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Development of actein derivatives as potent anti-triple negative breast cancer agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 89, 页码: 129307
作者:  Zhang,Honglin;  Chen,Yiyan;  Huang,Songwen;  Xiao,Wen-Wen;  Qiu,Ming-Hua;  Shao,Li-Dong;  Chen,Chuan-Huizi;  Li,Dashan
浏览  |  Adobe PDF(1187Kb)  |  收藏  |  浏览/下载：37/9  |  提交时间：2024/07/22
Actein  Modification  Triple negative breast cancer  Structure-activity relationships  Mechanism  GROWTH-INHIBITORY ACTIVITY  BLACK COHOSH  EXTRACTS  
Noncoding RNAs and RNA-binding proteins in diabetic wound healing 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 50, 页码: 128311
作者:  Li,Xue;  Li,Ning;  Li,Bingxin;  Feng,Yuan;  Zhou,Di;  Chen,Gang
收藏  |  浏览/下载：101/0  |  提交时间：2022/04/02
ncRNAs  lncRNAs  circRNAs  RNA-binding protein  Modulating drugs  Diabetic  Wound healing  ENDOTHELIAL-CELLS  OXIDATIVE STRESS  PROLIFERATION  APOPTOSIS  INFLAMMATION  DYSFUNCTION  EXPRESSION  MIGRATION  CANCER  INJURY  
Synthesis and anti-fibrotic effects of santamarin derivatives as cytotoxic agents against hepatic stellate cell line LX2 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 41, 页码: 127994
作者:  Wang,Jin-Ping;  Li,Tian-Ze;  Huang,Xiao-Yan;  Geng,Chang-An;  Shen,Cheng;  Sun,Jin-Jin;  Xue,Dong;  Chen,Ji-Jun
浏览  |  Adobe PDF(567Kb)  |  收藏  |  浏览/下载：130/40  |  提交时间：2022/04/02
Santamarin derivatives  Anti-fibrotic effects  HSC-LX2  Extracellular matrix  NF-KAPPA-B  SESQUITERPENE LACTONES  LIVER FIBROSIS  STRUCTURE REQUIREMENT  BAY LEAF  ACTIVATION  
A new sesquineolignan and four new neolignans isolated from the leaves of Piper betle, a traditional medicinal plant in Myanmar 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 31, 页码: 127682
作者:  San,Thae Thae;  Wang,Yue-Hu;  Hu,Dong-Bao;  Yang,Jun;  Zhang,Dong-Dong;  Xia,Meng-Yuan;  Yang,Xue-Fei;  Yang,Yong-Ping
浏览  |  Adobe PDF(1873Kb)  |  收藏  |  浏览/下载：157/44  |  提交时间：2022/04/02
Myanmar  Piper betle  Piperaceae  Neolignans  Anti-inflammatory  CHEMICAL-CONSTITUENTS  IN-VITRO  L.  PHENYLPROPANOIDS  IDENTIFICATION  COMPONENTS  ROOTS  OIL  
Synthesis and biological evaluation of novel 3-benzylcoumarin-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 4, 页码: 6
作者:  Wang, Xue-Quan;  Chen, Xue-Bing;  Ye, Ping-Ting;  Yang, Zhi-Xin;  Bai, Meng-Jiao;  Duan, Su-Yue;  Li, Yan;  Yang, Xiao-Dong
收藏  |  浏览/下载：274/0  |  提交时间：2020/03/18
3-Benzylcoumarin  Imidazolium salts  Biological evaluation  Cytotoxic activity  Structure-activity relationships  
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载：229/0  |  提交时间：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Synthesis and biological activity of new bisbenzofuran-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020
作者:  Wang, Xue-Quan;  Ye, Ping-Ting;  Bai, Meng-Jiao;  Miu, Wei-Hang;  Yang, Zhi-Xin;  Duan, Su-Yue;  Li, Tian-Tian;  Li, Yan;  Yang, Xiao-Dong
浏览  |  Adobe PDF(2161Kb)  |  收藏  |  浏览/下载：258/33  |  提交时间：2021/01/05
Synthesis and biological evaluation of chepraecoxin A derivatives as alpha-glucosidase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020
作者:  Yang, Xiao-Tong;  Geng, Chang-An;  Li, Tian-Ze;  Deng, Zhen-Tao;  Chen, Ji-Jun
浏览  |  Adobe PDF(675Kb)  |  收藏  |  浏览/下载：307/33  |  提交时间：2021/01/05
Hypolipidemic constituents from the aerial portion of Sibiraea angustata 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020
作者:  Liu, Hongdong;  Zhang, Ting;  Jiang, Piao;  Zhu, Weifeng;  Yu, Songhua;  Liu, Yong;  Li, Bin;  Li, Fei
浏览  |  Adobe PDF(1300Kb)  |  收藏  |  浏览/下载：171/54  |  提交时间：2021/01/05
A Novel bis-indole Alkaloid from the Flowers of Rauvolfia yunnanensis Tsiang and its Antihypertension Activity 期刊论文
LETTERS IN ORGANIC CHEMISTRY, 2020, 卷号: 17, 期号: 2, 页码: 96-100
作者:  Wang, Haibo;  Liu, Xikui
收藏  |  浏览/下载：198/0  |  提交时间：2020/03/18
Alkaloid  Bis-indole alkaloid  Rauvolfia yunnanensis  rauvolfia flowers  antihypertension  reserpine