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Effects of a new advanced glycation inhibitor, LR-90, on mitigating arterial stiffening and improving arterial elasticity and compliance in a diabetic rat model: aortic impedance analysis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-33
作者:  S, Satheesan;  J L, Figarola;  T, Dabbs;  S, Rahbar;  R, Ermel
Adobe PDF(967Kb)  |  收藏  |  浏览/下载：273/1  |  提交时间：2017/07/24
Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol derivatives as alpha-glucosidase and PTP1B inhibitors 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 2, 页码: 350-367
作者:  Yang, Xiao-Tong;  Li, Tian-Ze;  Geng, Chang-An;  Liu, Pei;  Chen, Ji-Jun
Adobe PDF(1348Kb)  |  收藏  |  浏览/下载：32/8  |  提交时间：2024/04/30
(20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol  alpha-glucosidase inhibitors  PTP1B inhibitors  Enzyme kinetics  TYROSINE-PHOSPHATASE 1B  DIABETES-MELLITUS  EPIDEMIOLOGY  
Bitter Melon and Diabetes Mellitus 期刊论文
FOOD REVIEWS INTERNATIONAL, 2021
作者:  Gao,Ya;  Li,Xian;  Huang,Yanjie;  Chen,Jianchao;  Qiu,Minghua
收藏  |  浏览/下载：67/0  |  提交时间：2022/04/02
Bitter melon  diabetes mellitus  crude extracts  phyto-metabolites  hypoglycemic mechanism  MOMORDICA-CHARANTIA L.  11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1  ALPHA-GLUCOSIDASE INHIBITION  INSULIN-RESISTANCE  ANTIDIABETIC ACTIVITIES  GUT MICROBIOTA  STRUCTURAL-CHARACTERIZATION  PHENOLIC-COMPOUNDS  OXIDATIVE STRESS  PROTEIN-KINASE  
Novel Signature Genes and Pathways Identified for Human Left Ventricle Cardiomyopathies Rise from different Etiologies 期刊论文
Journal of Biomedical Research and Reviews, 2021
作者:  Jiao Tian;  Zheng Yuan Wu;  Ying Ying He;  Shubai Liu
浏览  |  Adobe PDF(1819Kb)  |  收藏  |  浏览/下载：57/18  |  提交时间：2023/09/08
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Huang,Xiao-Yan;  Zhang,Xue-Mei;  Guo,Yuan-Qiang;  Geng,Chang-An
浏览  |  Adobe PDF(2762Kb)  |  收藏  |  浏览/下载：141/59  |  提交时间：2022/04/02
Alpinia katsumadai  Katsumadainols B-1-B-15  Natural products  Structure elucidation  Biological activity  TYROSINE-PHOSPHATASE 1B  GLYCOGEN-PHOSPHORYLASE  ALPHA-GLUCOSIDASE  ABSOLUTE-CONFIGURATION  STRUCTURE ELUCIDATION  DUAL INHIBITION  SEEDS  CONSTITUENT  DERIVATIVES  CHALCONE  
Chemical profiling and antidiabetic potency of Paeonia delavayi: Comparison between different parts and constituents 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 113998
作者:  Huang,Qian;  Chen,Ji-Jun;  Pan,Yang;  He,Xiao-Feng;  Wang,Yuan;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(2388Kb)  |  收藏  |  浏览/下载：69/10  |  提交时间：2022/04/02
Paeonia delavayi  Chemical comparison  LCMS analyses  Antidiabetic effects  PTP1B/TCPTP selective inhibitors  LIQUID-CHROMATOGRAPHY  MULTIPLE CONSTITUENTS  RAPID IDENTIFICATION  GLYCOSIDES  ROOT  DERIVATIVES  TARGETS  CAPSULE  L.  
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(5184Kb)  |  收藏  |  浏览/下载：92/24  |  提交时间：2022/04/02
Amomum tsao-ko  Amomutsaokins A-H  Flavanol-menthane conjugates  PTP1B selective inhibitors  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  TANNINS  CREVOST  ACID  
Diarylheptanoid-chalcone hybrids with PTP1B and alpha-glucosidase dual inhibition from Alpinia katsumadai 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104683
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(2223Kb)  |  收藏  |  浏览/下载：130/53  |  提交时间：2022/04/02
Alpinia katsumadai  Katsumadainols A(1)-A(16)  PTP1B/TCPTP selective inhibitors  alpha-glucosidase inhibitors  Antidiabetic effects  THEORETICAL CALCULATION  ABSOLUTE-CONFIGURATION  SEEDS  BLEPHAROCALYXINS  ADDUCT  MOIETY  
Vincan- and eburnan-type alkaloids from Tabernaemontana bovina and their hypoglycemic activity 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 190, 页码: 112859
作者:  Yu,Yang;  Bao,Mei-Fen;  Huang,Sheng-Zhuo;  Wu,Jing;  Cai,Xiang-Hai
浏览  |  Adobe PDF(5274Kb)  |  收藏  |  浏览/下载：144/47  |  提交时间：2022/04/02
Tabernaemontana bovina  Apocynaceae  Vincan-type alkaloids  Eburnan-type alkaloids  Hypoglycemic activity  INDOLE ALKALOIDS  
FPR2-based anti-inflammatory and anti-lipogenesis activities of novel meroterpenoid dimers from Ganoderma 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105338
作者:  Peng,Xing-Rong;  Wang,Qian;  Wang,Hui-Rong;  Hu,Kun;  Xiong,Wen-Yong;  Qiu,Ming-Hua
浏览  |  Adobe PDF(7004Kb)  |  收藏  |  浏览/下载：94/13  |  提交时间：2022/04/02
Ganoderma applanatum  Meroterpenoid dimers  Molecular docking  Anti-lipogenesis  FPR2-based inflammation  INDUCED INSULIN-RESISTANCE  ADIPOCYTE DIFFERENTIATION  OBESITY  INFLAMMATION  DEFICIENCY  MACROPHAGES  ACTIVATION  EXPRESSION  LIGAND  MICE