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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
作者:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  收藏  |  浏览/下载：279/1  |  提交时间：2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
作者:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  收藏  |  浏览/下载：182/1  |  提交时间：2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase-9 through modulation of NF-B and AP-1 activity in human liver cancer cells lines 期刊论文
出版物, 3111, 期号: 0, 页码: 1—28
作者:  Ming-Ju Hsieh;  Chiao-Wen Lin;  Shun-Fa Yang;  Mu-Kuan Chen;  Hui-Ling Chiou
Adobe PDF(1320Kb)  |  收藏  |  浏览/下载：183/1  |  提交时间：2017/07/24
Glabridin  Migration  Invasion  Matrix Metalloproteinase-9  Hepatoma  
YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
作者:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
Adobe PDF(1357Kb)  |  收藏  |  浏览/下载：310/1  |  提交时间：2017/07/24
Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
Effects of CO-RM2 on LPS-induced vascular cell adhesion molecule-1 expression and leukocyte adhesion in human rheumatoid synovial fibroblasts 期刊论文
出版物, 3111, 期号: 0, 页码: 1-44
作者:  Pei-Ling Chi;  Yu-Chen Chuang;  Yu-Wen Chen;  Chih-Chung Lin;  Li-Der Hsiao;  Chuen-Mao Yang
Adobe PDF(1319Kb)  |  收藏  |  浏览/下载：181/1  |  提交时间：2017/07/24
Carbon Monoxide  Lipopolysaccharide  Vcam-1  Leukocyte Adhesion  
New Phenolic Dimers from Plant Paeonia suffruticosa and Their Cytotoxicity and NO Production Inhibition 期刊论文
Molecules, 2023
作者:  Qianqian Meng;  Shunyao Tong;  Yuqing Zhao;  Xingrong Peng;  Zhenghui Li;  Tao Feng;  Jikai Liu
Adobe PDF(1414Kb)  |  收藏  |  浏览/下载：429/60  |  提交时间：2023/10/07
Artemongolins A-K, undescribed germacrane-guaiane sesquiterpenoid dimers from Artemisia mongolica and their antihepatoma activities 期刊论文
ARCHIVES OF PHARMACAL RESEARCH, 2023, 卷号: 46, 期号: 9-10, 页码: 782-794
作者:  Shang,Chong;  Ma,Yun-Bao;  Wang,Yuan;  He,Xiao-Feng;  Li,Tian-Ze;  Chen,Ji-Jun
Adobe PDF(1281Kb)  |  收藏  |  浏览/下载：10/3  |  提交时间：2024/05/09
Artemisia mongolica  Artemongolins A-K  Sesquiterpenoid dimers  Antihepatoma activity  HEPATOCELLULAR-CARCINOMA  LACTONE  ARGYI  
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 886
作者:  Chen,Yuanzhi;  He,Zhicheng;  Yang,Shuting;  Chen,Cheng;  Xiong,Wenyong;  He,Yingying;  Liu,Shubai
Adobe PDF(4466Kb)  |  收藏  |  浏览/下载：6/0  |  提交时间：2024/05/09
Runt-related transcription factor 1 (RUNX1)  High-grade serous ovarian carcinoma (HGSOC)  Apoptosis  EMT  Clinical therapeutic target  EPITHELIAL-MESENCHYMAL TRANSITIONS  HEPATOCELLULAR-CARCINOMA  TRANSCRIPTION FACTOR  TP53 MUTATIONS  UP-REGULATION  TUMOR-GROWTH  MIGRATION  PROLIFERATION  INVASION  FOXO1  
Cytotoxic and pro-apoptotic effects of botanical drugs derived from the indigenous cultivated medicinal plant Paris polyphylla var. yunnanensis 期刊论文
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1100825
作者:  Yan,Xiu-Xiang;  Zhao,Yan-Qiang;  He,Yun;  Disayathanoowat,Terd;  Pandith,Hataichanok;  Inta,Angkhana;  Yang,Li-Xin
浏览  |  Adobe PDF(3195Kb)  |  收藏  |  浏览/下载：5/1  |  提交时间：2024/05/09
Paris polyphylla var  yunnanensis  indigenous medicine knowledge  saponins  cytotoxic effects  pro-apoptotic effects  CELL-CYCLE ARREST  STEROIDAL SAPONINS  HEPATOCELLULAR-CARCINOMA  CHEMICAL-CONSTITUENTS  ASSAY  GLYCOSIDES  LEAVES  GROWTH  STEMS  SITES  
多花蒿中流份 B 和 E 的抗肝癌活性成分研究 学位论文
: 中国科学院大学, 2022
作者:  张鑫
Adobe PDF(3975Kb)  |  收藏  |  浏览/下载：0/0  |  提交时间：2024/05/14
多花蒿，多花蒿素 A~L，吉玛烷型倍半萜，抗肝癌细胞毒活性  Artemisia myriantha, artemyrianosins A~L, germacrane sesquiterpenoids, antihepatoma activity