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Crucial Role of c-Jun Phosphorylation at Ser63/73 Mediated by PHLPP Protein Degradation in the Cheliensisin A Inhibition of Cell Transformation 期刊论文
CANCER PREVENTION RESEARCH, 2014, 卷号: 7, 期号: 12, 页码: 1270-1281
作者:  Zhu, Junlan;  Zhang, Jingjie;  Huang, Haishan;  Li, Jingxia;  Yu, Yonghui;  Jin, Honglei;  Li, Yang;  Deng, Xu;  Gao, Jimin;  Zhao, Qinshi;  Huang, Chuanshu;  Huang,CS (reprint author),NYU,Sch Med,Nelson Inst Environm Med,57 Old Forge Rd,Tuxedo Pk,NY 10987 USA.
浏览  |  Adobe PDF(3644Kb)  |  收藏  |  浏览/下载：198/38  |  提交时间：2015/01/20
Naturally Occurring Substances  Magnetic-resonance Spectroscopy  Stem-bark  Melodinus-henryi  Conformational-analysis  (+)-scholarisine  Mechanism  Leaves  Seeds  Camptothecin  Indole Alkaloids  Cytotoxicity  Absolute Configuration  Vinca Major  
Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 20, 页码: 10140-10150
作者:  Zhou, Hongyu;  Shen, Tao;  Shang, Chaowei;  Luo, Yan;  Liu, Lei;  Yan, Juming;  Li, Yan;  Huang, Shile
浏览  |  Adobe PDF(2703Kb)  |  收藏  |  浏览/下载：214/46  |  提交时间：2015/06/17
Ciclopirox  Autophagy  Rhabdomyosarcoma  Reactive Oxygen Species  Jnk  
Adenanthin targets peroxiredoxin I/II to kill hepatocellular carcinoma cells 期刊论文
CELL DEATH & DISEASE, 2014, 卷号: 5, 页码: e1400
作者:  Hou, J-K;  Huang, Y.;  He, W.;  Yan, Z-W;  Fan, L.;  Liu, M-H;  Xiao, W-L;  Sun, H-D;  Chen, G-Q;  Chen,GQ (reprint author),Shandong Jiaotong Univ,Sch Med,Dept Pathophysiol,280 Chong Qing South Rd,Shanghai 200025,Peoples R China.;  huangying@shsmu.edu.cn;  hdsun@mail.kib.ac.cn;  chengq@shsmu.edu.cn
Adobe PDF(4719Kb)  |  收藏  |  浏览/下载：260/64  |  提交时间：2014/11/25
Reactive Oxygen  Cancer-cells  Signaling Pathway  Mechanisms  Apoptosis  Ros  Roles  Death  Prdx1  
Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 7, 页码: e103760
作者:  Kong, Yanjie;  Chen, Jianchao;  Zhou, Zhongmei;  Xia, Houjun;  Qiu, Ming-Hua;  Chen, Ceshi;  Qiu,MH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming,Yunnan,Peoples R China.;  qiuminghua@mail.kib.ac.cn;  chenc@mail.kiz.ac.cn
Adobe PDF(3184Kb)  |  收藏  |  浏览/下载：197/38  |  提交时间：2014/11/25
Inhibitory-activity  Signaling Pathway  Carcinoma  Growth  Activation  
The Mechanism of Poly-Galloyl-Glucoses Preventing Influenza A Virus Entry into Host Cells 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 4, 页码: e94392
作者:  Ge, Hu;  Liu, Ge;  Xiang, Yang-Fei;  Wang, Yu;  Guo, Chao-Wan;  Chen, Nan-Hao;  Zhang, Ying-Jun;  Wang, Yi-Fei;  Kitazato, Kaio;  Xu, Jun
Adobe PDF(4149Kb)  |  收藏  |  浏览/下载：323/55  |  提交时间：2014/06/23
Receptor-binding Properties  Molecular-dynamics  Human Infection  Hemagglutinin  Transmission  Fusion  Origin  Amber  
Cordycepol C Induces Caspase-Independent Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells 期刊论文
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2014, 卷号: 37, 期号: 4, 页码: 608-617
作者:  Sun, Yi-sheng;  Lv, Long-xian;  Zhao, Zhao;  He, Xian;  You, Lu;  Liu, Ji-kai;  Li, Yong-quan
Adobe PDF(3093Kb)  |  收藏  |  浏览/下载：229/56  |  提交时间：2014/05/16
Cordycepol c  Apoptosis  Bax Protein  Apoptosis-inducing Factor  Endonuclease g  
A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30 期刊论文
CELL RESEARCH, 2014, 卷号: 24, 期号: 4, 页码: 482-496
作者:  Yue, Wen;  Chen, Ziheng;  Liu, Haiyang;  Yan, Chen;  Chen, Ming;  Feng, Du;  Yan, Chaojun;  Wu, Hao;  Du, Lei;  Wang, Yueying;  Liu, Jinhua;  Huang, Xiaohu;  Xia, Laixin;  Liu, Lei;  Wang, Xiaohui;  Jin, Haijing;  Wang, Jun;  Song, Zhiyin;  Hao, Xiaojiang;  Chen, Quan
浏览  |  Adobe PDF(1659Kb)  |  收藏  |  浏览/下载：611/56  |  提交时间：2014/05/16
Mitochondrial Fusion  Mitofusin1/2  Deubiquitinase Usp30  15-oxospiramilactone  
The Apoptotic Effect of D Rhamnose beta-Hederin, a Novel Oleanane-Type Triterpenoid Saponin on Breast Cancer Cells 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 3, 页码: e90848
作者:  Cheng, Lin;  Xia, Tian-Song;  Wang, Yi-Fen;  Zhou, Wenbin;  Liang, Xiu-Qing;  Xue, Jin-Qiu;  Shi, Liang;  Wang, Ying;  Ding, Qiang
Adobe PDF(4818Kb)  |  收藏  |  浏览/下载：291/75  |  提交时间：2014/05/16
Oxygen Species Generation  Bcl-2 Family Proteins  Platycodon-grandiflorum  Ginsenoside Rh2  Hepatoma-cells  Mapk Pathways  Anticancer  Activation  Induction  Death  
Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 3, 页码: 841-852
作者:  Zhang, Jingjie;  Gao, Guangxun;  Chen, Liang;  Li, Jingxia;  Deng, Xu;  Zhao, Qin-shi;  Huang, Chuanshu
浏览  |  Adobe PDF(3282Kb)  |  收藏  |  浏览/下载：301/62  |  提交时间：2014/05/16
Cheliensisin a  Apoptosis  Colon Cancer  P53  Chemotherapeutic Agent