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Catalyzed Synthesis of 3-hydroxy-indol-2-one Derivatives as a Novel Phosphodiesterases 10 Inhibitor 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2020, 卷号: 126, 页码: 33-34
作者:  Wu, Ya;  Li, Hao;  Yan, Jiao;  Cai, Qing;  Huang, Shengxiong;  Tang, Ying;  Ji, Yue;  Hao, Xiaojiang;  Chen, Gang
收藏  |  浏览/下载：203/0  |  提交时间：2020/03/24
Polycyclic polyprenylated acylphloroglucinol derivatives with neuroprotective effects from Hypericum monogynum 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 页码: 9
作者:  Zeng, Yan-Rong;  Li, Ya-Na;  Lou, Hua-Yong;  Jian, Jun-You;  Gu, Wei;  Huang, Lie-Jun;  Du, Guan-Hua;  Yuan, Chun-Mao;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1233Kb)  |  收藏  |  浏览/下载：233/37  |  提交时间：2020/03/18
Hypericum monogynum  polycyclic polyprenylated acylphloroglucinols (PPAPs)  neuroprotective effects  structure-activity relationship  
Melocochines A and B, Two Alkaloids from the Fruits of Melodinus cochinchinensis 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 22, 页码: 9272-9275
作者:  Zhang, Yu;  Ding, Xiao;  Shao, Shun;  Guo, Ling-Li;  Zhao, Qing;  Hao, Xiao-Jiang;  He, Hong-Ping
浏览  |  Adobe PDF(982Kb)  |  收藏  |  浏览/下载：293/158  |  提交时间：2020/03/02
Cytotoxic phenolic constituents from Hypericum japonicum 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 164, 页码: 33-40
作者:  Zhu, Wei;  Qiu, Jie;  Zeng, Yan-Rong;  Yi, Ping;  Lou, Hua-Yong;  Jian, Jun-You;  Zuo, Ming-Xing;  Duan, Lian;  Gu, Wei;  Huang, Lie-Jun;  Li, Yan-Mei;  Yuan, Chun-Mao;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(902Kb)  |  收藏  |  浏览/下载：381/171  |  提交时间：2019/09/10
Hypericum japonicum thunb. (Hypericaceae)  Phenolic compounds  Xanthone and flavonoid derivatives  Cytotoxic activities  Structure-activity relationship  
Design, synthesis, and cytotoxic activities of novel hybrids of parthenolide and thiazolidinedione via click chemistry 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 页码: 9
作者:  Qiu, Jie;  Yuan, Chun-Mao;  Wen, Min;  Li, Ya-Nan;  Chen, Juan;  Jian, Jun-You;  Huang, Lie-Jun;  Gu, Wei;  Li, Yan-Mei;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1093Kb)  |  收藏  |  浏览/下载：199/48  |  提交时间：2019/07/29
Parthenolide-thiazolidinedione hybrids  click chemistry  cytotoxic activities  
Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 7, 页码: 10
作者:  Zhang, Yu;  Goto, Masuo;  Oda, Akifumi;  Hsu, Pei-Ling;  Guo, Ling-Li;  Fu, Yan-Hui;  Morris-Natschke, Susan L.;  Hamel, Ernest;  Lee, Kuo-Hsiung;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3129Kb)  |  收藏  |  浏览/下载：214/23  |  提交时间：2019/07/29
aspidosperma-type  monoterpenoid indole alkaloids  antiproliferative activity  tubulin inhibitor  Bousigonia mekongensis  
Nukiangendines A and B, two novel 13,14-seco-abietanes from Abies nukiangensis 期刊论文
TETRAHEDRON LETTERS, 2019, 卷号: 60, 期号: 10, 页码: 751-753
作者:  Li, Yong-Li;  Zhang, Qiang;  Wu, Jian-Jun;  Xue, Li-Jun;  Chen, Li-Ming;  Tian, Jun-Mian;  Xu, Zhuo-Ni;  Chen, Ying;  Yang, Xian-Wen;  Hao, Xiao-Jiang;  Li, Jie
浏览  |  Adobe PDF(561Kb)  |  收藏  |  浏览/下载：239/30  |  提交时间：2019/04/15
Abies nukiangensis  seco-Abietane  Diterpene  Antiviral  
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：312/37  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 11
作者:  Liu, Tangjingjun;  Xia, Lei;  Yao, Yao;  Yan, Chen;  Fan, Yanhua;  Gajendran, Babu;  Yang, Jue;  Li, You-Jun;  Chen, Juan;  Filmus, Jorge;  Spaner, David E.;  Zacksenhaus, Eldad;  Hao, Xiaojiang;  Ben-David, Yaacov
浏览  |  Adobe PDF(2055Kb)  |  收藏  |  浏览/下载：269/37  |  提交时间：2019/04/15
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
浏览  |  Adobe PDF(2607Kb)  |  收藏  |  浏览/下载：280/47  |  提交时间：2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest