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RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 9, 页码: 14
作者:  Guo, Di;  Wang, Yurong;  Wang, Jing;  Song, Lihua;  Wang, Zhe;  Mao, Bingyu;  Tan, Ninghua
浏览  |  Adobe PDF(9639Kb)  |  收藏  |  浏览/下载：133/23  |  提交时间：2019/07/29
RA-XII  lipogenesis  SCAP  SREBP  liver cancer  
Redox Dual-Responsive and O-2-Evolving Theranostic Nanosystem for Highly Selective Chemotherapy against Hypoxic Tumors 期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 1, 页码: 90-103
作者:  Chen, Huachao;  Li, Fei;  Yao, Yongrong;  Wang, Zhe;  Zhang, Zhihao;  Tan, Ninghua
浏览  |  Adobe PDF(3409Kb)  |  收藏  |  浏览/下载：175/45  |  提交时间：2019/07/29
cancer  theranostic system  hypoxic tumor  ROS/GSH dual-activatable  cyclopeptide RA-V  fluorescence imaging  
(+/-)-Rubioncolin D, a pair of enantiomeric naphthohydroquinone dimers from Rubia oncotricha 期刊论文
TETRAHEDRON LETTERS, 2017, 卷号: 58, 期号: 31, 页码: 3041-3043
作者:  Zhao, Si-Meng;  Wang, Zhe;  Chen, Xiao-Qiang;  Huang, Mao-Bo;  Tan, Ning-Hua
Adobe PDF(926Kb)  |  收藏  |  浏览/下载：169/42  |  提交时间：2017/10/23
Rubio Oncotricha  Naphthohydroquinone Dimers  Rubioncolin d  
Rubicordins A-C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-kappa B signaling pathway 期刊论文
TETRAHEDRON, 2015, 卷号: 71, 期号: 52, 页码: 9673-9678
作者:  Chen, Xiao-Qiang;  Zhao, Si-Meng;  Wang, Zhe;  Zeng, Guang-Zhi;  Huang, Mao-Bo;  Tan, Ning-Hua
Adobe PDF(1412Kb)  |  收藏  |  浏览/下载：675/139  |  提交时间：2016/02/01
Rubia Cordifolia  Rubicordins A-c  Cyclopeptides  Cytotoxicity  Nf-kappa b Signaling Pathway  
Rubipodanin A, the First Natural N-Desmonomethyl Rubiaceae-Type Cyclopeptide from Rubia podantha, Indicating an Important Role of the N-9-Methyl Group in the Conformation and Bioactivity 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 12
作者:  Wang, Zhe;  Zhao, Si-Meng;  Zhao, Li-Mei;  Chen, Xiao-Qiang;  Zeng, Guang-Zhi;  Tan, Ning-Hua
Adobe PDF(805Kb)  |  收藏  |  浏览/下载：692/181  |  提交时间：2016/02/01
Cyclopeptide RA-V inhibits cell adhesion and invasion in both estrogen receptor positive and negative breast cancer cells via PI3K/AKT and NF-kappa B signaling pathways 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2015, 卷号: 1853, 期号: 8, 页码: 1827-1840
作者:  Leung, Hoi-Wing;  Wang, Zhe;  Yue, Grace Gar-Lee;  Zhao, Si-Meng;  Lee, Julia Kin-Ming;  Fung, Kwok-Pui;  Leung, Ping-Chung;  Lau, Clara Bik-San;  Tan, Ning-Hua;  Lau,CBS (reprint author),Chinese Univ Hong Kong,Inst Chinese Med,Shatin,Hong Kong,Peoples R China.;  claralau@cuhk.edu.hk;  nhtan@mail.kib.ac.cn
浏览  |  Adobe PDF(2434Kb)  |  收藏  |  浏览/下载：281/45  |  提交时间：2015/07/20
Cyclopeptide  Cell Adhesion  Cell Invasion  Metastasis  Breast Cancer  
Cyclopentapeptides from Dianthus chinensis 期刊论文
JOURNAL OF PEPTIDE SCIENCE, 2015, 卷号: 21, 期号: 7, 页码: 550-553
作者:  Han, Jing;  Huang, Maobo;  Wang, Zhe;  Zheng, Yuqing;  Zeng, Guangzhi;  He, Wenjun;  Tan, Ninghua
浏览  |  Adobe PDF(259Kb)  |  收藏  |  浏览/下载：168/66  |  提交时间：2015/12/15
Cyclopentapeptides  Caryophyllaceae  Dianthus Chinensis  Dianthin i  
New Cytotoxic Naphthohydroquinone Dimers from Rubia alata 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 21, 页码: 5576-5579
作者:  Zhao, Si-Meng;  Wang, Zhe;  Zeng, Guang-Zhi;  Song, Wei-Wu;  Chen, Xiao-Qiang;  Li, Xiao-Nian;  Tan, Ning-Hua;  Zeng,GZ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  gzh_zeng@mail.kib.ac.cn;  nhtan@mail.kib.ac.cn
浏览  |  Adobe PDF(253Kb)  |  收藏  |  浏览/下载：221/47  |  提交时间：2015/01/20
Chiral Bicyclic Lactams  1st Total-synthesis  Asymmetric-synthesis  Helquist Annulation  Magellanine-type  L-paniculatum  (-)-8-deoxyserratinine