ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora
Wang Weiguang1,2; Wu Haiyan1; Du Xue1; Yan Juming1; Li Yan1; Pu Jianxin1; Sun Handong1
Corresponding AuthorPu, JX (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kuming 650201, Yunan, Peoples R China,pujianxin@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn
2012-06-01
Source PublicationCHINESE JOURNAL OF CHEMISTRY
ISSN1001-604X
Volume30Issue:6Pages:1226-1230
AbstractFour new ent-kaurane diterpenoids, 6 beta,13a,15 beta-trihydroxy-16-ene-3a,20-epoxy-ent-kaur-1,7-dione (1), 6-hydroxy-3a,20-epoxy-5(6)-ene-ent-kaur-1,7,15-trione (2), 6-hydroxy-15 beta-acetoxy-3a,20-epoxy-16 beta,17-epoxy-5(6)-ene-ent-kaur-1,7-dione (3), 3a,17-dihydroxy-15(16)-ene-ent-kaur-7-one (4), along with four known compounds 58 were isolated from the leaves of Isodon eriocalyx var. laxiflora. The structures were elucidated by extensive spectroscopic methods (IR, UV, MS and NMR). The cytotoxic activities of these compounds were evaluated by MTT assay. Compound 8 showed moderate inhibitory effects on HL-60, SMMC-7721, MCF-7 and SW-480 cell lines.
KeywordEnt-kaurane Diterpenoid Isodon Structure Elucidation Cytotoxicity
Subject AreaChemistry
DOI10.1002/cjoc.201100653
Indexed BySCI ; IC
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000305389200005
Citation statistics
Cited Times:6[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/17608
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Yunan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Kunming 650201, Yunan, Peoples R China
Recommended Citation
GB/T 7714
Wang Weiguang,Wu Haiyan,Du Xue,et al. ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora[J]. CHINESE JOURNAL OF CHEMISTRY,2012,30(6):1226-1230.
APA Wang Weiguang.,Wu Haiyan.,Du Xue.,Yan Juming.,Li Yan.,...&Sun Handong.(2012).ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora.CHINESE JOURNAL OF CHEMISTRY,30(6),1226-1230.
MLA Wang Weiguang,et al."ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora".CHINESE JOURNAL OF CHEMISTRY 30.6(2012):1226-1230.
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