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Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice 期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 1829
作者:  Zhao,Qi;  Dai,Man-Yun;  Huang,Ruo-Yue;  Duan,Jing-Yi;  Zhang,Ting;  Bao,Wei-Min;  Zhang,Jing-Yi;  Gui,Shao-Qiang;  Xia,Shu-Min;  Dai,Cong-Ting;  Tang,Ying-Mei;  Gonzalez,Frank J. J.;  Li,Fei
浏览  |  Adobe PDF(5393Kb)  |  收藏  |  浏览/下载：87/15  |  提交时间：2024/05/09
FATTY LIVER-DISEASE  INDUCED CHOLESTASIS  STELLATE CELLS  PROBIOTICS  PROTECTS  INFLAMMATION  APOPTOSIS  OBESITY  AXIS  
雷公藤制剂对消化系统的毒性机理研究 学位论文
: 中国科学院大学, 2022
作者:  代曼云
Adobe PDF(10574Kb)  |  收藏  |  浏览/下载：18/0  |  提交时间：2024/05/14
代谢组学，雷公藤，药源性肝损伤，消化性溃疡，FXR，ET-1， 肠道血管屏障  Metabolomics, Tripterygium wilfordii, Drug-induced liver injury, peptic ulcer disease, FXR, ET-1, intestinal vascular barrier.  
Polyamine metabolism links gut microbiota and testicular dysfunction 期刊论文
MICROBIOME, 2021, 卷号: 9, 期号: 1, 页码: 224
作者:  Zhao,Qi;  Huang,Jian-Feng;  Cheng,Yan;  Dai,Man-Yun;  Zhu,Wei-Feng;  Yang,Xiu-Wei;  Gonzalez,Frank J.;  Li,Fei
收藏  |  浏览/下载：98/0  |  提交时间：2022/04/02
Testicular dysfunction  Gut microbiota  Polyamine metabolism  Metabolomics  SMALL-MOLECULE INHIBITOR  ORNITHINE-DECARBOXYLASE  TRIPTOLIDE  SPERMINE  ACTIVATION  DISRUPTION  MECHANISMS  EXPRESSION  APOPTOSIS  TRANSPORT  
Discovery and validation of quality markers of Fructus Aurantii against acetylcholinesterase using metabolomics and bioactivity assays 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 卷号: 44, 期号: 11, 页码: 2189-2205
作者:  Wang,Yi-Kun;  Zhou,Zi-Meng;  Dai,Man-Yun;  Ma,Xiao-Fang;  Xiao,Xue-Rong;  Zhang,Shou-Wen;  Liu,Hong-Ning;  Li,Fei
浏览  |  Adobe PDF(2083Kb)  |  收藏  |  浏览/下载：149/44  |  提交时间：2022/04/02
Fructus Aurantii  quality markers  metabolomics  serum pharmacochemistry  ultra high performance liquid chromatography  SERUM PHARMACOCHEMISTRY  RAT PLASMA  IDENTIFICATION  METABOLITES  IMMATURUS  COMPONENTS  EXTRACT  NEOHESPERIDIN  FINGERPRINT  NARINGIN  
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations 期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
作者:  Peng,Wan;  Dai,Man-Yun;  Bao,Li-Juan;  Zhu,Wei-Feng;  Li,Fei
浏览  |  Adobe PDF(2010Kb)  |  收藏  |  浏览/下载：177/19  |  提交时间：2022/04/02
Tripterygium wilfordii  liver injury  farnesoid X receptor  bile acid metabolism  metabolomics  
Discovery of quality markers in Rubus Chingii Hu using UPLC-ESI-QTOF-MS 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 203, 页码: 114200
作者:  Zhou,Zi-Meng;  Yan,Dong-Mei;  Wang,Yi-Kun;  Zhang,Ting;  Xiao,Xue-Rong;  Dai,Man-Yun;  Zhang,Shou-Wen;  Liu,Hong-Ning;  Li,Fei
收藏  |  浏览/下载：117/0  |  提交时间：2022/04/02
Raspberry  Q-markers  Quality evaluation  UPLC-ESI-QTOF-MS  COMPONENTS  ACTIVATION  PATHWAY  FRUITS  
Gut microbiota protects from triptolide-induced hepatotoxicity: Key role of propionate and its downstream signalling events 期刊论文
PHARMACOLOGICAL RESEARCH, 2020
作者:  Huang, Jian-Feng;  Zhao, Qi;  Dai, Man-Yun;  Xiao, Xue-Rong;  Zhang, Ting;  Zhu, Wei-Feng;  Li, Fei
浏览  |  Adobe PDF(3869Kb)  |  收藏  |  浏览/下载：246/48  |  提交时间：2021/01/05
Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(9057Kb)  |  收藏  |  浏览/下载：308/59  |  提交时间：2020/03/26
A phytochemical investigation of Stemona parviflora roots reveals several compounds with nematocidal activity 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 159, 页码: 208-215
作者:  Huang, Sheng-Zhuo;  Kong, Fan-Dong;  Chen, Gao;  Cai, Xiang-Hai;  Zhou, Li-Man;  Ma, Qing-Yun;  Wang, Qi;  Mei, Wen-Li;  Dai, Hao-Fu;  Zhao, You-Xing
浏览  |  Adobe PDF(614Kb)  |  收藏  |  浏览/下载：424/80  |  提交时间：2019/03/25
Stemona parviflora  Stemonaceae  Phenanthrene  Stilbene  Nematocidal activity