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Functional Genome Mining Reveals a Class V Lanthipeptide Containing ad-Amino Acid Introduced by an F420H2-Dependent Reductase 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020
作者:  Xu, Min;  Zhang, Fei;  Cheng, Zhuo;  Bashiri, Ghader;  Wang, Jing;  Hong, Jiali;  Wang, Yemin;  Xu, Lijun;  Chen, Xuefei;  Huang, Sheng-Xiong;  Lin, Shuangjun;  Deng, Zixin;  Tao, Meifeng
浏览  |  Adobe PDF(1545Kb)  |  收藏  |  浏览/下载：134/33  |  提交时间：2021/01/05
Divergent biosynthesis of indole alkaloids FR900452 and spiro-maremycins 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2018, 卷号: 16, 期号: 30, 页码: 5446-5451
作者:  Duan, Yingyi;  Liu, Yanyan;  Huang, Tao;  Zou, Yi;  Huang, Tingting;  Hu, Kaifeng;  Deng, Zixin;  Lin, Shuangjun
收藏  |  浏览/下载：100/0  |  提交时间：2018/09/17
Metabolic Engineering-Based Rapid Characterization of a Sesquiterpene Cyclase and the Skeletons of Fusariumdiene and Fusagramineol from Fusarium graminearum 期刊论文
ORGANIC LETTERS, 2018, 卷号: 20, 期号: 6, 页码: 1626-1629
作者:  Bian, Guangkai;  Hou, Anwei;  Yuan, Yujie;  Hu, Ben;  Cheng, Shu;  Ye, Ziling;  Di, Yingtong;  Deng, Zixin;  Liu, Tiangang
浏览  |  Adobe PDF(1089Kb)  |  收藏  |  浏览/下载：158/49  |  提交时间：2018/05/08
Functional Genome Mining for Metabolites Encoded by Large Gene Clusters through Heterologous Expression of a Whole-Genome Bacterial Artificial Chromosome Library in Streptomyces spp. 期刊论文
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2016, 卷号: 82, 期号: 19, 页码: 5795-5805
作者:  Xu, Min;  Wang, Yemin;  Zhao, Zhilong;  Gao, Guixi;  Huang, Sheng-Xiong;  Kang, Qianjin;  He, Xinyi;  Lin, Shuangjun;  Pang, Xiuhua;  Deng, Zixin;  Tao, Meifeng
浏览  |  Adobe PDF(1798Kb)  |  收藏  |  浏览/下载：223/50  |  提交时间：2017/01/05
Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2015, 卷号: 172, 期号: 14, 页码: 3495-3509
作者:  Zhu, Yingmin;  Lu, Yungang;  Qu, Chunrong;  Miller, Melissa;  Tian, Jinbin;  Thakur, Dhananjay P.;  Zhu, Jinmei;  Deng, Zixin;  Hu, Xianming;  Wu, Meng;  McManus, Owen B.;  Li, Min;  Hong, Xuechuan;  Zhu, Michael X.;  Luo, Huai-Rong
浏览  |  Adobe PDF(2298Kb)  |  收藏  |  浏览/下载：183/45  |  提交时间：2015/12/15
Synthesis and neurotrophic activity evaluation of amaryllidaceae alkaloids 期刊论文
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 卷号: 246
作者:  Luo, Huairong;  He, Maomao;  Zhu, Jinmei;  Wu, Chunfeng;  Deng, Zixin;  Hong, Xuechuan
收藏  |  浏览/下载：223/0  |  提交时间：2015/05/14
Synthesis, biological evaluation and molecular modeling of substituted 2-aminobenzimidazoles as novel inhibitors of acetylcholinesterase and butyrylcholinesterase 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 14, 页码: 4218-4224
作者:  Zhu, Jinmei;  Wu, Chun-Feng;  Li, Xiaobing;  Wu, Gui-Sheng;  Xie, Shan;  Hu, Qian-Nan;  Deng, Zixin;  Zhu, Michael X.;  Luo, Huai-Rong;  Hong, Xuechuan
浏览  |  Adobe PDF(1174Kb)  |  收藏  |  浏览/下载：528/89  |  提交时间：2013/10/16
Alzheimer's Disease  Acetylcholinesterase  Butyrylcholinesterase  Molecular Modeling  2-aminobenzimidazole  
Dual Carbamoylations on the Polyketide and Glycosyl Moiety by Asm21 Result in Extended Ansamitocin Biosynthesis 期刊论文
CHEMISTRY & BIOLOGY, 2011, 卷号: 18, 期号: 12, 页码: 1571-1580
作者:  Li, Yan;  Zhao, Peiji;  Kang, Qianjin;  Ma, Juan;  Bai, Linquan;  Deng, Zixin
Adobe PDF(986Kb)  |  收藏  |  浏览/下载：350/98  |  提交时间：2012/07/25
Antitumor Agent Ansamitocin  Beta-lactam Antibiotics  Actinosynnema-pretiosum  Gene-cluster  Dna Gyrase  Concanamycin-a  Streptomyces  Novobiocin  Carbamoyltransferase  Inhibitors  
Metal-free direct amidation of peptidyl thiol esters with alpha-amino acid esters 期刊论文
GREEN CHEMISTRY, 2011, 卷号: 13, 期号: 10, 页码: 2723-2726
作者:  Chen, Hao;  He, Maomao;  Wang, Yaya;  Zhai, Linhui;  Cui, Yongbo;  Li, Yangyan;  Li, Yan;  Zhou, Haibing;  Hong, Xuechuan;  Deng, Zixin
Adobe PDF(182Kb)  |  收藏  |  浏览/下载：321/102  |  提交时间：2012/07/25
Native Chemical Ligation  Catalyzed Double Carbohydroamination  Amide Synthesis  Mild Amidation  One-pot  Oxidative Amidation  General-solution  Aldehydes  Alcohols  Efficient  
Amide N-glycosylation by Asm25, an N-glycosyltransferase of ansamitocins 期刊论文
CHEMISTRY & BIOLOGY, 2008, 卷号: 15, 期号: 8, 页码: 863-874
作者:  Zhao, Peiji;  Bai, Linquan;  Ma, Juan;  Zeng, Ying;  Li, Lei;  Zhang, Yirong;  Lu, Chunhua;  Dai, Huanqin;  Wu, Zhaoxian;  Li, Yaoyao;  Wu, Xuan;  Chen, Gang;  Hao, Xiaojiang;  Shen, Yuemao;  Deng, Zixin;  Floss, Heinz G.
Adobe PDF(1375Kb)  |  收藏  |  浏览/下载：343/125  |  提交时间：2011/11/24
Biosynthetic Gene-cluster  Lechevalieria-aerocolonigenes Atcc-39243  Escherichia-coli  3-amino-5-hydroxybenzoic Acid  Actinosynnema-pretiosum  Maytansinoid Antibiotics  Streptomyces Sp  Indolocarbazole  Expression  Substrate