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Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：231/36  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Star-PAP regulates tumor protein D52 through modulating miR-449a/34a in breast cancer 期刊论文
BIOLOGY OPEN, 2019, 卷号: 8, 期号: 11, 页码: 9
作者:  Duan, Aizhu;  Kong, Lingmei;  An, Tao;  Zhou, Hongyu;  Yu, Chunlei;  Li, Yan
浏览  |  Adobe PDF(2302Kb)  |  收藏  |  浏览/下载：313/68  |  提交时间：2020/03/02
Star-PAP  TPD52  miR-449a  miR-34a  Breast cancer  
12 beta-Acetyloxyperforatin, a New Limonoid from Harrisonia Perforata 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 卷号: 33, 期号: 19, 页码: 2830-2836
作者:  Gui, Peng-Yan;  Yan, Xiao-Hui;  Yuan, Wen-Juan;  Ma, Yuan-Liang;  Ding, Xiao;  Liu, Shuai;  Di, Ying-Tong;  Zhu, Wei-Ming;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(919Kb)  |  收藏  |  浏览/下载：404/178  |  提交时间：2019/09/10
Harrisonia perforata  limonoid  12 beta-Acetyloxyperforatin  computational modelling  
Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(9057Kb)  |  收藏  |  浏览/下载：262/51  |  提交时间：2020/03/26
Anti-BACE1 and anti-AchE activities of undescribed spiro-dioxolane-containing meroterpenoids from the endophytic fungus Aspergillus terreus Thom 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 165, 页码: 8
作者:  Qi, Changxing;  Zhou, Qun;  Gao, Weixi;  Liu, Mengting;  Chen, Chunmei;  Li, Xiao-Nian;  Lai, Yongji;  Zhou, Yuan;  Li, Dongyan;  Hu, Zhengxi;  Zhu, Hucheng;  Zhang, Yonghui
浏览  |  Adobe PDF(1128Kb)  |  收藏  |  浏览/下载：314/158  |  提交时间：2019/10/14
Aspergillus terreus Thom  endophytic fungus  3,5-Dimethylorsellinic acid-based meroterpenoid  Adducts  Alzheimer's disease  
Blocking ROR1 enhances the roles of erlotinib in lung adenocarcinoma cell lines 期刊论文
ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 3, 页码: 2977-2984
作者:  Wang, Hui-Li;  Liu, Yan-Chun;  Long, Ming-Peng;  Zheng, Chuan;  Yang, Jia-Hui
浏览  |  Adobe PDF(667Kb)  |  收藏  |  浏览/下载：184/52  |  提交时间：2019/11/07
receptor tyrosine kinase-like orphan receptor 1  lung adenocarcinoma  erlotinib resistance  AKT  mammalian target of rapamycin  small interfering RNA  
Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin 期刊论文
CELL CHEMICAL BIOLOGY, 2019, 卷号: 26, 期号: 8, 页码: 1122-+
作者:  Zhu, Huifang;  Wang, Bin;  Kong, Lingmei;  An, Tao;  Li, Gentao;  Zhou, Hongyu;  Gong, Liang;  Zhao, Zhangxun;  Gong, Yaxiao;  Sun, Handong;  Puno, Pematenzin;  Li, Yan
浏览  |  Adobe PDF(4600Kb)  |  收藏  |  浏览/下载：221/40  |  提交时间：2019/10/14
Anti-inflammatory Effect of Pomelo Peel and Its Bioactive Coumarins 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 32, 页码: 8810-8818
作者:  Zhao, Yun-Li;  Yang, Xiong-Wu;  Wu, Bai-Fen;  Shang, Jian-Hua;  Liu, Ya-Ping;  Zhi-Dai;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1099Kb)  |  收藏  |  浏览/下载：197/56  |  提交时间：2019/10/14
C. grandis  coumarins  anti-inflammatory effect  lipopolysaccharide  
Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity 期刊论文
BMC Cancer, 2019, 卷号: 19, 期号: 1
作者:  Wang,Ning;  Fan,Yanhua;  Yuan,Chun-Mao;  Song,Jialei;  Yao,Yao;  Liu,Wuling;  Gajendran,Babu;  Zacksenhaus,Eldad;  Li,Yanmei;  Liu,Jielin;  Hao,Xiao Jiang;  Ben-David,Yaacov
收藏  |  浏览/下载：162/0  |  提交时间：2019/08/13
Cancer  Leukemia  Chinese medicinal plant  Melia azedarach  Drug screen  ERK1/2 agonists  Differentiation  Apoptosis  
Ensemble docking-based virtual screening toward identifying inhibitors against Wee1 kinase 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 15, 页码: 1889-1906
作者:  Li, Yaping;  Wu, Dong-mei;  Kong, Ling-mei;  Zhang, Shuqun;  Du, Haibo;  Sun, Wei;  Zhang, Li;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载：184/0  |  提交时间：2020/03/26
bioassay  ensemble docking  scoring function  virtual screening  Wee1 inhibitors