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Pestaloamides A and B, two spiro-heterocyclic alkaloid epimers from the plant endophytic fungus Pestalotiopsis sp. HS30 期刊论文
SCIENCE CHINA-CHEMISTRY, 2020
作者:  Su, Xiao-Zheng;  Zhu, Yi-Ying;  Tang, Jian-Wei;  Hu, Kun;  Li, Xiao-Nian;  Sun, Han-Dong;  Li, Yan;  Puno, Pema-Tenzin
Adobe PDF(858Kb)  |  收藏  |  浏览/下载:133/40  |  提交时间:2021/01/05
Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
Adobe PDF(13632Kb)  |  收藏  |  浏览/下载:278/33  |  提交时间:2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
Targeting peroxiredoxin I potentiates 1,25-dihydroxyvitamin D3-induced cell differentiation in leukemia cells 期刊论文
MOLECULAR MEDICINE REPORTS, 2016, 卷号: 13, 期号: 3, 页码: 2201-2207
作者:  Wei, Wei;  Liu, Chuanxu;  Qin, Dongjun;  Song, Lili;  Xia, Li;  Lei, Hu;  Yu, Yun;  Wang, Weiwei;  Pu, Jianxin;  Sun, Handong;  Wu, Yingli;  Xu, Hanzhang;  Haw, Siguo
Adobe PDF(1039Kb)  |  收藏  |  浏览/下载:182/54  |  提交时间:2016/06/27
Adenanthin  1  25-dihydroxyvitamin D3  Leukemia  Peroxiredoxin i  Cell Differentiation  
Xerophilusin B Induces Cell Cycle Arrest and Apoptosis in Esophageal Squamous Cell Carcinoma Cells and Does Not Cause Toxicity in Nude Mice 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2015, 卷号: 78, 期号: 1, 页码: 10-16
作者:  Yao, Ran;  Chen, Zhaoli;  Zhou, Chengcheng;  Luo, Mei;  Shi, Xuejiao;  Li, Jiagen;  Gao, Yibo;  Zhou, Fang;  Pu, Jianxin;  Sun, Handong;  He, Jie
Adobe PDF(6589Kb)  |  收藏  |  浏览/下载:260/57  |  提交时间:2015/06/29
Cytotoxic cardiac glycosides and coumarins from Antiaris toxicaria 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 6, 页码: 1889-1898
作者:  Shi, Li-Shian;  Kuo, Sheng-Chu;  Sun, Han-Dong;  Morris-Natschke, Susan L.;  Lee, Kuo-Hsiung;  Wu, Tian-Shung
Adobe PDF(537Kb)  |  收藏  |  浏览/下载:506/60  |  提交时间:2014/05/16
Antiaris Toxicaria  Cardiac Glycosides  Coumarins  Cytotoxicity  
Preventive and Therapeutic Effects of Adenanthin on Experimental Autoimmune Encephalomyelitis by Inhibiting NF-kappa B Signaling 期刊论文
JOURNAL OF IMMUNOLOGY, 2013, 卷号: 191, 期号: 5, 页码: 2115-2125
作者:  Yin, Qian-Qian;  Liu, Chuan-Xu;  Wu, Ying-Li;  Wu, Shao-Fang;  Wang, Yan;  Zhang, Xia;  Hu, Xiao-Juan;  Pu, Jian-Xin;  Lu, Ying;  Zhou, Hu-Chen;  Wang, Hong-Lin;  Nie, Hong;  Sun, Han-Dong;  Chen, Guo-Qiang
Adobe PDF(2420Kb)  |  收藏  |  浏览/下载:340/43  |  提交时间:2013/10/16
Autoreactive T-cells  Multiple-sclerosis  Rheumatoid-arthritis  Glatiramer Acetate  Activation  Inflammation  System  Roles  Mice  Differentiation  
Henryin, an ent-kaurane Diterpenoid, Inhibits Wnt Signaling through Interference with beta-Catenin/TCF4 Interaction in Colorectal Cancer Cells 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 7, 页码: e68525
作者:  Li, Xingyao;  Pu, Jianxin;  Jiang, Shiyou;  Su, Jia;  Kong, Lingmei;  Mao, Bingyu;  Sun, Handong;  Li, Yan
Adobe PDF(1775Kb)  |  收藏  |  浏览/下载:541/85  |  提交时间:2013/10/16
Beta-catenin  Colon-cancer  Response Element  Activation  Expression  Pathway  Complex  Growth  Apc  Antagonists  
Discovery of natural estrogen receptor modulators with structure-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 11, 页码: 3329-3333
作者:  Cao, Xianwen;  Jiang, Jing;  Zhang, Shoude;  Zhu, Lili;  Zou, Juan;  Diao, Yanyan;  Xiao, Weilie;  Shan, Lei;  Sun, Handong;  Zhang, Weidong;  Huang, Jin;  Li, Honglin
Adobe PDF(911Kb)  |  收藏  |  浏览/下载:320/92  |  提交时间:2013/07/24
Molecular Docking  Natural Product  Estrogen Receptor  Virtual Screening  
Compounds from the Fruits of the Popular European Medicinal Plant Vitex agnus-castus in Chemoprevention via NADP(H):Quinone Oxidoreductase Type 1 Induction 期刊论文
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2013, 页码: 432829
作者:  Li, Shenghong;  Qiu, Shengxiang;  Yao, Ping;  Sun, Handong;  Fong, Harry H. S.;  Zhang, Hongjie
Adobe PDF(1967Kb)  |  收藏  |  浏览/下载:389/53  |  提交时间:2013/07/24
Constituents  Flavonoids  
Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 卷号: 262, 期号: 1, 页码: 80-90
作者:  Li, Lin;  Yue, Grace G. L.;  Lau, Clara B. S.;  Sun, Handong;  Fung, Kwok Pui;  Leung, Ping Chung;  Han, Quanbin;  Leung, Po Sing
Adobe PDF(2066Kb)  |  收藏  |  浏览/下载:270/60  |  提交时间:2014/04/02
Eriocalyxin b  Pancreatic Cancer  Apoptosis  Cell Cycle Arrest  P53