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Synthesis and biological evaluation of novel 3-benzylcoumarin-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 4, 页码: 6
作者:  Wang, Xue-Quan;  Chen, Xue-Bing;  Ye, Ping-Ting;  Yang, Zhi-Xin;  Bai, Meng-Jiao;  Duan, Su-Yue;  Li, Yan;  Yang, Xiao-Dong
收藏  |  浏览/下载：235/0  |  提交时间：2020/03/18
3-Benzylcoumarin  Imidazolium salts  Biological evaluation  Cytotoxic activity  Structure-activity relationships  
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载：206/0  |  提交时间：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 234-237
作者:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Ma, Rui-Jing;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao
浏览  |  Adobe PDF(500Kb)  |  收藏  |  浏览/下载：490/217  |  提交时间：2019/03/18
Biodnylated Camptothecin Derivatives  Anticancer Activity  Synthesis  Click Chemistry  Structure-activity Relationships (Sars)  
C21 steroidal glycosides with cytotoxic activities from Cynanchum otophyllum 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 9, 页码: 1520-1524
作者:  Dong, Jinrun;  Peng, Xingrong;  Li, Lei;  Lu, Shuangyang;  Zhou, Lin;  Qiu, Minghua
浏览  |  Adobe PDF(509Kb)  |  收藏  |  浏览/下载：160/49  |  提交时间：2018/07/16
Asclepiadaceae  Cynanchum Otophyllum  C21 Steroidal Glycosides  Cytotoxicities  
Design and synthesis of plant cyclopeptide Astin C analogues and investigation of their immunosuppressive activity 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 14, 页码: 2543-2549
作者:  Li, Fei;  Guo, Xi-Xi;  Zeng, Guang-Zhi;  Qin, Wei-Wei;  Zhang, Bo;  Tan, Ning-Hua
收藏  |  浏览/下载：162/0  |  提交时间：2018/12/27
Synthesis and anti-proliferative activity of allogibberic acid derivatives containing 1,2,3-triazole pharmacophore 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 14, 页码: 2543-2549
作者:  Wu, Ming-Jiang;  Wu, Dong-Mei;  Chen, Jing-Bo;  Zhao, Jing-Feng;  Gong, Liang;  Gong, Ya-Xiao;  Li, Yan;  Yang, Xiao-Dong;  Zhang, Hongbin
收藏  |  浏览/下载：153/0  |  提交时间：2019/03/29
Isocostunolide inhibited glioma stem cell by suppression proliferation and inducing caspase dependent apoptosis 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 页码: 2863-2867
作者:  Dai, Zhi;  Li, Shi-Rong;  Zhu, Pei-Feng;  Liu, Lu;  Wang, Bei;  Liu, Ya-Ping;  Luo, Xiao-Dong;  Zhao, Xu-Dong
浏览  |  Adobe PDF(2209Kb)  |  收藏  |  浏览/下载：305/68  |  提交时间：2017/07/18
Isocostunolide  Glioma Stem Cells  Cell Proliferation  Apoptosis  Colony Formation  
Cytotoxic steroidal saponins from Trillium kamtschaticum 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 页码: 2267-2273
作者:  Qin, Xu-Jie;  Si, Yong-Ai;  Chen, Yu;  Liu, Hui;  Ni, Wei;  Yan, Huan;  Shu, Tong;  Ji, Yun-Heng;  Liu, Hai-Yang
浏览  |  Adobe PDF(529Kb)  |  收藏  |  浏览/下载：266/63  |  提交时间：2017/07/18
Trillium Kamtschaticum  Liliaceae  Steroidal Saponins  Cytotoxicity  
Synthesis and cytotoxic activity of novel tetrahydrobenzodifuran-imidazolium salt derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 8, 页码: 1808-1814
作者:  Zhang, Chao-Bo;  Liu, Yang;  Liu, Zheng-Fen;  Duan, Sheng-Zu;  Li, Min-Yan;  Chen, Wen;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
Adobe PDF(1192Kb)  |  收藏  |  浏览/下载：650/112  |  提交时间：2017/06/30
Tetrahydrobenzodifurans  Imidazolium Salts  Cytotoxic Activity  Cell Cycle  Apoptosis  
Cochlearoids F-K: Phenolic meroterpenoids from the fungus Ganoderma cochlear and their renoprotective activity 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 22, 页码: 5507-5512
作者:  Wang, Xin-Long;  Zhou, Feng-Jiao;  Dou, Man;  Yan, Yong-Ming;  Wang, Shu-Mei;  Di, Lei;  Cheng, Yong-Xian
浏览  |  Adobe PDF(650Kb)  |  收藏  |  浏览/下载：257/66  |  提交时间：2017/01/05
Ganoderma Cochlear  Meroterpenoids  C-13 Nmr Calculations  Renoprotection