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Cangumycins A-F, six new angucyclinone analogues with immunosuppressive activity from Streptomyces 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 982-987
作者:  Wang Lei;  Wang Li;  Zhou Zhi;  Wang Yong-Jiang;  Huang Jian-Ping;  Ma Ya-Tuan;  Liu Yang;  Huang Sheng-Xiong
浏览  |  Adobe PDF(563Kb)  |  收藏  |  浏览/下载：173/33  |  提交时间：2020/03/18
Streptomyces  Angucyclinones  Benz[a]anthracenes  Natural products  Immunosuppressive activity  
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：206/31  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Precise structures and anti-intrinsic tenase complex activity of three fucosylated glycosaminoglycans and their fragments 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 224, 页码: 10
作者:  Cai, Ying;  Yang, Wenjiao;  Li, Xiaomei;  Zhou, Lutan;  Wang, Zhongjuan;  Lin, Lisha;  Chen, Dingyuan;  Zhao, Longyan;  Li, Zhongkun;  Liu, Shubai;  Yin, Ronghua;  Zuo, Zhili;  Gao, Na;  Zhao, Jinhua
浏览  |  Adobe PDF(4714Kb)  |  收藏  |  浏览/下载：339/44  |  提交时间：2019/10/28
Fucosylated glycosaminoglycan  Oligosaccharide  Chemical structure  iXase  
Design and synthesis of novel artemisinin derivatives with potent activities against colorectal cancer in vitro and in vivo 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 182, 页码: 10
作者:  Wang, Liang-Liang;  Kong, Lingmei;  Liu, Hui;  Zhang, Yunqin;  Zhang, Li;  Liu, Xingyong;  Yuan, Feng;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载：135/0  |  提交时间：2020/03/02
Artemisinin  Quinazoline  Hybridization  Colorectal cancer  Chemotherapy  
C30 and C31 Triterpenoids and Triterpene Sugar Esters with Cytotoxic Activities from Edible Mushroom Fomitopsis pinicola (Sw. Ex Fr.) Krast 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 37, 页码: 10330-10341
作者:  Peng, Xing-Rong;  Su, Hai-Guo;  Liu, Jun-Hong;  Huang, Yan-Jie;  Yang, Xin-Zhi;  Li, Zhong-Rong;  Zhou, Lin;  Qiu, Ming-Hua
Adobe PDF(1422Kb)  |  收藏  |  浏览/下载：217/66  |  提交时间：2019/11/07
Polyporaceae  Fomitopsis pinicola  C30 triterpenoids  C31 triterpenoids  cytotoxic activity  
Anti-inflammatory Effect of Pomelo Peel and Its Bioactive Coumarins 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 32, 页码: 8810-8818
作者:  Zhao, Yun-Li;  Yang, Xiong-Wu;  Wu, Bai-Fen;  Shang, Jian-Hua;  Liu, Ya-Ping;  Zhi-Dai;  Luo, Xiao-Dong
Adobe PDF(1099Kb)  |  收藏  |  浏览/下载：170/48  |  提交时间：2019/10/14
C. grandis  coumarins  anti-inflammatory effect  lipopolysaccharide  
Identification of novel monoamine oxidase selective inhibitors employing a hierarchical ligand-based virtual screening strategy 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 8, 页码: 801-816
作者:  Wang, Dong;  Li, Zhaoyang;  Liu, Yi;  Chen, Mo;  Chen, Nianhang;  Zuo, Zhili;  Kong, De-Xin
浏览  |  Adobe PDF(1462Kb)  |  收藏  |  浏览/下载：177/36  |  提交时间：2019/09/10
BRS-3D  monoamine oxidase selective inhibitors  virtual screening  
Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 79, 页码: 165-176
作者:  Li, Yingying;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Liu, Xingyong;  Zhang, Li;  Wang, Liang-Liang;  Zuo, Zhili
浏览  |  Adobe PDF(7335Kb)  |  收藏  |  浏览/下载：250/27  |  提交时间：2019/07/29
Pharmacophore modeling  Molecular docking  Quantitative structure activity relationship (QSAR)  Molecular dynamics  AMPK  Activator  
Prevalence of isomeric plastomes and effectiveness of plastome super-barcodes in yews (Taxus) worldwide 期刊论文
SCIENTIFIC REPORTS, 2019, 卷号: 9, 页码: 11
作者:  Fu, Chao-Nan;  Wu, Chung-Shien;  Ye, Lin-Jiang;  Mo, Zhi-Qiong;  Liu, Jie;  Chang, Yu-Wen;  Li, De-Zhu;  Chaw, Shu-Miaw;  Gao, Lian-Ming
浏览  |  Adobe PDF(3412Kb)  |  收藏  |  浏览/下载：430/117  |  提交时间：2019/03/25
Discovery of novel indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors by virtual screening 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 78, 页码: 306-316
作者:  Zhou, Yeheng;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Li, Yingying;  Zhang, Li;  Sun, Wei;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(2732Kb)  |  收藏  |  浏览/下载：263/42  |  提交时间：2019/03/25
IDO1  Molecular docking  HipHop pharmacophore  3D-QSAR  PAINS