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Pestaloamides A and B, two spiro-heterocyclic alkaloid epimers from the plant endophytic fungus Pestalotiopsis sp. HS30 期刊论文
SCIENCE CHINA-CHEMISTRY, 2020
作者:  Su, Xiao-Zheng;  Zhu, Yi-Ying;  Tang, Jian-Wei;  Hu, Kun;  Li, Xiao-Nian;  Sun, Han-Dong;  Li, Yan;  Puno, Pema-Tenzin
Adobe PDF(858Kb)  |  收藏  |  浏览/下载:130/39  |  提交时间:2021/01/05
Phomopsisins A-C: Three new cytochalasans from the plant endophytic fungus Phomopsis sp. sh917 期刊论文
TETRAHEDRON, 2020
作者:  Tang, Jian-wei;  Hu, Kun;  Su, Xiao-zheng;  Li, Xiao-nian;  Yan, Bing-chao;  Sun, Han-dong;  Puno, Pema-tenzin
Adobe PDF(1170Kb)  |  收藏  |  浏览/下载:122/30  |  提交时间:2021/01/05
Discovery of isopenicin A, a meroterpenoid as a novel inhibitor of tubulin polymerization 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020
作者:  Chen, Lin;  Fan, Dong-Mei;  Tang, Jian-Wei;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Puno, Pema-Tenzin;  Li, Yan
Adobe PDF(1132Kb)  |  收藏  |  浏览/下载:135/43  |  提交时间:2021/01/05
Isorugosiformins A-F, six ent-kaurane diterpenoids from Isodon rugosiformis 期刊论文
FITOTERAPIA, 2020
作者:  Zhang, Qin-Yu;  Yan, Bing-Chao;  Hu, Kun;  Li, Xiao-Nian;  Sun, Han-Dong;  Puno, Pema-Tenzin
Adobe PDF(1626Kb)  |  收藏  |  浏览/下载:109/41  |  提交时间:2021/01/05
Structural determination of eleven new preschisanartane-type schinortriterpenoids from two Schisandra species and structural revision of preschisanartanin J using NMR computation method 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 970-981
作者:  Hu Kun;  Li Xing-Ren;  Tang Jian-Wei;  Li Xiao-Nian;  Puno, Pema-Tenzin
Adobe PDF(1250Kb)  |  收藏  |  浏览/下载:145/43  |  提交时间:2020/03/18
Schisandra sphaerandra  Schisandra rubriflora  Preschisanartane-type schinortriterpenoids  Structural revision  Quantum chemical calculation of NMR parameters  
Isoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scoparius 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 卷号: 21, 期号: 10, 页码: 977-984
作者:  Li, Xing-Ren;  Fu, Qiang;  Zhou, Min;  Hu, Kun;  Du, Xue;  Li, Xiao-Nian;  Sun, Han-Dong;  Yue, Jian-Bo;  Zhang, Hong-Bin;  Puno, Pema-Tenzin
Adobe PDF(1263Kb)  |  收藏  |  浏览/下载:207/45  |  提交时间:2019/10/28
Lamiaceae  ent-clerodane diterpenoids  Isodon scoparius  X-ray diffraction  autophagic activity  
Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors 期刊论文
PHARMACEUTICS, 2019, 卷号: 11, 期号: 9, 页码: 16
作者:  Sajesh, Babu, V;  On, Ngoc H.;  Omar, Refaat;  Alrushaid, Samaa;  Kopec, Brian M.;  Wang, Wei-Guang;  Sun, Han-Dong;  Lillico, Ryan;  Lakowski, Ted M.;  Siahaan, Teruna J.;  Davies, Neal M.;  Puno, Pema-Tenzin;  Vanan, Magimairajan Issai;  Miller, Donald W.
Adobe PDF(3895Kb)  |  收藏  |  浏览/下载:190/47  |  提交时间:2019/12/20
blood-brain barrier (BBB)  drug delivery  transient modulation  HAV6 cadherin peptide  adenanthin  magnetic resonance imaging (MRI)  medulloblastoma  
Structurally diverse diterpenoids from Isodon ternifolius collected from three regions 期刊论文
TETRAHEDRON, 2019, 卷号: 75, 期号: 19, 页码: 2797-2806
作者:  Gou, Lei-Lei;  Hu, Kun;  Yang, Qian;  Li, Xiao-Nian;  Sun, Han-Dong;  Xiang, Chun-Lei;  Puno, Pema-Tenzin
Adobe PDF(1097Kb)  |  收藏  |  浏览/下载:223/40  |  提交时间:2019/06/24
Isodon ternifolius  Diterpenoids  Cytotoxic activity  NMR computation  ECD calculation  
(+)- and (-)-Alternarilactone A: Enantiomers with a Diepoxy-Cage-like Scaffold from an Endophytic Alternaria sp. 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 4, 页码: 735-740
作者:  Tang, Jian-Wei;  Xu, Hou-Chao;  Wang, Wei-Guang;  Hu, Kun;  Zhou, Yuan-Fei;  Chen, Rong;  Li, Xiao-Nian;  Du, Xue;  Sun, Han-Dong;  Puno, Pema-Tenzin
Adobe PDF(1213Kb)  |  收藏  |  浏览/下载:251/35  |  提交时间:2019/06/24
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
Adobe PDF(3457Kb)  |  收藏  |  浏览/下载:281/61  |  提交时间:2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma