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Nonasaccharide Inhibits Intrinsic Factor Xase Complex by Binding to Factor IXa and Disrupting Factor IXa-Factor VIIIa Interactions 期刊论文
THROMBOSIS AND HAEMOSTASIS, 2019, 卷号: 119, 期号: 5, 页码: 705-715
作者:  Xiao, Chuang;  Zhao, Longyan;  Gao, Na;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(740Kb)  |  收藏  |  浏览/下载：253/69  |  提交时间：2019/06/24
nonasaccharide from fucosylated glycosaminoglycan  intrinsic factor Xase complex  factor IXa  anticoagulant  
Structural analysis and anticoagulant activities of three highly regular fucan sulfates as novel intrinsic factor Xase inhibitors 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 195, 页码: 257-266
作者:  Shang, Feineng;  Mou, Rongrong;  Zhang, Zhidong;  Gao, Na;  Lin, Lisha;  Li, Zhongkun;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(2021Kb)  |  收藏  |  浏览/下载：352/67  |  提交时间：2018/07/16
Fucan Sulfate  Chemical Structure  Anticoagulant  Polysaccharide  Sea Cucumber  
Precise structures of fucosylated glycosaminoglycan and its oligosaccharides as novel intrinsic factor Xase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 423-435
作者:  Shang, Feineng;  Gao, Na;  Yin, Ronghua;  Lin, Lisha;  Xiao, Chuang;  Zhou, Lutan;  Li, Zi;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(3117Kb)  |  收藏  |  浏览/下载：274/82  |  提交时间：2018/05/08
Glycosaminoglycan  Oligosaccharide  Anticoagulant  Intrinsic Factor Xase  
Enzyme-Assisted Extraction Optimization, Characterization and Antioxidant Activity of Polysaccharides from Sea Cucumber Phyllophorus proteus 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3, 页码: 590
作者:  Qin, Yujing;  Yuan, Qingxia;  Zhang, Yuexing;  Li, Jialu;  Zhu, Xinjiao;  Zhao, Lingling;  Wen, Jing;  Liu, Jikai;  Zhao, Longyan;  Zhao, Jinhua
浏览  |  Adobe PDF(5270Kb)  |  收藏  |  浏览/下载：282/74  |  提交时间：2018/07/02
Sea Cucumber  Polysaccharide  Enzyme-assisted Extraction  Characterization  Antioxidant Activity  
Discovery of an intrinsic tenase complex inhibitor: Pure nonasaccharide from fucosylated glycosaminoglycan 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 卷号: 112, 期号: 27, 页码: 8284-8289
作者:  Zhao, Longyan;  Wu, Mingyi;  Xiao, Chuang;  Yang, Lian;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Chen, Jun;  Chen, Jianchao;  Liu, Jikai;  Qin, Hongbo;  Zhao, Jinhua
浏览  |  Adobe PDF(1067Kb)  |  收藏  |  浏览/下载：331/44  |  提交时间：2015/12/17
Anticoagulant  Inhibitors  Oligosaccharides  Carbohydrates  Drug Discovery  
Anticoagulant and antithrombotic evaluation of native fucosylated chondroitin sulfates and their derivatives as selective inhibitors of intrinsic factor Xase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 92, 页码: 257-269
作者:  Wu, Mingyi;  Wen, Dandan;  Gao, Na;  Xiao, Chuang;  Yang, Lian;  Xu, Li;  Lian, Wu;  Peng, Wenlie;  Jiang, Jianmin;  Zhao, Jinhua;  Jiang,JM (reprint author),Sun Yat Sen Univ,Sch Pharmaceut Sci,Guangzhou 510006,Guangdong,Peoples R China.;  lssjjm@mail.sysu.edu.cn;  zhao.jinhua@yahoo.com
浏览  |  Adobe PDF(1936Kb)  |  收藏  |  浏览/下载：344/109  |  提交时间：2015/06/29
Fucosylated Chondroitin Sulfate  Factor Xase Inhibitor  Anticoagulant  Antithrombotic  Structure-activity Relationship  
Structural Analysis and Anticoagulant Activities of the Novel Sulfated Fucan Possessing a Regular Well-Defined Repeating Unit from Sea Cucumber 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 4, 页码: 2063-2084
作者:  Wu, Mingyi;  Xu, Li;  Zhao, Longyan;  Xiao, Chuang;  Gao, Na;  Luo, Lan;  Yang, Lian;  Li, Zi;  Chen, Lingyun;  Zhao, Jinhua
浏览  |  Adobe PDF(2239Kb)  |  收藏  |  浏览/下载：310/60  |  提交时间：2015/06/29
Preparation and Characterization of O-Acylated Fucosylated Chondroitin Sulfate from Sea Cucumber 期刊论文
MARINE DRUGS, 2012, 卷号: 10, 期号: 8, 页码: 1647-1661
作者:  Gao, Na;  Wu, Mingyi;  Liu, Shao;  Lian, Wu;  Li, Zi;  Zhao, Jinhua
Adobe PDF(1048Kb)  |  收藏  |  浏览/下载：421/86  |  提交时间：2012/11/30
Sea Cucumber  Fucosylated Chondroitin Sulfate  Glycosaminoglycan  Acylation  Anticoagulant Activity