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Small compound bigelovin exerts inhibitory effects and triggers proteolysis of E2F1 in multiple myeloma cells 期刊论文
CANCER SCIENCE, 2013, 卷号: 104, 期号: 12, 页码: 1697-1704
作者:  Liu, Jing-Lei;  Zeng, Guang-Zhi;  Liu, Xiao-Li;  Liu, Yong-Qiang;  Hu, Zhong-Guo;  Liu, Ying;  Tan, Ning-Hua;  Zhou, Guang-Biao
浏览  |  Adobe PDF(1224Kb)  |  收藏  |  浏览/下载：205/52  |  提交时间：2015/05/13
A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2013, 卷号: 63, 期号: SI, 页码: 485-494
作者:  Liu, Jinhua;  Mu, Chenglong;  Yue, Wen;  Li, Jie;  Ma, Biao;  Zhao, Lixia;  Liu, Lei;  Chen, Quan;  Yan, Chen;  Liu, Haiyang;  Hao, Xiaojiang;  Zhu, Yushan
浏览  |  Adobe PDF(2679Kb)  |  收藏  |  浏览/下载：321/61  |  提交时间：2013/10/16
Thioredoxin Reductase  Bim  Ros  Apoptosis  Cancer  
Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2013, 卷号: 1830, 期号: 10, 页码: 4681-4691
作者:  Lian, Wu;  Wu, Mingyi;  Huang, Ning;  Gao, Na;  Xiao, Chuang;  Li, Zi;  Zhang, Zhigang;  Zheng, Yongtang;  Peng, Wenlie;  Zhao, Jinhua
Adobe PDF(2650Kb)  |  收藏  |  浏览/下载：483/96  |  提交时间：2013/11/12
Glycosaminoglycan  Anti-human Immunodeficiency Virus Activity  Envelope Glycoprotein 120  Cluster Of Differentiation 4 Induced Epitope  Biolayer Interferometry  Structure-activity Relationship  
Identification of two novel inhibitors of mTOR signaling pathway based on high content screening 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 卷号: 72, 期号: 4, 页码: 799-808
作者:  Yan, Juming;  Zhou, Hongyu;  Kong, Lingmei;  Zhang, Jing;  Zhao, Qinshi;  Li, Yan
Adobe PDF(1971Kb)  |  收藏  |  浏览/下载：690/107  |  提交时间：2013/11/12
Mtor Signaling  Inhibitor  High Content Screening  Cancer  Apoptosis  
Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntingtons disease 期刊论文
HUMAN MOLECULAR GENETICS, 2013, 卷号: 22, 期号: 18, 页码: 3641-3653
作者:  Wang, Fengli;  Yang, Yeran;  Lin, Xiwen;  Wang, Jiu-Qiang;  Wu, Yong-Sheng;  Xie, Wenjuan;  Wang, Dandan;  Zhu, Shu;  Liao, You-Qi;  Sun, Qinmiao;  Yang, Yun-Gui;  Luo, Huai-Rong;  Guo, Caixia;  Han, Chunsheng;  Tang, Tie-Shan
浏览  |  Adobe PDF(1710Kb)  |  收藏  |  浏览/下载：311/62  |  提交时间：2013/10/16
Embryonic Stem-cells  Adult Hippocampal Neurogenesis  Transgenic Mouse Model  Dna Methylation  Gene-expression  Mutant Huntingtin  Nervous-system  Polyglutamine Pathogenesis  Mitochondrial Dysfunction  Mammalian Development  
Antiproliferative Cardiac Glycosides from the Latex of Antiaris toxicaria 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2013, 卷号: 76, 期号: 9, 页码: 1771-1780
作者:  Liu, Qian;  Tang, Jin-Shan;  Hu, Meng-Jie;  Liu, Jie;  Chen, Hai-Feng;  Gao, Hao;  Wang, Guang-Hui;  Li, Shun-Lin;  Hao, Xiao-Jiang;  Zhang, Xiao-Kun;  Yao, Xin-Sheng
浏览  |  Adobe PDF(2429Kb)  |  收藏  |  浏览/下载：222/95  |  提交时间：2015/05/13
Cheliensisin A Inhibits EGF-Induced Cell Transformation with Stabilization of p53 Protein Via a Hydrogen Peroxide/Chk1-Dependent Axis 期刊论文
CANCER PREVENTION RESEARCH, 2013, 卷号: 6, 期号: 9, 页码: 949-958
作者:  Zhang, Jingjie;  Gao, Guangxun;  Chen, Liang;  Deng, Xu;  Li, Jingxia;  Yu, Yonghui;  Zhang, Dongyun;  Li, Fei;  Zhang, Min;  Zhao, Qinshi;  Huang, Chuanshu
浏览  |  Adobe PDF(1677Kb)  |  收藏  |  浏览/下载：2728/241  |  提交时间：2013/10/16
Dna-damage  Cancer Chemoprevention  Induced Phosphorylation  Activation  Apoptosis  Expression  Induction  Hyperoxia  Therapy  Roles  
Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction 期刊论文
NATURE CHEMICAL BIOLOGY, 2013, 卷号: 9, 期号: 9, 页码: 579-U82
作者:  Wang, Sheng;  Yin, Junlin;  Chen, Duozhi;  Nie, Fen;  Song, Xiaomin;  Fei, Cong;  Miao, Haofei;  Jing, Changbin;  Ma, Wenjing;  Wang, Lei;  Xie, Sichun;  Li, Chen;  Zeng, Rong;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(1157Kb)  |  收藏  |  浏览/下载：638/131  |  提交时间：2013/10/16
Glycogen-synthase Kinase-3  Beta-catenin  Negative Regulator  Dix Domain  Stem-cells  In-vivo  Axin  Activation  Pathway  Phosphorylation  
Preventive and Therapeutic Effects of Adenanthin on Experimental Autoimmune Encephalomyelitis by Inhibiting NF-kappa B Signaling 期刊论文
JOURNAL OF IMMUNOLOGY, 2013, 卷号: 191, 期号: 5, 页码: 2115-2125
作者:  Yin, Qian-Qian;  Liu, Chuan-Xu;  Wu, Ying-Li;  Wu, Shao-Fang;  Wang, Yan;  Zhang, Xia;  Hu, Xiao-Juan;  Pu, Jian-Xin;  Lu, Ying;  Zhou, Hu-Chen;  Wang, Hong-Lin;  Nie, Hong;  Sun, Han-Dong;  Chen, Guo-Qiang
浏览  |  Adobe PDF(2420Kb)  |  收藏  |  浏览/下载：359/49  |  提交时间：2013/10/16
Autoreactive T-cells  Multiple-sclerosis  Rheumatoid-arthritis  Glatiramer Acetate  Activation  Inflammation  System  Roles  Mice  Differentiation  
Trichothecin Induces Cell Death in NF-kappa B Constitutively Activated Human Cancer Cells via Inhibition of IKK beta Phosphorylation 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 8, 页码: e71333
作者:  Su, Jia;  Zhao, Peiji;  Kong, Lingmei;  Li, Xingyao;  Yan, Juming;  Zeng, Ying;  Li, Yan
Adobe PDF(1124Kb)  |  收藏  |  浏览/下载：330/65  |  提交时间：2013/11/12
Colitis-associated Cancer  Multiple-myeloma Cells  P65 Phosphorylation  Endophytic Fungus  Kinase-activity  Tumor-growth  In-vitro  Pathway  Apoptosis  Inflammation