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Cheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 66689-66699
作者:  Zhang, Ruowen;  Che, Xun;  Zhang, Jingjie;  Li, Yang;  Li, Jingxia;  Deng, Xu;  Zhu, Junlan;  Jin, Honglei;  Zhao, Qinshi;  Huang, Chuanshu
浏览  |  Adobe PDF(9106Kb)  |  收藏  |  浏览/下载：191/44  |  提交时间：2017/01/05
Chel a  Human Bladder Cancer  Apoptosis  Phlpp2  C-jun  
neo-Clerodanes from the aerial parts of Salvia leucantha 期刊论文
TETRAHEDRON, 2016, 卷号: 72, 期号: 35, 页码: 5507-5514
作者:  Jiang, Yong-Jun;  Su, Jia;  Shi, Xin;  Wu, Xing-De;  Chen, Xuan-Qin;  He, Juan;  Shao, Li-Dong;  Li, Xiao-Nian;  Peng, Li-Yan;  Li, Rong-Tao;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1147Kb)  |  收藏  |  浏览/下载：224/46  |  提交时间：2016/11/04
Neo-clerodanes  Salvia Leucantha  Cytotoxicity  Heat Shock Protein 90 Inhibitor  Acetyl Cholinesterase Inhibitory Activity  
Synthesis of hupehenols A, B, and E from protopanaxadiol 期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 42, 页码: 35792-35803
作者:  Shao, Li-Dong;  Xu, Jun;  Li, Xiao-Nian;  Zhang, Zhi-Jun;  Shi, Xin;  Ren, Jian;  He, Juan;  Zhao, Yu;  Leng, Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1402Kb)  |  收藏  |  浏览/下载：208/58  |  提交时间：2016/08/22
Geissoschizine methyl ether N- oxide, a new alkaloid with antiacetylcholinesterase activity from Uncaria rhynchophylla 期刊论文
NATURAL PRODUCT RESEARCH, 2015, 卷号: 29, 期号: 9, 页码: 842-847
作者:  Jiang, Wei-Wei;  Su, Jia;  Wu, Xing-De;  He, Juan;  Peng, Li-Yan;  Cheng, Xiao;  Zhao, Qin-Shi;  Zhao,QS (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Peoples R China.;  qinshizhao@mail.kib.ac.cn
浏览  |  Adobe PDF(711Kb)  |  收藏  |  浏览/下载：264/77  |  提交时间：2015/06/29
Uncaria Rhynchophylla  Rubiaceae  Alkaloids  Geissoschizine Methyl Ether N-oxide  Anti-ache Activity  
Vibsanin B Preferentially Targets HSP90b, Inhibits Interstitial Leukocyte Migration, and Ameliorates Experimental Autoimmune Encephalomyelitis 期刊论文
JOURNAL OF IMMUNOLOGY, 2015, 卷号: 194, 期号: 9, 页码: 4489-4497
作者:  Ye, Bai-Xin;  Deng, Xu;  Shao, Li-Dong;  Lu, Ying;  Xiao, Run;  Liu, Yi-Jie;  Jin, Yi;  Xie, Yin-Yin;  Zhao, Yan;  Luo, Liu-Fei;  Ma, Shun;  Gao, Ming;  Zhang, Lian-Ru;  He, Juan;  Zhang, Wei-Na;  Chen, Yi;  Xia, Cheng-Feng;  Deng, Min;  Liu, Ting-Xi;  Zhao, Qin-Shi;  Chen, Sai-Juan;  Chen, Zhu;  Chen,Z (reprint author),Shanghai Jiao Tong Univ,RuiJin Hosp,Sch Med,197 Rui Jin Rd 2,Shanghai 200025,Peoples R China.;  qinshizhao@mail.kib.ac.cn;  sjchen@stn.sh.cn;  zchen@stn.sh.cn
浏览  |  Adobe PDF(1516Kb)  |  收藏  |  浏览/下载：265/42  |  提交时间：2015/07/20
Crucial Role of c-Jun Phosphorylation at Ser63/73 Mediated by PHLPP Protein Degradation in the Cheliensisin A Inhibition of Cell Transformation 期刊论文
CANCER PREVENTION RESEARCH, 2014, 卷号: 7, 期号: 12, 页码: 1270-1281
作者:  Zhu, Junlan;  Zhang, Jingjie;  Huang, Haishan;  Li, Jingxia;  Yu, Yonghui;  Jin, Honglei;  Li, Yang;  Deng, Xu;  Gao, Jimin;  Zhao, Qinshi;  Huang, Chuanshu;  Huang,CS (reprint author),NYU,Sch Med,Nelson Inst Environm Med,57 Old Forge Rd,Tuxedo Pk,NY 10987 USA.
浏览  |  Adobe PDF(3644Kb)  |  收藏  |  浏览/下载：193/38  |  提交时间：2015/01/20
Naturally Occurring Substances  Magnetic-resonance Spectroscopy  Stem-bark  Melodinus-henryi  Conformational-analysis  (+)-scholarisine  Mechanism  Leaves  Seeds  Camptothecin  Indole Alkaloids  Cytotoxicity  Absolute Configuration  Vinca Major  
Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 3, 页码: 841-852
作者:  Zhang, Jingjie;  Gao, Guangxun;  Chen, Liang;  Li, Jingxia;  Deng, Xu;  Zhao, Qin-shi;  Huang, Chuanshu
Adobe PDF(3282Kb)  |  收藏  |  浏览/下载：290/59  |  提交时间：2014/05/16
Cheliensisin a  Apoptosis  Colon Cancer  P53  Chemotherapeutic Agent  
The Relationships between Chemical and Genetic Differentiation and Environmental Factors across the Distribution of Erigeron breviscapus (Asteraceae) 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 11, 页码: e74490
作者:  Li, Xiang;  Peng, Li-yan;  Zhang, Shu-dong;  Zhao, Qin-shi;  Yi, Ting-shuang
Adobe PDF(516Kb)  |  收藏  |  浏览/下载：276/53  |  提交时间：2014/01/13
Temperature Stress  Aflp  Plant  Acid  Inhibition  Flavonoids  Diversity  Lactuceae  Extract  
Cheliensisin A Inhibits EGF-Induced Cell Transformation with Stabilization of p53 Protein Via a Hydrogen Peroxide/Chk1-Dependent Axis 期刊论文
CANCER PREVENTION RESEARCH, 2013, 卷号: 6, 期号: 9, 页码: 949-958
作者:  Zhang, Jingjie;  Gao, Guangxun;  Chen, Liang;  Deng, Xu;  Li, Jingxia;  Yu, Yonghui;  Zhang, Dongyun;  Li, Fei;  Zhang, Min;  Zhao, Qinshi;  Huang, Chuanshu
Adobe PDF(1677Kb)  |  收藏  |  浏览/下载：2576/231  |  提交时间：2013/10/16
Dna-damage  Cancer Chemoprevention  Induced Phosphorylation  Activation  Apoptosis  Expression  Induction  Hyperoxia  Therapy  Roles  
Melissoidesin G, a diterpenoid purified from Isodon melissoides, induces leukemic-cell apoptosis through induction of redox imbalance and exhibits synergy with other anticancer agents 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2007, 卷号: 121, 期号: 9, 页码: 2084-2094
作者:  Yu, Zu-Yin;  Liang, Yu-Guang;  Xiao, He;  Shan, Ya-Jun;  Dong, Bo;  Huang, Rui;  Fu, Ya-Li;  Zhao, Zhen-Hu;  Liu, Ze-Yuan;  Zhao, Qin-Shi;  Wang, Sheng-Qi;  Chen, Jia-Pei;  Mao, Bing-Zhi;  Cong, Yu-Wen
Adobe PDF(894Kb)  |  收藏  |  浏览/下载：288/78  |  提交时间：2011/11/24
Melissoidesin g  Leukemia  Apoptosis  Redox  Arsenic Trioxide