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Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 11, 页码: 3576-3589
Authors:  Li, Xue;  Kong, Lingmei;  Yang, Qihong;  Duan, Aizhu;  Ju, Xiaoman;  Cai, Bicheng;  Chen, Lin;  An, Tao;  Li, Yan
Favorite  |  View/Download:4/0  |  Submit date:2020/06/08
small molecule  deubiquitylation (deubiquitination)  Wnt signaling  pharmacology  enzyme inhibitor  ?-catenin  parthenolide  ubiquitination  USP7  Wnt signaling  ubiquitin-specific peptidase 7  colorectal cancer  proteasome system  protein homeostasis  deubiquitinating activity  
Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
Authors:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
View  |  Adobe PDF(1387Kb)  |  Favorite  |  View/Download:51/12  |  Submit date:2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus 期刊论文
OPEN BIOLOGY, 2017, 卷号: 7, 期号: 8, 页码: 170122
Authors:  Ma, Pengcheng;  Ren, Biyu;  Yang, Xiangcai;  Sun, Bin;  Liu, Xiaoliang;  Kong, Qinghua;  Li, Chaocui;  Mao, Bingyu
View  |  Adobe PDF(1985Kb)  |  Favorite  |  View/Download:73/12  |  Submit date:2017/10/23
Zc4h2  Smad  Smurf  Bone Morphogenesis Protein Signalling  Neural Development  
USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2017, 卷号: 131, 期号: 1, 页码: 29-39
Authors:  An, Tao;  Gong, Yaxiao;  Li, Xue;  Kong, Lingmei;  Ma, Pengcheng;  Gong, Liang;  Zhu, Huifang;  Yu, Chunlei;  Liu, Jianmei;  Zhou, Hongyu;  Mao, Bingyu;  Li, Yan
View  |  Adobe PDF(3138Kb)  |  Favorite  |  View/Download:658/117  |  Submit date:2017/04/06
Usp7 Inhibitor  Wnt Signaling  Colorectal Cancer  
USP7 作为结直肠肿瘤治疗靶点的研究 学位论文
: 中国科学院大学, 2017
Authors:  安涛
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CDDO-Me reveals USP7 as a novel target in ovarian cancer cells 期刊论文
Oncotarget, 2016, 卷号: 7, 期号: 47, 页码: 77096-77109
Authors:  Qin, Dongjun;  Wang, Weiwei;  Lei, Hu;  Luo, Hao;  Cai, Haiyan;  Tang, Caixia;  Wu, Yunzhao;  Wang, Yingying;  Jin, Jin;  Xiao, Weilie;  Wang, Tongdan;  Ma, Chunmin;  Xu, Hanzhang;  Zhang, Jinfu;  Gao, Fenghou;  Wu, Ying-Li
View  |  Adobe PDF(8973Kb)  |  Favorite  |  View/Download:75/9  |  Submit date:2017/02/14
Cddo-me  Ovarian Cancer  Usp7  Cetsa  Deubiquitinating Enzymes  
The Ubiquitin Ligase RNF220 Enhances Canonical Wnt Signaling through USP7-Mediated Deubiquitination of beta-Catenin 期刊论文
MOLECULAR AND CELLULAR BIOLOGY, 2014, 卷号: 34, 期号: 23, 页码: 4355-4366
Authors:  Ma, Pengcheng;  Yang, Xiangcai;  Kong, Qinghua;  Li, Chaocui;  Yang, Shuangjuan;  Li, Yan;  Mao, Bingyu;  Mao,BY (reprint author),Kunming Inst Zool,State Key Lab Genet Resources & Evolut,Kunming,Peoples R China.;  mao@mail.kiz.ac.cn
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Stem-cell Fate  Shoot Apical Meristem  Arabidopsis Shoot  Crabs-claw  Nectary Development  Expression  Thaliana  Family  Loop  Polarity  Iayabby2  Ad-abaxial Polarity  Incarvillea Arguta  Arabidopsis Thaliana  
A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30 期刊论文
CELL RESEARCH, 2014, 卷号: 24, 期号: 4, 页码: 482-496
Authors:  Yue, Wen;  Chen, Ziheng;  Liu, Haiyang;  Yan, Chen;  Chen, Ming;  Feng, Du;  Yan, Chaojun;  Wu, Hao;  Du, Lei;  Wang, Yueying;  Liu, Jinhua;  Huang, Xiaohu;  Xia, Laixin;  Liu, Lei;  Wang, Xiaohui;  Jin, Haijing;  Wang, Jun;  Song, Zhiyin;  Hao, Xiaojiang;  Chen, Quan
View  |  Adobe PDF(1659Kb)  |  Favorite  |  View/Download:494/28  |  Submit date:2014/05/16
Mitochondrial Fusion  Mitofusin1/2  Deubiquitinase Usp30  15-oxospiramilactone  
Cordycepol C Induces Caspase-Independent Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells 期刊论文
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2014, 卷号: 37, 期号: 4, 页码: 608-617
Authors:  Sun, Yi-sheng;  Lv, Long-xian;  Zhao, Zhao;  He, Xian;  You, Lu;  Liu, Ji-kai;  Li, Yong-quan
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Cordycepol c  Apoptosis  Bax Protein  Apoptosis-inducing Factor  Endonuclease g  
毛尖紫萼藓GpUCH基因克隆及表达分析 期刊论文
植物分类与资源学报, 2014, 卷号: 36, 期号: 03, 页码: 358-364
Authors:  刘博;  沙伟;  张梅娟;  宋璐;  安洪雪
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