yun;  Li,Ying-Yao;  Pu,Xue-Xue;  Guo,Yarong;  Yuan,Ming-Rui;  Guan,Shi-Peng;  Sun,Mao;  Jiao,Lijin;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang;  Luo,Rongcan
浏览  |  Adobe PDF(10283Kb)  |  收藏  |  浏览/下载：107/35  |  提交时间：2024/07/30
Euphorbia peplus L  Euphorbiaceae  Ent-abietane diterpenoid  Euphejolkinolide A  Autophagy-lysosomal pathway  ALZHEIMERS-DISEASE  TAU PATHOLOGY  NEURODEGENERATION  DITERPENOIDS  INHIBITION  MECHANISMS  APOPTOSIS  CELASTROL  PROTEIN  SYSTEM  
Prebiotic-Based Nanoamorphous Atorvastatin Attenuates Nonalcoholic Fatty Liver Disease by Retrieving Gut and Liver Health 期刊论文
SMALL STRUCTURES, 2023, 页码: 2200312
作者:  Cui,Jin-Jin;  Li,Rui;  Ma,Xiao-Lei;  Yu,Hao-Yang;  Luo,Zhi-Gang;  Du,Peng;  Ren,Ling;  Ding,Xiao;  Guo,Xiu-Ping;  Zheng,Wen-Sheng;  Jiang,Jian-Dong;  Che,Yongsheng;  Wang,Lu-Lu
浏览  |  Adobe PDF(26415Kb)  |  收藏  |  浏览/下载：140/25  |  提交时间：2024/07/30
atorvastatin  gut flora  nanoamorphous  nonalcoholic fatty liver disease  prebiotics  SOLID DISPERSIONS  STATIN USE  EFFICACY  STEATOHEPATITIS  FORMULATION  SAFETY  ABSORPTION  ACTIVATION  MICROBIOTA  CIRRHOSIS  
Perforatactones D and E, two new C-20 quassinoids with potential activity to induce lysosomal biogenesis from the twigs of Harrisonia perforata (Blanco) Merr. 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 44, 页码: 9637-9640
作者:  Liu,Shuai;  Zhang,Cui-Shan;  Ran,Xiao-Qian;  Tang,Xiao-Han;  Guo,Ya-Rong;  Yan,Ying;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rong-Can;  Di,Ying-Tong
浏览  |  Adobe PDF(997Kb)  |  收藏  |  浏览/下载：223/61  |  提交时间：2022/04/02
PROMISING BIOLOGICAL-ACTIVITY  LIMONOIDS  CHROMONES  FRUITS  DRUG  
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(2579Kb)  |  收藏  |  浏览/下载：279/73  |  提交时间：2023/09/08
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 2, 页码: 262-267
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
收藏  |  浏览/下载：131/0  |  提交时间：2022/04/02
AMYLOID PRECURSOR PROTEIN  INSULIN-DEGRADING ENZYME  BETA-PROTEIN  GEMFIBROZIL  PREVENTION  SECRETASE  ADAM10  MEN  
Catalyzed Synthesis of 3-hydroxy-indol-2-one Derivatives as a Novel Phosphodiesterases 10 Inhibitor 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2020, 卷号: 126, 页码: 33-34
作者:  Wu, Ya;  Li, Hao;  Yan, Jiao;  Cai, Qing;  Huang, Shengxiong;  Tang, Ying;  Ji, Yue;  Hao, Xiaojiang;  Chen, Gang
收藏  |  浏览/下载：341/0  |  提交时间：2020/03/24
Synthesis and PDE-10 Inhibition of 3-substituted Phenylimino-indolin-2-ones 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2020, 卷号: 126, 页码: 34-34
作者:  Wu, Ya;  Lin, Zhiwei;  Bai, Yun;  Zhang, Yu;  Cai, Qing;  Mu, Shuzhen;  Han, Weiwei;  Hao, Xiaojiang;  Chen, Gang
收藏  |  浏览/下载：292/0  |  提交时间：2020/03/24
Solid base catalyzed synthesis of chalcone derivatives and the bioactivity of neuromedin U R1 inhibition 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2019, 卷号: 125, 页码: 5-6
作者:  Wang, Wei;  Xue, Yuying;  Mu, Shuzhen;  Hao, Xiaojiang;  Tang, Ying;  Chen, Gang
收藏  |  浏览/下载：225/0  |  提交时间：2019/10/14