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Design and synthesis of guaianolide-germacranolide heterodimers as novel anticancer agents against hepatocellular carcinoma 期刊论文
DRUG DEVELOPMENT RESEARCH, 2023
作者:  Yan,Jia-Xin;  Li,Qi-Hao;  Li,Tian-Ze;  Huang,Zhi-Yan;  Ma,Yun-Bao;  Chen,Ji-Jun
浏览  |  Adobe PDF(7663Kb)  |  收藏  |  浏览/下载：11/2  |  提交时间：2024/07/10
antihepatoma effects  guaianolide-germacranolide heterodimers  PDGFRA  DERIVATIVES  
Discovery and Biomimetic Semisynthesis of Spirophyllines A-D from Uncaria rhynchophylla 期刊论文
ORGANIC LETTERS, 2023, 卷号: 25, 期号: 24, 页码: 4434-4438
作者:  Zhou,Hao-Feng;  Li,Wen-Yan;  Wu,Qi;  Ren,Jian;  Peng,Li-Yan;  Li,Xiao-Nian;  Zhao,Qin-Shi
浏览  |  Adobe PDF(2106Kb)  |  收藏  |  浏览/下载：13/4  |  提交时间：2024/07/10
ATRIAL  INHIBITORS  CHANNELS  
A Mushroom P450-Monooxygenase Enables Regioand Stereoselective Biocatalytic Synthesis of Epoxycyclohexenones 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 卷号: 62, 期号: 49
作者:  Yang,Yan-Long;  Zhou,Man;  Yang,Lin;  Gressler,Markus;  Rassbach,Johannes;  Wurlitzer,Jacob M.;  Zeng,Ying;  Gao,Kun;  Hoffmeister,Dirk
Adobe PDF(1998Kb)  |  收藏  |  浏览/下载：25/8  |  提交时间：2024/07/10
Biocatalysis  Biosynthesis  Cytochrome P450  Epoxycyclohexenone  Natural Products  OPPOSITE FACIAL SPECIFICITY  NATURAL-PRODUCTS  STREPTOMYCES LL-C10037  BIOSYNTHESIS  EPOXYQUINONE  CYTOCHROME-P450  FERMENTATION  PANEPOXYDONE  EPOXIDATION  INHIBITION  
Design, synthesis, and biological evaluation of artemyrianolide H derivatives as potential antihepatoma agents 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 137, 页码: 106617
作者:  Li,Tian-Ze;  Yang,Xiao-Tong;  Ma,Wen-Jing;  Ma,Yun-Bao;  Li,Feng-Jiao;  Wang,Yong-Cui;  Chen,Ji-Jun
浏览  |  Adobe PDF(9670Kb)  |  收藏  |  浏览/下载：16/4  |  提交时间：2024/07/22
Artemyrianolide H  Germacranolide derivatives  Antihepatoma activity  Apoptosis  DIMERS  
Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin;  Zuo,Zhili
浏览  |  Adobe PDF(5035Kb)  |  收藏  |  浏览/下载：25/5  |  提交时间：2024/07/22
Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION  
Design and synthesis of ludartin derivatives as potential anticancer agents against hepatocellular carcinoma 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 7, 页码: 1224-1239
作者:  Sun, Jin-Jin;  Wang, Jin-Ping;  Li, Tian-Ze;  Ma, Yun-Bao;  Xue, Dong;  Chen, Ji-Jun
浏览  |  Adobe PDF(1092Kb)  |  收藏  |  浏览/下载：38/8  |  提交时间：2024/04/30
Ludartin derivatives  Antihepatoma activity  HepG2 cells  Huh7 cells  SESQUITERPENE LACTONES  CHEMICAL-CONSTITUENTS  GUAIANOLIDES  ANTITUMOR  ANALOGS  
Synthesis and biological evaluation of (+)-paeoveitol derivatives as novel antidepressants 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 11, 页码: 2045-2057
作者:  Li, Tian-Ze;  Huang, Xiao-Yan;  Sun, Jin-Jin;  Geng, Chang-An;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1234Kb)  |  收藏  |  浏览/下载：52/13  |  提交时间：2024/04/30
(+)-Paeoveitol derivatives  Antidepressant  Forced swimming test  Monoamine neurotransmitter  
Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol derivatives as alpha-glucosidase and PTP1B inhibitors 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 2, 页码: 350-367
作者:  Yang, Xiao-Tong;  Li, Tian-Ze;  Geng, Chang-An;  Liu, Pei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1348Kb)  |  收藏  |  浏览/下载：52/11  |  提交时间：2024/04/30
(20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol  alpha-glucosidase inhibitors  PTP1B inhibitors  Enzyme kinetics  TYROSINE-PHOSPHATASE 1B  DIABETES-MELLITUS  EPIDEMIOLOGY  
Synthesis, Crystal Structures, and Cytotoxic Activity of Two Acetyl Chroman Derivatives 期刊论文
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2022, 卷号: 58, 期号: 12, 页码: 1861-1867
作者:  Hu, X. X.;  Huang, Z. F.;  Lu, G. S.;  Huang, J. Y.;  Li, X. N.;  Tan, X.;  Feng, D.
浏览  |  Adobe PDF(666Kb)  |  收藏  |  浏览/下载：41/11  |  提交时间：2024/04/30
acetyl chroman derivative  X-ray analysis  crystal structures  cytotoxicity  
Uncovering the role of a positive selection site of wax ester synthase/diacylglycerol acyltransferase in two closely related Stipa species in wax ester synthesis under drought stress 期刊论文
JOURNAL OF EXPERIMENTAL BOTANY, 2020
作者:  Yang, Yunqiang;  Zhou, Zhili;  Li, Yan;  Lv, Yanqiu;  Yang, Danni;  Yang, Shihai;  Wu, Jianshuang;  Li, Xiong;  Gu, Zhijia;  Sun, Xudong;  Yang, Yongping
浏览  |  Adobe PDF(3551Kb)  |  收藏  |  浏览/下载：246/62  |  提交时间：2021/01/05