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Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：339/44  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 11
作者:  Liu, Tangjingjun;  Xia, Lei;  Yao, Yao;  Yan, Chen;  Fan, Yanhua;  Gajendran, Babu;  Yang, Jue;  Li, You-Jun;  Chen, Juan;  Filmus, Jorge;  Spaner, David E.;  Zacksenhaus, Eldad;  Hao, Xiaojiang;  Ben-David, Yaacov
浏览  |  Adobe PDF(2055Kb)  |  收藏  |  浏览/下载：283/40  |  提交时间：2019/04/15
Munronin O, a potential activator for plant resistance 期刊论文
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 2018, 卷号: 146, 页码: 13-18
作者:  Yan, Ying;  Tang, Lei;  Hu, Jiaqi;  Wang, Jianta;  Adelakun, Tiwalade Adegoke;  Yang, Dongqiong;  Di, Yingtong;  Zhang, Yu;  Hao, Xiaojiang
浏览  |  Adobe PDF(1146Kb)  |  收藏  |  浏览/下载：611/162  |  提交时间：2018/06/11
Limonoids  Munronia Henryi Harms  Tobacco Mosaic Virus  Antiviral Activity  Plant Resistance  
Integrating transcriptome and microRNA analysis identifies genes and microRNAs for AHO-induced systemic acquired resistance in N-tabacum 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 12504
作者:  Chen, Yongdui;  Dong, Jiahong;  Bennetzen, Jeffrey L.;  Zhong, Micai;  Yang, Jun;  Zhang, Jie;  Li, Shunlin;  Hao, Xiaojiang;  Zhang, Zhongkai;  Wang, Xuewen
浏览  |  Adobe PDF(3093Kb)  |  收藏  |  浏览/下载：353/68  |  提交时间：2017/10/23
Plant Innate Immunity  Acibenzolar-s-methyl  Flue-cured Tobacco  Salicylic-acid  Small Rnas  Stress Responses  Expression  Arabidopsis  Target  Mirna  
Anti-HIV Activities and Mechanism of 12-O-Tricosanoylphorbol-20-acetate, a Novel Phorbol Ester from Ostodes katharinae 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 9, 页码: 1498
作者:  Chen, Huan;  Zhang, Rong;  Luo, Rong-Hua;  Yang, Liu-Meng;  Wang, Rui-Rui;  Hao, Xiao-Jiang;  Zheng, Yong-Tang
浏览  |  Adobe PDF(1939Kb)  |  收藏  |  浏览/下载：215/42  |  提交时间：2017/10/23
Antiviral Agent  12-o-tricosanoylphorbol-20-acetate  Hiv  Vif  Apobec3g  Phorbol Ester  
Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/beta-catenin transcriptional activity 期刊论文
CELL DISCOVERY, 2017, 卷号: 3, 页码: 17003
作者:  He, Xiaoli;  Zhang, Wenjuan;  Yan, Chen;  Nie, Fen;  Li, Chen;  Liu, Xiaofen;  Fei, Cong;  Li, Shengdi;  Song, Xiaomin;  Jia, Yingying;  Zeng, Rong;  Wu, Dianqing;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(3775Kb)  |  收藏  |  浏览/下载：162/42  |  提交时间：2017/12/18
Carf  Chemical Biology  Nc043  Small Molecule  Wnt Signaling  
Protein kinase C controls lysosome biogenesis independently of mTORC1 期刊论文
NATURE CELL BIOLOGY, 2016, 卷号: 18, 期号: 10, 页码: 1065-1077
作者:  Li, Yang;  Xu, Meng;  Ding, Xiao;  Yan, Chen;  Song, Zhiqin;  Chen, Lianwan;  Huang, Xiahe;  Wang, Xin;  Jian, Youli;  Tang, Guihua;  Tang, Changyong;  Di, Yingtong;  Mu, Shuzhen;  Liu, Xuezhao;  Liu, Kai;  Li, Ting;  Wang, Yingchun;  Miao, Long;  Guo, Weixiang;  Hao, Xiaojiang;  Yang, Chonglin
浏览  |  Adobe PDF(4637Kb)  |  收藏  |  浏览/下载：573/153  |  提交时间：2016/12/21
Design, Synthesis, and Structural Optimization of Lycorine-Derived Phenanthridine Derivatives as Wnt/beta-Catenin Signaling Pathway Agonists 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 1, 页码: 180-188
作者:  Chen, Duo-Zhi;  Jing, Chen-Xu;  Cai, Jie-Yun;  Wu, Ji-Bo;  Wang, Sheng;  Yin, Jun -Lin;  Li, Xiao-Nian;  Li, Lin;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3043Kb)  |  收藏  |  浏览/下载：326/77  |  提交时间：2016/06/27
Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction 期刊论文
NATURE CHEMICAL BIOLOGY, 2013, 卷号: 9, 期号: 9, 页码: 579-U82
作者:  Wang, Sheng;  Yin, Junlin;  Chen, Duozhi;  Nie, Fen;  Song, Xiaomin;  Fei, Cong;  Miao, Haofei;  Jing, Changbin;  Ma, Wenjing;  Wang, Lei;  Xie, Sichun;  Li, Chen;  Zeng, Rong;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
Adobe PDF(1157Kb)  |  收藏  |  浏览/下载：638/131  |  提交时间：2013/10/16
Glycogen-synthase Kinase-3  Beta-catenin  Negative Regulator  Dix Domain  Stem-cells  In-vivo  Axin  Activation  Pathway  Phosphorylation  
A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/beta-catenin signaling and colon cancer cell tumorigenesis 期刊论文
CELL RESEARCH, 2011, 卷号: 21, 期号: 5, 页码: 730-740
作者:  Wang, Wei;  Liu, Haiyang;  Wang, Sheng;  Hao, Xiaojiang;  Li, Lin
Adobe PDF(1539Kb)  |  收藏  |  浏览/下载：295/43  |  提交时间：2012/07/25
Wnt  Small Molecule  Inhibitor  Tumorigenesis