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Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(9057Kb)  |  收藏  |  浏览/下载：228/46  |  提交时间：2020/03/26
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
作者:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(1740Kb)  |  收藏  |  浏览/下载：231/31  |  提交时间：2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Zhu, Xu;  Xiao, Xue-Rong;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(3136Kb)  |  收藏  |  浏览/下载：188/61  |  提交时间：2019/09/10
elemicin  l'-hydroxyelemicin  metabolic activation  cytotoxicity  
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(1101Kb)  |  收藏  |  浏览/下载：272/112  |  提交时间：2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
The sources and mechanisms of bioactive ingredients in coffee 期刊论文
FOOD & FUNCTION, 2019, 卷号: 10, 期号: 6, 页码: 3113-3126
作者:  Hu, G. L.;  Wang, X.;  Zhang, L.;  Qiu, M. H.
浏览  |  Adobe PDF(2231Kb)  |  收藏  |  浏览/下载：211/58  |  提交时间：2019/09/10
Metabolic Activation of Myristicin and Its Role in Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 15, 页码: 4328-4336
作者:  Zhu, Xu;  Wang, Yi-Kun;  Yang, Xiao-Nan;  Xiao, Xue-Rong;  Zhang, Ting;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Li, Fei
浏览  |  Adobe PDF(4316Kb)  |  收藏  |  浏览/下载：239/44  |  提交时间：2019/05/24
myristicin  1 '-hydroxymyristicin  metabolic activation  metabolomics  
Statistically correlating NMR spectra and LC-MS data to facilitate the identification of individual metabolites in metabolomics mixtures 期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2019, 卷号: 411, 期号: 7, 页码: 1301-1309
作者:  Li, Xing;  Luo, Huan;  Huang, Tao;  Xu, Li;  Shi, Xiaohuo;  Hu, Kaifeng
浏览  |  Adobe PDF(1588Kb)  |  收藏  |  浏览/下载：204/49  |  提交时间：2019/07/29
Deconvolution  LC-MS  NMR  Statistical correlation  Structure identification  
Quantitative proteomics analysis of Caenorhabditis elegans upon germ cell loss 期刊论文
JOURNAL OF PROTEOMICS, 2017, 卷号: 156, 期号: 1, 页码: 85-93
作者:  Pu, Yuan-Zhu;  Wan, Qin-Li;  Ding, Ai-Jun;  Luo, Huai-Rong;  Wu, Gui-Sheng
浏览  |  Adobe PDF(1197Kb)  |  收藏  |  浏览/下载：322/107  |  提交时间：2017/05/19
Caenorhabditis Elegans  Proteomics  Aging  Notch Receptor Glp-1  Reproduction  
The Natural Diterpenoid Isoforretin A Inhibits Thioredoxin-1 and Triggers Potent ROS-Mediated Antitumor Effects 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 4, 页码: 926-936
作者:  Sun, Xiaoyan;  Wang, Weiguang;  Chen, Jiao;  Cai, Xueting;  Yang, Jie;  Yang, Yang;  Yan, Huaijiang;  Cheng, Xiaolan;  Ye, Juan;  Lu, Wuguang;  Hu, Chunping;  Sun, Handong;  Pu, Jianxin;  Cao, Peng
浏览  |  Adobe PDF(1370Kb)  |  收藏  |  浏览/下载：471/219  |  提交时间：2017/02/28
Metabolomic signature associated with reproduction-regulated aging in Caenorhabditis elegans 期刊论文
AGING-US, 2017, 卷号: 9, 期号: 2, 页码: 447-474
作者:  Wan, Qin-Li;  Shi, Xiaohuo;  Liu, Jiangxin;  Ding, Ai-Jun;  Pu, Yuan-Zhu;  Li, Zhigang;  Wu, Gui-Sheng;  Luo, Huai-Rong
浏览  |  Adobe PDF(4040Kb)  |  收藏  |  浏览/下载：194/55  |  提交时间：2017/05/19
Caenorhabditis Elegans  Aging  Reproduction  Metabolome  Uplc-ms And Nmr