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New Phenolic Dimers from Plant Paeonia suffruticosa and Their Cytotoxicity and NO Production Inhibition 期刊论文
Molecules, 2023
作者:  Qianqian Meng;  Shunyao Tong;  Yuqing Zhao;  Xingrong Peng;  Zhenghui Li;  Tao Feng;  Jikai Liu
浏览  |  Adobe PDF(1414Kb)  |  收藏  |  浏览/下载：453/63  |  提交时间：2023/10/07
High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
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Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
作者:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
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Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Structurally Diverse Cytotoxic Polyphenols from Garcinia gracilis 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2023, 卷号: 86, 期号: 9, 页码: 2206-2215
作者:  Ye,Yan-Song;  Duan,Yao-Tao;  Zhou,Zhuo;  Thepkaysone,Khamphanh;  Douangdeuane,Bounleuane;  Xu,Gang
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CAGED XANTHONES  CONSTITUENTS  INHIBITORS  BENZOPHENONES  DERIVATIVES  BIPHENYL  TWIGS  
Chemical Constituents of Primulina eburnea (Gesneriaceae) and Their Cytotoxic Activities 期刊论文
CHEMISTRY & BIODIVERSITY, 2023
作者:  Yang,Li-Yuan;  Yi,Ping;  Chen,Jun-Lei;  Li,Yu-Huan;  Qiu,Jue-Lin;  Wang,Zhao-Yang;  Fu,Mao;  Yuan,Chun-Mao;  Huang,Lie-Jun;  Hao,Xiao-Jiang;  Gu,Wei
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Primulina eburnea  triterpenes  flavonoids  phenylethanoid glycosides  cytotoxic activity  GLUCOSIDES  LEAVES  CELL  
Guaiane-type Sesquiterpenoid Dimers from Artemisia zhongdianensis and Antihepatoma Carcinoma Activity via the p38MAPK Pathway 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2023, 卷号: 41, 期号: 19, 页码: 2453-2468
作者:  Dong,Wei;  Ma,Wen-Jing;  Ma,Yun-Bao;  Li,Feng-Jiao;  Li,Tian-Ze;  Wang,Yong-Cui;  He,Xiao-Feng;  Geng,Chang-An;  Zhang,Xue-Mei;  Chen,Ji-Jun
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Artemzhongdianolides B1-B17  Artemisia zhongdianensis  Guaiane-type sesquiterpenoid dimers  Antihepatoma activity  p38MAPK pathway  Cancer  NMR spectroscopy  X-ray diffraction  ARREST  CELLS  JNK  
Design and synthesis of guaianolide-germacranolide heterodimers as novel anticancer agents against hepatocellular carcinoma 期刊论文
DRUG DEVELOPMENT RESEARCH, 2023
作者:  Yan,Jia-Xin;  Li,Qi-Hao;  Li,Tian-Ze;  Huang,Zhi-Yan;  Ma,Yun-Bao;  Chen,Ji-Jun
Adobe PDF(7663Kb)  |  收藏  |  浏览/下载：3/1  |  提交时间：2024/07/10
antihepatoma effects  guaianolide-germacranolide heterodimers  PDGFRA  DERIVATIVES  
UPLC-Q-Orbitrap-MS/MS-Guided Isolation of Bioactive Withanolides from the Fruits of Physalis angulata 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 44, 页码: 16581-16592
作者:  Wang,Peng;  Yang,Xiao-Meng;  Hu,Zhan-Xing;  Li,Ya-Nan;  Yang,Jue;  Hao,Xiao-Jiang;  Yuan,Chun-Mao;  Yi,Ping
Adobe PDF(3336Kb)  |  收藏  |  浏览/下载：4/2  |  提交时间：2024/07/10
Physalis angulata  rare withanolidederivatives  isolation and identification  anticancer  anti-inflammatory activity  CYTOTOXIC WITHANOLIDES  CONSTITUENTS  PLANTS  L.  
Artemdubinoids A-N: novel sesquiterpenoids with antihepatoma cytotoxicity from Artemisia dubia 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2023, 卷号: 21, 期号: 12, 页码: 902-915
作者:  Gao,Zhen;  Li,Tianze;  Ma,Yunbao;  Huang,Xiaoyan;  Geng,Changan;  Zhang,Xuemei;  Chen,Jijun
Adobe PDF(872Kb)  |  收藏  |  浏览/下载：2/2  |  提交时间：2024/07/22
Artemdubinoids A-N  Artemisia dubia  Sesquiterpenoids  Antihepatoma activity  
Development of actein derivatives as potent anti-triple negative breast cancer agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 89, 页码: 129307
作者:  Zhang,Honglin;  Chen,Yiyan;  Huang,Songwen;  Xiao,Wen-Wen;  Qiu,Ming-Hua;  Shao,Li-Dong;  Chen,Chuan-Huizi;  Li,Dashan
Adobe PDF(1187Kb)  |  收藏  |  浏览/下载：5/2  |  提交时间：2024/07/22
Actein  Modification  Triple negative breast cancer  Structure-activity relationships  Mechanism  GROWTH-INHIBITORY ACTIVITY  BLACK COHOSH  EXTRACTS