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Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 775-787
作者:  Liu, Chin-Yu;  Cheng, Yung-Yi;  Chang, Ling-Chu;  Huang, Li-Jiau;  Chou, Li-Chen;  Huang, Chi-Hung;  Tsai, Meng-Tung;  Liao, Chih-Chang;  Hsu, Mei-Hua;  Lin, Hui-Yi;  Wu, Tian-Shung;  Wen, Yen-Fang;  Zhao, Yu;  Kuo, Sheng-Chu;  Lee, Kuo-Hsiung;  Kuo,SC (reprint author),China Med Univ,Grad Inst Pharmaceut Chem,91 Hsueh Shih Rd,Taichung 40402,Taiwan.;  sckuo@mail.cmu.edu.tw;  khlee@unc.edu
浏览  |  Adobe PDF(1696Kb)  |  收藏  |  浏览/下载：319/74  |  提交时间：2015/06/29
2-arylnaphthyridin-4-ones  Antitumor Agents  Phosphate Prodrug  
Cyclohexane-Fused Octahydroquinolizine Alkaloids from Myrioneuron faberi with Activity against Hepatitis C Virus 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2014, 卷号: 79, 期号: 17, 页码: 7945-7950
作者:  Cao, Ming-Ming;  Zhang, Yu;  Li, Xiao-Hui;  Peng, Zong-Gen;  Jiang, Jian-Dong;  Gu, Yu-Cheng;  Di, Ying-Tong;  Li, Xiao-Nian;  Chen, Duo-Zhi;  Xia, Cheng-Feng;  He, Hong-Ping;  Li, Shun-Lin;  Hao, Xiao-Jiang;  haoxj@mail.kib.ac.cn
Adobe PDF(364Kb)  |  收藏  |  浏览/下载：268/70  |  提交时间：2014/11/25
Biomimetic Synthesis  Nutans  Nitraramine  Skeleton  Therapy  
Diterpenoids with Immunosuppressive Activities from Cinnamomum cassia 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2014, 卷号: 77, 期号: 8, 页码: 1948-1954
作者:  Zeng, Junfen;  Xue, Yongbo;  Shu, Penghua;  Qian, Huiqin;  Sa, Rongjian;  Xiang, Ming;  Li, Xiao-Nian;  Luo, Zengwei;  Yao, Guangmin;  Zhang, Yonghui;  Yao, GM (reprint author), Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Pharm, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Hubei Province, Peoples R China.;  gyap@mail.hust.edu.cn;  zhangyh@mails.tjmu.edu.cn
Adobe PDF(434Kb)  |  收藏  |  浏览/下载：284/75  |  提交时间：2014/10/11
Absolute-configuration  Constituents  Cortex  Glucoside  
Scapiformolactones A-I: Germacrane sesquiterpenoids with an unusual Delta(3)-15,6-lactone moiety from Salvia scapiformis 期刊论文
PHYTOCHEMISTRY, 2013, 卷号: 96, 页码: 378-388
作者:  Lai, Yongji;  Xue, Yongbo;  Zhang, Mengke;  Zhang, Jinwen;  Tang, Wei;  Liu, Junjun;  Lei, Liang;  Yan, Juming;  Luo, Zengwei;  Zuo, Jianping;  Li, Yan;  Yao, Guangmin;  Zhang, Yonghui
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Salvia Scapiformis  Lamiaceae  Germacrane Sesquiterpene  Conformation  Chemical Transformation  Quantum Mechanical Calculation  Cytotoxicity Immunomodulatory Activity  
Antiproliferative Cardiac Glycosides from the Latex of Antiaris toxicaria 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2013, 卷号: 76, 期号: 9, 页码: 1771-1780
作者:  Liu, Qian;  Tang, Jin-Shan;  Hu, Meng-Jie;  Liu, Jie;  Chen, Hai-Feng;  Gao, Hao;  Wang, Guang-Hui;  Li, Shun-Lin;  Hao, Xiao-Jiang;  Zhang, Xiao-Kun;  Yao, Xin-Sheng
Adobe PDF(2429Kb)  |  收藏  |  浏览/下载：194/90  |  提交时间：2015/05/13
Wilsonols A-L, Megastigmane Sesquiterpenoids from the Leaves of Cinnamomum wilsonii 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2013, 卷号: 76, 期号: 7, 页码: 1303-1312
作者:  Shu, Penghua;  Wei, Xialan;  Xue, Yongho;  Li, Weijie;  Zhang, Jinwen;  Xiang, Ming;  Zhang, Mengke;  Luo, Zengwei;  Li, Yan;  Yao, Guangmin;  Zhang, Yonghui
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Apollonias-barbujana  Subavenium  Cassia  C-13-norisoprenoids  Constituents  Glucosides  Glycosides  
Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 13, 页码: 3905-3909
作者:  Yang, Yang;  Yan, Yong-Ming;  Wei, Wei;  Luo, Jie;  Zhang, Lan-Sheng;  Zhou, Xiao-Jiang;  Wang, Peng-Cheng;  Yang, Yong-Xun;  Cheng, Yong-Xian
浏览  |  Adobe PDF(1166Kb)  |  收藏  |  浏览/下载：205/57  |  提交时间：2013/10/16
Anthraquinone  Oxanthrone C-glycoside  Diabetic Nephropathy  Rumex  Endophytic Aspergillus Fumigatus  
Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-kappa B Activation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 11, 页码: 4749-4757
作者:  Zhao, Yu;  Su, Jia;  Goto, Masuo;  Morris-Natschke, Susan L.;  Li, Yan;  Zhao, Qin-Shi;  Yao, Zhu-Jun;  Lee, Kuo-Hsiung
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Natural-products  Biological-activity  Cancer-therapy  Paclitaxel  Taxol  Resistance  Drugs  Chemotherapy  Parthenolide  Brevifoliol  
Evaluation of anti-HCV activity and SAR study of (+)-lycoricidine through targeting of host heat-stress cognate 70 (Hsc70) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 9, 页码: 2679-2682
作者:  Chen, Duo-Zhi;  Jiang, Jian-Dong;  Zhang, Ke-Qing;  He, Hong-Ping;  Di, Ying-Tong;  Zhang, Yu;  Cai, Jie-Yun;  Wang, Lei;  Li, Shun-Lin;  Yi, Ping;  Peng, Zong-Gen;  Hao, Xiao-Jiang
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(+)-lycoricidine  Heat-stress Cognate 70 (Hsc70)  Down-regulators  Structure-activity Relationship (Sar)  Anti-hcv Activity  
Cytotoxic Alkaloids from the Whole Plants of Zephyranthes candida 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2012, 卷号: 75, 期号: 12, 页码: 2113-2120
作者:  Luo, Zengwei;  Wang, Fuqian;  Zhang, Jinwen;  Li, Xingyao;  Zhang, Mengke;  Hao, Xincai;  Xue, Yongbo;  Li, Yan;  Horgen, F. David;  Yao, Guangmin;  Zhang, Yonghui
浏览  |  Adobe PDF(858Kb)  |  收藏  |  浏览/下载：188/61  |  提交时间：2015/06/17