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Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Li, Ning;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
收藏  |  浏览/下载：210/0  |  提交时间：2018/07/16
Acetyl-macrocalin B  reactive oxygen species  p38 MAPK  apoptosis  Chk1  Chk2  G2  M phase arrest  NSCLC  
Efficient Semisynthesis of (-)-Pseudoirroratin A from (-)-Flexicaulin A and Assessment of Their Antitumor Activities 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 8, 期号: 3, 页码: 372-376
作者:  Guo, Lei;  Tsang, Siu Wai;  Zhang, Tong-Xin;  Liu, Kang-Lun;  Guan, Yi-Fu;  Wang, Bo;  Sun, Han-Dong;  Zhang, Hong-Jie;  Wong, Man Shing
浏览  |  Adobe PDF(1840Kb)  |  收藏  |  浏览/下载：219/40  |  提交时间：2017/05/19
(-)-pseudoirroratin a  (-)-flexicaulin a  Apoptosis  Antitumor Activity  
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi;  Li, Yan
浏览  |  Adobe PDF(3014Kb)  |  收藏  |  浏览/下载：280/71  |  提交时间：2015/06/17
Erib  Activity-based Probes  P50  Nf-kappa b Signaling  Apoptosis  
Anti-tumour activity of longikaurin A (LK-A), a novel natural diterpenoid, in nasopharyngeal carcinoma 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2013, 卷号: 11, 期号: 1, 页码: 200
作者:  Zou, Qing-Feng;  Du, Ji-Ke;  Zhang, Hua;  Wang, Hong-Bo;  Hu, Ze-Dong;  Chen, Shu-Peng;  Du, Yong;  Li, Man-Zhi;  Xie, Dan;  Zou, Juan;  Sun, Han-Dong;  Pu, Jian-Xin;  Zeng, Mu-Sheng
浏览  |  Adobe PDF(3788Kb)  |  收藏  |  浏览/下载：285/42  |  提交时间：2013/10/16
Longikaurin a (Lk-a)  Apoptosis  Caspase  Nasopharyngeal Carcinoma  
Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 卷号: 262, 期号: 1, 页码: 80-90
作者:  Li, Lin;  Yue, Grace G. L.;  Lau, Clara B. S.;  Sun, Handong;  Fung, Kwok Pui;  Leung, Ping Chung;  Han, Quanbin;  Leung, Po Sing
Adobe PDF(2066Kb)  |  收藏  |  浏览/下载：282/62  |  提交时间：2014/04/02
Eriocalyxin b  Pancreatic Cancer  Apoptosis  Cell Cycle Arrest  P53  
Quick identification of apoptosis inducer from Isodon eriocalyx by a drug discovery platform composed of analytical high-speed counter-current chromatography and the fluorescence-based caspase-3 biosensor detection 期刊论文
TALANTA, 2010, 卷号: 82, 期号: 4, 页码: 1521-1527
作者:  Han, Quan-Bin;  Yu, Ting;  Lai, Fanny;  Zhou, Yan;  Feng, Chao;  Wang, Wei-Na;  Fu, Xiao-Hui;  Lau, Clara Bik-San;  Luo, Kathy Q.;  Xu, Hong-Xi;  Sun, Han-Dong;  Fung, Kwok-Pui;  Leung, Ping-Chung
Adobe PDF(487Kb)  |  收藏  |  浏览/下载：338/131  |  提交时间：2012/03/21
Analytical High-speed Counter-current Chromatography  Caspase-3 Biosensor  Isodon Eriocalyx  Apoptosis Inducer  Eriocalyxin b  
Electrospray tandem mass spectrometry of longipedlactone triterpenoids 期刊论文
JOURNAL OF MASS SPECTROMETRY, 2010, 卷号: 45, 期号: 4, 页码: 451-455
作者:  Wu, Zhi-Jun;  Pu, Jian-Xin;  Li, Li-Mei;  Fang, Dong-Mei;  Qi, Hua-Yi;  Chen, Jian-Zhong;  Li, Guo-You;  Sun, Han-Dong;  Zhang, Guo-Lin
Adobe PDF(193Kb)  |  收藏  |  浏览/下载：362/79  |  提交时间：2012/03/21
Onosma Paniculatum  Zicao  Cancer  Cell Cycle  Caspase-3  Traditional Chinese Medicine  Naphthoquinone Derivatives  Induced Apoptosis  Natural-products  Cancer-therapy  In-vitro  Shikonin  Dna  Pharmacogenomics  Induction  
A pair of novel cytotoxic polyprenylated xanthone epimers from gamboges 期刊论文
CHEMISTRY & BIODIVERSITY, 2006, 卷号: 3, 期号: 1, 页码: 101-105
作者:  Han, QB;  Yang, L;  Wang, YL;  Qiao, CF;  Song, JZ;  Sun, HD;  Xu, HX
Adobe PDF(289Kb)  |  收藏  |  浏览/下载：242/91  |  提交时间：2011/11/24
Garcinia-hanburyi  In-vitro  Acid  Cells  Proliferation  Apoptosis  Assay  
Scavenging of reactive oxygen species and prevention of oxidative neuronal cell damage by a novel gallotannin, Pistafolia A 期刊论文
LIFE SCIENCES, 2002, 卷号: 70, 期号: 16, 页码: 1889-1899
作者:  Wei, TT;  Sun, HD;  Zhao, XY;  Hou, JW;  Hou, AJ;  Zhao, QS;  Xin, WJ
Adobe PDF(166Kb)  |  收藏  |  浏览/下载：261/57  |  提交时间：2012/07/25
Pistafolia a  Gallotannin  Free Radical  Cerebellar Granule Cell  Oxidative Stress  Apoptosis