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Synthesis and biological evaluation of novel 3-benzylcoumarin-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 4, 页码: 6
作者:  Wang, Xue-Quan;  Chen, Xue-Bing;  Ye, Ping-Ting;  Yang, Zhi-Xin;  Bai, Meng-Jiao;  Duan, Su-Yue;  Li, Yan;  Yang, Xiao-Dong
收藏  |  浏览/下载:156/0  |  提交时间:2020/03/18
3-Benzylcoumarin  Imidazolium salts  Biological evaluation  Cytotoxic activity  Structure-activity relationships  
Chemical and biological comparison of different parts of Paeonia suffruticosa (Mudan) based on LCMS-IT-TOF and multi-evaluation in vitro 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2020, 卷号: 144, 页码: 9
作者:  Pan, Yang;  Gao, Zhen;  Huang, Xiao-Yan;  Chen, Ji-Jun;  Geng, Chang-An
收藏  |  浏览/下载:184/0  |  提交时间:2020/03/24
Paeonia suffruticosa  Chemical profiles  LCMS-IT-TOF analyses  Biological comparison  Neurotransmitter receptors  Enzyme inhibition  
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载:141/0  |  提交时间:2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Glucosides from the Fresh Flowers of Juglans regia L. and Their Biological Evaluation 期刊论文
LETTERS IN ORGANIC CHEMISTRY, 2020, 卷号: 17, 期号: 1, 页码: 31-35
作者:  Wang, Haibo;  Liu, Xikui
收藏  |  浏览/下载:106/0  |  提交时间:2020/03/18
alpha-Tetralonyl glucosides  Juglans regia  juglandaceae  antioxidant  DPPH  antibacterial  
Commiphorines A and B, unprecedented sesquiterpenoid dimers from Resina Commiphora with striking activities on anti-inflammation and lipogenesis inhibition 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 23, 页码: 3825-3833
作者:  Dong, Lu;  Qin, Da-Peng;  Di, Qian-Qian;  Liu, Ying;  Chen, Wei-Lin;  Wang, Shu-Mei;  Cheng, Yong-Xian
浏览  |  Adobe PDF(2250Kb)  |  收藏  |  浏览/下载:148/40  |  提交时间:2020/03/17
Design, Synthesis, and Anticancer Activity of Novel Trimethoxyphenyl-Derived Chalcone-Benzimidazolium Salts 期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 23, 页码: 20381-20393
作者:  Yang, Jun-Li;  Ma, Yong-Hui;  Li, Yan-Hua;  Zhang, Yi-Peng;  Tian, Hong-Chang;  Huang, Yuan-Cheng;  Li, Yan;  Chen, Wen;  Yang, Li-Juan
浏览  |  Adobe PDF(2215Kb)  |  收藏  |  浏览/下载:169/49  |  提交时间:2020/03/18
Identification and Characterization of ShSPI, a Kazal-Type Elastase Inhibitor from the Venom of Scolopendra Hainanum 期刊论文
TOXINS, 2019, 卷号: 11, 期号: 12, 页码: 13
作者:  Luan, Ning;  Zhao, Qiyu;  Duan, Zilei;  Ji, Mengyao;  Xing, Meichen;  Zhu, Tengyu;  Mwangi, James;  Rong, Mingqiang;  Liu, Jiangxin;  Lai, Ren
浏览  |  Adobe PDF(2415Kb)  |  收藏  |  浏览/下载:149/28  |  提交时间:2020/03/18
centipede  kazal-type inhibitor  human neutrophils elastase  ShSPI  
Anti-inflammatory evaluation and structure-activity relationships of diterpenoids isolated from Euphorbia hylonoma 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 10
作者:  Wei, Wen-Jun;  Qi, Weiyan;  Gao, Xin-Mei;  Feng, Ke-Na;  Ma, Kai-Liang;  Li, Hang-Ying;  Li, Ya;  Gao, Kun
浏览  |  Adobe PDF(2502Kb)  |  收藏  |  浏览/下载:158/41  |  提交时间:2020/03/18
Euphorbia hylonoma  ent-Isopimarane  ent-Rosane  Anti-inflammatory  
Homology modeling and 3D-QSAR study of benzhydrylpiperazine delta opioid receptor agonists 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 83, 页码: 9
作者:  Pan, Chenling;  Meng, Hao;  Zhang, Shuqun;  Zuo, Zhili;  Shen, Yuehai;  Wang, Liangliang;  Chang, Kwen-Jen
浏览  |  Adobe PDF(1542Kb)  |  收藏  |  浏览/下载:223/73  |  提交时间:2020/03/18
delta opioid receptor agonists  3D-QSAR  Homology modeling  Molecular dynamics simulation  Molecular docking  
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载:159/28  |  提交时间:2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine