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Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 775-787
作者:  Liu, Chin-Yu;  Cheng, Yung-Yi;  Chang, Ling-Chu;  Huang, Li-Jiau;  Chou, Li-Chen;  Huang, Chi-Hung;  Tsai, Meng-Tung;  Liao, Chih-Chang;  Hsu, Mei-Hua;  Lin, Hui-Yi;  Wu, Tian-Shung;  Wen, Yen-Fang;  Zhao, Yu;  Kuo, Sheng-Chu;  Lee, Kuo-Hsiung;  Kuo,SC (reprint author),China Med Univ,Grad Inst Pharmaceut Chem,91 Hsueh Shih Rd,Taichung 40402,Taiwan.;  sckuo@mail.cmu.edu.tw;  khlee@unc.edu
浏览  |  Adobe PDF(1696Kb)  |  收藏  |  浏览/下载：334/75  |  提交时间：2015/06/29
2-arylnaphthyridin-4-ones  Antitumor Agents  Phosphate Prodrug  
Multidrug resistance-selective antiproliferative activity of Piper amide alkaloids and synthetic analogues 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 20, 页码: 4818-4821
作者:  Wang, Yue-Hu;  Goto, Masuo;  Wang, Li-Ting;  Hsieh, Kan-Yen;  Morris-Natschke, Susan L.;  Tang, Gui-Hua;  Long, Chun-Lin;  Lee, Kuo-Hsiung;  Wang,YH (reprint author),Univ N Carolina,Eshelman Sch Pharm,Nat Prod Res Labs,Chapel Hill,NC 27599 USA.;  wangyuehu@mail.kib.ac.cn;  khlee@unc.edu
Adobe PDF(492Kb)  |  收藏  |  浏览/下载：296/69  |  提交时间：2014/11/25
Piper  Piperaceae  Amide Alkaloids  Cytotoxicity  Multidrug Resistance  
Diarylheptanoids and phenylphenalenones from Musa itinerans fruits 期刊论文
PHYTOCHEMISTRY, 2014, 卷号: 103, 期号: 1, 页码: 171-177
作者:  Liu, Fang;  Zhang, Yu;  Sun, Qian-Yun;  Yang, Fu-Mei;  Gu, Wei;  Yang, Jun;  Niu, Hong-Mei;  Wang, Yue-Hu;  Long, Chun-Lin;  Wang,YH (reprint author),Chinese Acad Sci,Kunming Inst Bot,Kunming 650201,Peoples R China.;  wangyuehu@mail.kib.ac.cn;  long@mail.kib.ac.cn
Adobe PDF(629Kb)  |  收藏  |  浏览/下载：316/76  |  提交时间：2014/07/28
Musaceae  Musa Itinerans  Diarylheptanoids  Phenylphenalenones  Cytotoxicity  
Antiproliferative Cardiac Glycosides from the Latex of Antiaris toxicaria 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2013, 卷号: 76, 期号: 9, 页码: 1771-1780
作者:  Liu, Qian;  Tang, Jin-Shan;  Hu, Meng-Jie;  Liu, Jie;  Chen, Hai-Feng;  Gao, Hao;  Wang, Guang-Hui;  Li, Shun-Lin;  Hao, Xiao-Jiang;  Zhang, Xiao-Kun;  Yao, Xin-Sheng
浏览  |  Adobe PDF(2429Kb)  |  收藏  |  浏览/下载：206/92  |  提交时间：2015/05/13
Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-kappa B Activation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 11, 页码: 4749-4757
作者:  Zhao, Yu;  Su, Jia;  Goto, Masuo;  Morris-Natschke, Susan L.;  Li, Yan;  Zhao, Qin-Shi;  Yao, Zhu-Jun;  Lee, Kuo-Hsiung
浏览  |  Adobe PDF(531Kb)  |  收藏  |  浏览/下载：311/65  |  提交时间：2013/10/16
Natural-products  Biological-activity  Cancer-therapy  Paclitaxel  Taxol  Resistance  Drugs  Chemotherapy  Parthenolide  Brevifoliol  
Evaluation of anti-HCV activity and SAR study of (+)-lycoricidine through targeting of host heat-stress cognate 70 (Hsc70) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 9, 页码: 2679-2682
作者:  Chen, Duo-Zhi;  Jiang, Jian-Dong;  Zhang, Ke-Qing;  He, Hong-Ping;  Di, Ying-Tong;  Zhang, Yu;  Cai, Jie-Yun;  Wang, Lei;  Li, Shun-Lin;  Yi, Ping;  Peng, Zong-Gen;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(555Kb)  |  收藏  |  浏览/下载：510/105  |  提交时间：2013/06/08
(+)-lycoricidine  Heat-stress Cognate 70 (Hsc70)  Down-regulators  Structure-activity Relationship (Sar)  Anti-hcv Activity  
ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2012, 卷号: 30, 期号: 6, 页码: 1226-1230
作者:  Wang Weiguang;  Wu Haiyan;  Du Xue;  Yan Juming;  Li Yan;  Pu Jianxin;  Sun Handong
Adobe PDF(535Kb)  |  收藏  |  浏览/下载：231/73  |  提交时间：2014/04/02
Ent-kaurane Diterpenoid  Isodon  Structure Elucidation  Cytotoxicity  
Cycloartane triterpenoids from the aerial parts of Cimicifuga foetida Linnaeus 期刊论文
PHYTOCHEMISTRY, 2011, 卷号: 72, 期号: 11-12, 页码: 1473-1481
作者:  Nian, Yin;  Zhang, Xian-Min;  Li, Yan;  Wang, Yuan-Yuan;  Chen, Jian-Chao;  Lu, Lu;  Zhou, Lin;  Qiu, Ming-Hua
Adobe PDF(368Kb)  |  收藏  |  浏览/下载：537/169  |  提交时间：2012/04/10
Cimicifuga Foetida  Ranunculaceae  Cycloartane Triterpenoids  Cytotoxicity  Structure-activity Relationships  
Isoprenylated cyclohexanoids from the basidiomycete Hexagonia speciosa 期刊论文
PHYTOCHEMISTRY, 2011, 卷号: 72, 期号: 9, 页码: 923-928
作者:  Jiang, Meng-Yuan;  Li, Yan;  Wang, Fei;  Liu, Ji-Kai
Adobe PDF(231Kb)  |  收藏  |  浏览/下载：333/103  |  提交时间：2012/04/10
Hexagonia Speciosa  Basidiomycete  Cyclohexanoids  Speciosins L-t  
Abietane Diterpenoids and a Lignan from Pinus yunnanensis 期刊论文
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2010, 卷号: 65, 期号: 6, 页码: 765-769
作者:  Feng, Tao;  Cai, Xiang-Hai;  Tan, Qin-Gang;  Luo, Xiao-Dong
Adobe PDF(123Kb)  |  收藏  |  浏览/下载：310/102  |  提交时间：2012/07/25
Pinus Yunnanensis  Pinaceae  Diterpenoids  Lignan  Anti-inflammatory Activity  Cytotoxicity