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题名: ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora
作者: Wang Weiguang1, 2; Wu Haiyan1; Du Xue1; Yan Juming1; null(李艳)1; Pu Jianxin1; null(孙汉董)1
刊名: CHINESE JOURNAL OF CHEMISTRY
关键词: ent-Kaurane diterpenoid ; Isodon ; structure elucidation ; cytotoxicity
英文摘要: Four new ent-kaurane diterpenoids, 6 beta,13a,15 beta-trihydroxy-16-ene-3a,20-epoxy-ent-kaur-1,7-dione (1), 6-hydroxy-3a,20-epoxy-5(6)-ene-ent-kaur-1,7,15-trione (2), 6-hydroxy-15 beta-acetoxy-3a,20-epoxy-16 beta,17-epoxy-5(6)-ene-ent-kaur-1,7-dione (3), 3a,17-dihydroxy-15(16)-ene-ent-kaur-7-one (4), along with four known compounds 58 were isolated from the leaves of Isodon eriocalyx var. laxiflora. The structures were elucidated by extensive spectroscopic methods (IR, UV, MS and NMR). The cytotoxic activities of these compounds were evaluated by MTT assay. Compound 8 showed moderate inhibitory effects on HL-60, SMMC-7721, MCF-7 and SW-480 cell lines.
出版日期: 2012-06-01
卷号: 30, 期号:6, 页码:1226-1230
DOI标识: 10.1002/cjoc.201100653
语种: 英语
ISSN号: 1001-604X
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/17608
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650201, Yunan, Peoples R China
2.Chinese Acad Sci, Grad Sch, Kunming 650201, Yunan, Peoples R China

Recommended Citation:
Wang Weiguang;Wu Haiyan;Du Xue;Yan Juming;Li Yan;Pu Jianxin;Sun Handong.ent-Kaurane Diterpenoids from Isodon eriocalyx var. laxiflora,CHINESE JOURNAL OF CHEMISTRY,2012,30(6):1226-1230
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