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Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 8
作者:  Huang, Jian-Ping;  Fang, Chengli;  Ma, Xiaoyan;  Wang, Li;  Yang, Jing;  Luo, Jianying;  Yan, Yijun;  Zhang, Yu;  Huang, Sheng-Xiong
浏览  |  Adobe PDF(1048Kb)  |  收藏  |  浏览/下载:212/51  |  提交时间:2019/10/28
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载:312/37  |  提交时间:2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
A billion cups: The diversity, traditional uses, safety issues and potential of Chinese herbal teas 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 222, 页码: 217-228
作者:  Fu, Yao;  Yang, Jin-chao;  Cunningham, Anthony B.;  Towns, Alexandra Maria;  Zhang, Yu;  Yang, Hua-ying;  Li, Jian-wen;  Yang, Xue-fei
浏览  |  Adobe PDF(1409Kb)  |  收藏  |  浏览/下载:178/66  |  提交时间:2019/03/29
Autocatalytic synthesis of 3-ethyl-3-hydroxy-indole-2-ones and their neuroprotection and antitumor activities' evaluation 期刊论文
COMPTES RENDUS CHIMIE, 2018, 卷号: 21, 期号: 5, 页码: 471-474
作者:  Chen, Gang;  Lin, Jiao;  Zhang, Jie;  Wu, Ya;  Gu, Xuefan;  Hao, Xiaojiang;  Zhang, Yu
收藏  |  浏览/下载:126/0  |  提交时间:2019/03/29
Isatin  3-Ethyl-3-hydroxy-indole-2-one  Antitumor  Neuroprotection  
Synthesis, Neuro-protection and Anti-cancer Activities of Simple Isatin Mannich and Schiff Bases 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2016, 卷号: 13, 期号: 5, 页码: 395-400
作者:  Chen, Gang;  Ning, Yang;  Zhao, Wei;  Zhang, Yanqiu;  Zhang, Yu;  Hao, Xiaojiang;  Wang, Ye;  Mu, Shuzhen
浏览  |  Adobe PDF(1361Kb)  |  收藏  |  浏览/下载:233/70  |  提交时间:2016/08/22
Isatin  Mannich Base  Schiff Base  Synthesis  Neuro-protection  Anti-tumor  
Theoretical study of regioselectivity in the synthesis of spiro [pyrrolidine-2,3'-oxindole] compounds by [3+2] cycloaddition 期刊论文
RESEARCH ON CHEMICAL INTERMEDIATES, 2015, 卷号: 41, 期号: 7, 页码: 4987-4996
作者:  Chen, Gang;  Yang, Jing;  Gao, Suo;  Zhang, Yu;  Hao, Xiaojiang
Adobe PDF(1404Kb)  |  收藏  |  浏览/下载:150/39  |  提交时间:2015/12/17
Regioselectivity  Theoretical  Spiro-oxindole  [3+2] Cycloaddition  
Unprecedented Quassinoids with Promising Biological Activity from Harrisonia perforata 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 卷号: 54, 期号: 19, 页码: 5592-5595
作者:  Fang, Xin;  Di, Ying Tong;  Zhang, Yu;  Xu, Zhi Ping;  Lu, Yang;  Chen, Qian Qian;  Zheng, Qi Tai;  Hao, Xiao Jiang;  Hao,XJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  haoxj@mail.kib.ac.cn
浏览  |  Adobe PDF(931Kb)  |  收藏  |  浏览/下载:301/103  |  提交时间:2015/07/20
Biosynthetic Pathways  Insecticidal Activity  Natural Products  Nicotinic Acetylcholine Receptors  Structure Elucidation  
Lycorine-derived phenanthridine downregulators of host Hsc70 as potential hepatitis C virus inhibitors 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2015, 卷号: 7, 期号: 5, 页码: 561-570
作者:  Chen, Duozhi;  Cai, Jieyun;  Yin, Junlin;  Jiang, Jiandong;  Jing, Chenxu;  Zhu, Yanping;  Cheng, Junjun;  Di, Yingtong;  Zhang, Yu;  Cao, Mingming;  Li, Shunlin;  Peng, Zonggen;  Hao, Xiaojiang;  Hao,XJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  haoxj@mail.kib.ac.cn
浏览  |  Adobe PDF(1560Kb)  |  收藏  |  浏览/下载:291/54  |  提交时间:2015/07/20
Synthesis, Cytoprotective and Anti-tumor Activities of Isatin Schiff Bases 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2015, 卷号: 12, 期号: 10, 页码: 802-805
作者:  Chen, Gang;  Meng, Mei;  Zhang, Yu;  Hao, Xiaojiang;  Wang, Ye;  Mu, Shuzhen
浏览  |  Adobe PDF(1108Kb)  |  收藏  |  浏览/下载:139/38  |  提交时间:2016/01/19
Isatin  Synthesis  Schiff Base  Structure  Cytoprotective  Anti-tumor  
Indole alkaloids from cultivated Vinca major 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 45, 页码: 8723-8729
作者:  Cheng, Gui-Guang;  Zhao, Yun-Li;  Zhang, Yu;  Lunga, Paul-Keilah;  Hu, Dong-Bao;  Li, Yan;  Gu, Ji;  Song, Chang-Wei;  Sun, Wei-Bang;  Liu, Ya-Ping;  Luo, Xiao-Dong;  Liu,YP (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  liuyaping@mail.kib.ac.cn;  xdluo@mail.kib.ac.cn
浏览  |  Adobe PDF(690Kb)  |  收藏  |  浏览/下载:433/156  |  提交时间:2015/01/20
Indole Alkaloids  Cytotoxicity  Absolute Configuration  Vinca Major