ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora

doi:10.1002/cjoc.201100653

	ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora
	Wang Weiguang 1,2; Wu Haiyan 1; Du Xue 1; Yan Juming 1; Li Yan1 ; Pu Jianxin1 ; Sun Handong1
通讯作者	Pu, JX (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kuming 650201, Yunan, Peoples R China,pujianxin@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn
	2012-06-01
发表期刊	CHINESE JOURNAL OF CHEMISTRY
ISSN	1001-604X
卷号	30 期号:6 页码:1226-1230
摘要	Four new ent-kaurane diterpenoids, 6 beta,13a,15 beta-trihydroxy-16-ene-3a,20-epoxy-ent-kaur-1,7-dione (1), 6-hydroxy-3a,20-epoxy-5(6)-ene-ent-kaur-1,7,15-trione (2), 6-hydroxy-15 beta-acetoxy-3a,20-epoxy-16 beta,17-epoxy-5(6)-ene-ent-kaur-1,7-dione (3), 3a,17-dihydroxy-15(16)-ene-ent-kaur-7-one (4), along with four known compounds 58 were isolated from the leaves of Isodon eriocalyx var. laxiflora. The structures were elucidated by extensive spectroscopic methods (IR, UV, MS and NMR). The cytotoxic activities of these compounds were evaluated by MTT assay. Compound 8 showed moderate inhibitory effects on HL-60, SMMC-7721, MCF-7 and SW-480 cell lines.
关键词	Ent-kaurane Diterpenoid Isodon Structure Elucidation Cytotoxicity
学科领域	Chemistry
DOI	10.1002/cjoc.201100653
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000305389200005
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/17608
专题	植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Yunan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Kunming 650201, Yunan, Peoples R China
推荐引用方式 GB/T 7714	Wang Weiguang,Wu Haiyan,Du Xue,et al. ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora[J]. CHINESE JOURNAL OF CHEMISTRY,2012,30(6):1226-1230.
APA	Wang Weiguang.,Wu Haiyan.,Du Xue.,Yan Juming.,Li Yan.,...&Sun Handong.(2012).ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora.CHINESE JOURNAL OF CHEMISTRY,30(6),1226-1230.
MLA	Wang Weiguang,et al."ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora".CHINESE JOURNAL OF CHEMISTRY 30.6(2012):1226-1230.

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