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Two New Anti-Proliferative C-18-Norditerpenes from the Roots of Podocarpus macrophyllus 期刊论文
CHEMISTRY & BIODIVERSITY, 2018, 卷号: 15, 期号: 4, 页码: e1800043
作者:  Qi, Yan-Yan;  Su, Jia;  Zhang, Zhi-Jun;  Li, Lai-Wei;  Fan, Min;  Zhu, Yu;  Wu, Xing-De;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1080Kb)  |  收藏  |  浏览/下载:500/114  |  提交时间:2018/07/02
Podocarpus Macrophyllus  Norditerpenoid  Anti-proliferative Activity  Activity-guided Fractionation  Structure Revision  
Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
浏览  |  Adobe PDF(5724Kb)  |  收藏  |  浏览/下载:387/42  |  提交时间:2017/12/18
Cheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 66689-66699
作者:  Zhang, Ruowen;  Che, Xun;  Zhang, Jingjie;  Li, Yang;  Li, Jingxia;  Deng, Xu;  Zhu, Junlan;  Jin, Honglei;  Zhao, Qinshi;  Huang, Chuanshu
浏览  |  Adobe PDF(9106Kb)  |  收藏  |  浏览/下载:207/45  |  提交时间:2017/01/05
Chel a  Human Bladder Cancer  Apoptosis  Phlpp2  C-jun  
Identification of two novel inhibitors of mTOR signaling pathway based on high content screening 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2013, 卷号: 72, 期号: 4, 页码: 799-808
作者:  Yan, Juming;  Zhou, Hongyu;  Kong, Lingmei;  Zhang, Jing;  Zhao, Qinshi;  Li, Yan
Adobe PDF(1971Kb)  |  收藏  |  浏览/下载:687/105  |  提交时间:2013/11/12
Mtor Signaling  Inhibitor  High Content Screening  Cancer  Apoptosis  
Pseudolaric acid B induces apoptosis via proteasome-mediated Bcl-2 degradation in hormone-refractory prostate cancer DU145 cells 期刊论文
TOXICOLOGY IN VITRO, 2012, 卷号: 26, 期号: 4, 页码: 595-602
作者:  Zhao, Dandan;  Lin, Feng;  Wu, Xingde;  Zhao, Qinshi;  Zhao, Binjiahui;  Lin, Ping;  Zhang, Yanlong;  Yu, Xiaoguang
Adobe PDF(971Kb)  |  收藏  |  浏览/下载:858/174  |  提交时间:2012/06/07
Pseudolaric Acid b  Hormone-refractory Prostate Cancer  Apoptosis  Bcl-2 Degradation  Proteasome  Reactive Oxygen Species  
Inhibition of COX-2 and activation of peroxisome proliferator-activated receptor gamma synergistically inhibits proliferation and induces apoptosis of human pancreatic carcinoma cells 期刊论文
CANCER LETTERS, 2009, 卷号: 275, 期号: 2, 页码: 247-255
作者:  Sun, Wei-Hao;  Chen, Guo-Sheng;  Ou, Xi-Long;  Yang, Ye;  Luo, Cheng;  Zhang, Yuan;  Shao, Yun;  Xu, Hai-Chen;  Xiao, Bin;  Xue, Yi-Ping;  Zhou, Su-Ming;  Zhao, Qin-Shi;  Ding, Guo-Xian
Adobe PDF(635Kb)  |  收藏  |  浏览/下载:1270/371  |  提交时间:2011/12/19
Pancreatic Cancer  Cyclooxygenase-2  Peroxisome Proliferators-activated Receptor  Gamma  Proliferation  Apoptosis  
Blockade of cholecystokinin-2 receptor and cyclooxygenase-2 synergistically induces cell apoptosis, and inhibits the proliferation of human gastric cancer cells in vitro 期刊论文
CANCER LETTERS, 2008, 卷号: 263, 期号: 2, 页码: 302-311
作者:  Sun, Wei-Hao;  Zhu, Feng;  Chen, Guo-Sheng;  Su, Han;  Luo, Cheng;  Zhao, Qin-Shi;  Zhang, Yuan;  Shao, Yun;  Sun, Jian;  Zhou, Su-Ming;  Ding, Guo-Xian;  Cheng, Yun-Lin
Adobe PDF(809Kb)  |  收藏  |  浏览/下载:355/105  |  提交时间:2011/11/24
Cholecystokinin-2 Receptor  Cyclooxygenase-2  Mkn-45 Cell  Proliferation  Apoptosis