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Labdane and isopimarane diterpenoids from Rosmarinus officinalis solid wastes: MS/MS spectrometric fragmentations and neuroprotective effect 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2022, 卷号: 177, 页码: 114441
作者:  Chen,Xinglong;  Luo,Qingyi;  Hu,Weiyan;  Chen,Jijun;  Zhang,Rongping
收藏  |  浏览/下载：61/0  |  提交时间：2022/04/02
Rosmarinus officinalis  Solid wastes  Labdane diterpenoids  Isopimarane diterpenoids  MS/MS fragmentations  Neuroprotective effect  CARNOSIC ACID  ANTIOXIDANT ACTIVITY  BIOSYNTHESIS  
Artematrovirenolides A-D and Artematrolides S-Z, Sesquiterpenoid Dimers with Cytotoxicity against Three Hepatoma Cell Lines from Artemisia atrovirens 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2022, 卷号: 40, 期号: 1, 页码: 104-114
作者:  Su,Li-Hua;  Li,Tian-Ze;  Ma,Yun-Bao;  Geng,Chang-An;  Huang,Xiao-Yan;  Zhang,Xin;  Gao,Zhen;  Chen,Ji-Jun
浏览  |  Adobe PDF(2103Kb)  |  收藏  |  浏览/下载：131/50  |  提交时间：2022/04/02
Artemisia atrovirens  Sesquiterpenoid dimers  Structure elucidation  X-ray diffraction  Antihepatoma activity  GUAIANOLIDE  ARGYI  
Design and synthesis of ludartin derivatives as potential anticancer agents against hepatocellular carcinoma 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 7, 页码: 1224-1239
作者:  Sun, Jin-Jin;  Wang, Jin-Ping;  Li, Tian-Ze;  Ma, Yun-Bao;  Xue, Dong;  Chen, Ji-Jun
Adobe PDF(1092Kb)  |  收藏  |  浏览/下载：1/0  |  提交时间：2024/04/30
Ludartin derivatives  Antihepatoma activity  HepG2 cells  Huh7 cells  SESQUITERPENE LACTONES  CHEMICAL-CONSTITUENTS  GUAIANOLIDES  ANTITUMOR  ANALOGS  
Synthesis and biological evaluation of (+)-paeoveitol derivatives as novel antidepressants 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 11, 页码: 2045-2057
作者:  Li, Tian-Ze;  Huang, Xiao-Yan;  Sun, Jin-Jin;  Geng, Chang-An;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(1234Kb)  |  收藏  |  浏览/下载：6/1  |  提交时间：2024/04/30
(+)-Paeoveitol derivatives  Antidepressant  Forced swimming test  Monoamine neurotransmitter  
Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol derivatives as alpha-glucosidase and PTP1B inhibitors 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 2, 页码: 350-367
作者:  Yang, Xiao-Tong;  Li, Tian-Ze;  Geng, Chang-An;  Liu, Pei;  Chen, Ji-Jun
Adobe PDF(1348Kb)  |  收藏  |  浏览/下载：4/0  |  提交时间：2024/04/30
(20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol  alpha-glucosidase inhibitors  PTP1B inhibitors  Enzyme kinetics  TYROSINE-PHOSPHATASE 1B  DIABETES-MELLITUS  EPIDEMIOLOGY  
Synthesis and biological evaluation of paeoveitol D derivatives as new melatonin receptor agonists with antidepressant activities 期刊论文
RSC MEDICINAL CHEMISTRY, 2022, 卷号: 13, 期号: 10, 页码: 1212-1224
作者:  Li, Tian-Ze;  Hu, Jing;  Sun, Jin-Jin;  Huang, Xiao-Yan;  Geng, Chang-An;  Liu, Shu-Bai;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(932Kb)  |  收藏  |  浏览/下载：6/1  |  提交时间：2024/04/30
BENZOFURAN  
Phylogenetic patterns suggest frequent multiple origins of secondary metabolites across the seed-plant 'tree of life' 期刊论文
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8, 期号: 4, 页码: nwaa105
作者:  Zhang,Yongzeng;  Deng,Tao;  Sun,Lu;  Landis,Jacob B.;  Moore,Michael J.;  Wang,Hengchang;  Wang,Yuehua;  Hao,Xiaojiang;  Chen,Jijun;  Li,Shenghong;  Xu,Maonian;  Puno,Pema-Tenzin;  Raven,Peter H.;  Sun,Hang
收藏  |  浏览/下载：99/0  |  提交时间：2022/04/02
secondary metabolites  phylogenetic tree  phylogenetic signal  co-diversification  evolution  bioprospecting  seed plants  DIVERSIFICATION  EVOLUTION  DIVERSITY  SIGNAL  ANGIOSPERMS  CHEMISTRY  DEFENSES  FOSSIL  KEYS  
New guaiane-type sesquiterpenoid dimers from Artemisia atrovirens and their antihepatoma activity 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 6, 页码: 1648-1666
作者:  Su,Lihua;  Zhang,Xintian;  Ma,Yunbao;  Geng,Changan;  Huang,Xiaoyan;  Hu,Jing;  Li,Tianze;  Tang,Shuang;  Shen,Cheng;  Gao,Zhen;  Zhang,Xuemei;  Chen,Ji-Jun
Adobe PDF(4074Kb)  |  收藏  |  浏览/下载：86/32  |  提交时间：2022/04/02
Guaianolide dimers  Artematrolides AeR  Artemisia atrovirens  Cytotoxicity  Cell cycle  Apoptosis  FARNESYL-PROTEIN TRANSFERASE  CELL-CYCLE ARREST  HEPATOCELLULAR-CARCINOMA  GUAIANOLIDES  LACTONES  INHIBITORS  ARTEMINOLIDE  APOPTOSIS  ARGYI  HELA  
Artematrovirenins A-P, guaiane-type sesquiterpenoids with cytotoxicities against two hepatoma cell lines from Artemisia atrovirens 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105072
作者:  Su,Li-Hua;  Ma,Yun-Bao;  Geng,Chang-An;  Li,Tian-Ze;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xin;  Tang,Shuang;  Shen,Cheng;  Gao,Zhen;  Zhang,Xue-Mei;  Chen,Ji-Jun
浏览  |  Adobe PDF(2611Kb)  |  收藏  |  浏览/下载：127/68  |  提交时间：2022/04/02
Artemisia atrovirens  guaiane-type sesquiterpenoids  artematrovirenins A-P  HepG2 and Huh7 cell lines  antihepatic cytotoxicity  LACTONES  CONSTITUENTS  GUAIANOLIDES  
Artematrolide A inhibited cervical cancer cell proliferation via ROS/ERK/mTOR pathway and metabolic shift 期刊论文
PHYTOMEDICINE, 2021, 卷号: 91, 页码: 153707
作者:  Zhang,Xin-Tian;  Hu,Jing;  Su,Li-Hua;  Geng,Chang-An;  Chen,Ji-Jun
浏览  |  Adobe PDF(6313Kb)  |  收藏  |  浏览/下载：69/26  |  提交时间：2022/04/02
Artemisia atrovirens  Cervical cancer  ERK pathway  Cell metabolism  ALKALINE-PHOSPHATASE  SIGNALING PATHWAY  DIFFERENTIATION  APOPTOSIS  ERK  MECHANISMS