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Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载：173/0  |  提交时间：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：193/30  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors 期刊论文
PHARMACEUTICS, 2019, 卷号: 11, 期号: 9, 页码: 16
作者:  Sajesh, Babu, V;  On, Ngoc H.;  Omar, Refaat;  Alrushaid, Samaa;  Kopec, Brian M.;  Wang, Wei-Guang;  Sun, Han-Dong;  Lillico, Ryan;  Lakowski, Ted M.;  Siahaan, Teruna J.;  Davies, Neal M.;  Puno, Pema-Tenzin;  Vanan, Magimairajan Issai;  Miller, Donald W.
浏览  |  Adobe PDF(3895Kb)  |  收藏  |  浏览/下载：206/49  |  提交时间：2019/12/20
blood-brain barrier (BBB)  drug delivery  transient modulation  HAV6 cadherin peptide  adenanthin  magnetic resonance imaging (MRI)  medulloblastoma  
Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning 期刊论文
CELL REPORTS, 2019, 卷号: 28, 期号: 2, 页码: 541-+
作者:  Ma, Pengcheng;  Song, Ning-Ning;  Li, Yongxin;  Zhang, Qiong;  Zhang, Lei;  Zhang, Longlong;  Kong, Qinghua;  Ma, Li;  Yang, Xiangcai;  Ren, Biyu;  Li, Chaocui;  Zhao, Xudong;  Li, Yan;  Xu, Ying;  Gao, Xiang;  Ding, Yu-Qiang;  Mao, Bingyu
浏览  |  Adobe PDF(5547Kb)  |  收藏  |  浏览/下载：238/43  |  提交时间：2019/08/19
Synthesis and Cytotoxicities of Novel Podophyllotoxin Xyloside Derivatives 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2019, 卷号: 14, 期号: 7, 页码: 6
作者:  Zi, Cheng-Ting;  Yang, Liu;  Zhang, Bang-Lei;  Li, Yan;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao;  Zhou, Jun
浏览  |  Adobe PDF(352Kb)  |  收藏  |  浏览/下载：167/35  |  提交时间：2019/09/10
podophyllotoxin  butyrylated xyloside  cytotoxicity  synthesis  
Whole-brain mapping of projection from mouse lateral septal nucleus 期刊论文
BIOLOGY OPEN, 2019, 卷号: 8, 期号: 7, 页码: 9
作者:  Deng, Ke;  Yang, Lu;  Xie, Jing;  Tang, He;  Wu, Gui-Sheng;  Luo, Huai-Rong
浏览  |  Adobe PDF(24131Kb)  |  收藏  |  浏览/下载：196/26  |  提交时间：2019/09/10
Lateral septal nucleus  H129  PRV  Neural circuits  Neural projection  
Prophylactic Effects of Bifidobacterium adolescentis on Anxiety and Depression-Like Phenotypes After Chronic Stress: A Role of the Gut Microbiota-Inflammation Axis 期刊论文
FRONTIERS IN BEHAVIORAL NEUROSCIENCE, 2019, 卷号: 13, 页码: 17
作者:  Guo, Ying;  Xie, Jian-Ping;  Deng, Ke;  Li, Xia;  Yuan, Yun;  Xuan, Qun;  Xie, Jing;  He, Xiao-Ming;  Wang, Qian;  Li, Juan-Juan;  Luo, Huai-Rong
浏览  |  Adobe PDF(4609Kb)  |  收藏  |  浏览/下载：194/29  |  提交时间：2019/07/29
Bifidobacterium adolescentis  antidepressant  chronic restraint stress  gut microbiota  inflammation  
Sense Ginsenosides From Ginsengs: Structure-Activity Relationship in Autophagy 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2019, 卷号: 14, 期号: 6, 页码: 10
作者:  Wu, Tao;  Kwaku, Osafo Raymond;  Li, Hai-Zhou;  Yang, Chong-Ren;  Ge, Long-Jiao;  Xu, Min
浏览  |  Adobe PDF(1069Kb)  |  收藏  |  浏览/下载：172/37  |  提交时间：2019/09/10
ginsengs  ginsenosides  structure-activity relationship  autophagy  
The sources and mechanisms of bioactive ingredients in coffee 期刊论文
FOOD & FUNCTION, 2019, 卷号: 10, 期号: 6, 页码: 3113-3126
作者:  Hu, G. L.;  Wang, X.;  Zhang, L.;  Qiu, M. H.
浏览  |  Adobe PDF(2231Kb)  |  收藏  |  浏览/下载：190/54  |  提交时间：2019/09/10
Sesquiterpenoids from the roots and rhizomes of Valeriana amurensis and their effects on NGF-induced neurite outgrowth in PC12 cells 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 页码: 6
作者:  Dong, Fa-Wu;  Li, Fang;  Ren, Jia-Jia;  Zhao, Cheng-Mei;  Diao, Hong-Li;  Li, Bao-Jing;  Li, Yan-Ping;  Hu, Jiang-Miao;  He, Hong-Ping
浏览  |  Adobe PDF(798Kb)  |  收藏  |  浏览/下载：148/36  |  提交时间：2019/07/29
Valeriana amurensis  sesquiterpenoids  central nervous system  PC12 cells