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Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning 期刊论文
CELL REPORTS, 2019, 卷号: 28, 期号: 2, 页码: 541-+
作者:  Ma, Pengcheng;  Song, Ning-Ning;  Li, Yongxin;  Zhang, Qiong;  Zhang, Lei;  Zhang, Longlong;  Kong, Qinghua;  Ma, Li;  Yang, Xiangcai;  Ren, Biyu;  Li, Chaocui;  Zhao, Xudong;  Li, Yan;  Xu, Ying;  Gao, Xiang;  Ding, Yu-Qiang;  Mao, Bingyu
浏览  |  Adobe PDF(5547Kb)  |  收藏  |  浏览/下载:233/42  |  提交时间:2019/08/19
Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
作者:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
浏览  |  Adobe PDF(1387Kb)  |  收藏  |  浏览/下载:254/59  |  提交时间:2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 7, 页码: 10
作者:  Zhang, Yu;  Goto, Masuo;  Oda, Akifumi;  Hsu, Pei-Ling;  Guo, Ling-Li;  Fu, Yan-Hui;  Morris-Natschke, Susan L.;  Hamel, Ernest;  Lee, Kuo-Hsiung;  Hao, Xiao-Jiang
Adobe PDF(3129Kb)  |  收藏  |  浏览/下载:213/23  |  提交时间:2019/07/29
aspidosperma-type  monoterpenoid indole alkaloids  antiproliferative activity  tubulin inhibitor  Bousigonia mekongensis  
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 11
作者:  Liu, Tangjingjun;  Xia, Lei;  Yao, Yao;  Yan, Chen;  Fan, Yanhua;  Gajendran, Babu;  Yang, Jue;  Li, You-Jun;  Chen, Juan;  Filmus, Jorge;  Spaner, David E.;  Zacksenhaus, Eldad;  Hao, Xiaojiang;  Ben-David, Yaacov
Adobe PDF(2055Kb)  |  收藏  |  浏览/下载:268/37  |  提交时间:2019/04/15
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
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Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
12th全国天然有机化学学术会议摘要集 会议录
会议录编者:  中国化学会
Adobe PDF(123481Kb)  |  收藏  |  浏览/下载:176/8  |  提交时间:2018/10/24
Synthesis and anticancer activity of dimeric podophyllotoxin derivatives 期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2018, 卷号: 12, 页码: 3393-3406
作者:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Yang, Dan;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Hu, Jiang-Miao
浏览  |  Adobe PDF(916Kb)  |  收藏  |  浏览/下载:434/98  |  提交时间:2018/11/12
Podophyllotoxin  Dimeric Podophyllotoxin Derivatives  Cuaac Reaction  Perbuty-tylated Glucose  Antitumor  Synthesis  
Potential role of CYP1B1 in the development and treatment of metabolic diseases 期刊论文
PHARMACOLOGY & THERAPEUTICS, 2017, 卷号: 178, 页码: 18-30
作者:  Li, Fei;  Zhu, Weifeng;  Gonzalez, Frank J.
浏览  |  Adobe PDF(2083Kb)  |  收藏  |  浏览/下载:170/54  |  提交时间:2017/11/20
Cyp1b1  Metabolic Diseases  Metabolic Pathways  Metabolomics  
Antioxidants and alpha-glucosidase inhibitors from "Liucha" (young leaves and shoots of Sibiraea laevigata) 期刊论文
FOOD CHEMISTRY, 2017, 卷号: 230, 页码: 117-124
作者:  Zhao, Jian-Qiang;  Wang, Yan-Ming;  Yang, Yan-Long;  Zeng, Ying;  Mei, Li-Juan;  Shi, Yan-Ping;  Tao, Yan-Duo
浏览  |  Adobe PDF(490Kb)  |  收藏  |  浏览/下载:181/40  |  提交时间:2017/08/29
Sibiraea Laevigata  Sorbitol O-caffeic Acid Ester Derivatives  Phenolic Compounds  Antioxidants  Alpha-glucosidase Inhibitors  
Frequent gene flow blurred taxonomic boundaries of sections in Lilium L. (Liliaceae) 期刊论文
PLOS ONE, 2017, 卷号: 12, 期号: 8, 页码: e0183209
作者:  Gong, Xun;  Hung, Kuo-Hsiang;  Ting, Yu-Wei;  Hsu, Tsai-Wen;  Malikova, Lenka;  Huyen Trang Tran;  Huang, Chao-Li;  Liu, Shih-Hui;  Chiang, Tzen-Yuh
浏览  |  Adobe PDF(2899Kb)  |  收藏  |  浏览/下载:201/48  |  提交时间:2017/10/23
Nuclear Ribosomal Dna  Transcribed Spacer Region  Molecular Phylogeny  European Lilies  Sequence Data  Plant Dna  Evolutionary  Chloroplast  Genome  Incongruence