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Melocochines A and B, Two Alkaloids from the Fruits of Melodinus cochinchinensis 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 22, 页码: 9272-9275
作者:  Zhang, Yu;  Ding, Xiao;  Shao, Shun;  Guo, Ling-Li;  Zhao, Qing;  Hao, Xiao-Jiang;  He, Hong-Ping
浏览  |  Adobe PDF(982Kb)  |  收藏  |  浏览/下载:345/187  |  提交时间:2020/03/02
12 beta-Acetyloxyperforatin, a New Limonoid from Harrisonia Perforata 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 卷号: 33, 期号: 19, 页码: 2830-2836
作者:  Gui, Peng-Yan;  Yan, Xiao-Hui;  Yuan, Wen-Juan;  Ma, Yuan-Liang;  Ding, Xiao;  Liu, Shuai;  Di, Ying-Tong;  Zhu, Wei-Ming;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(919Kb)  |  收藏  |  浏览/下载:381/174  |  提交时间:2019/09/10
Harrisonia perforata  limonoid  12 beta-Acetyloxyperforatin  computational modelling  
A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 页码: 9
作者:  Adelakun, Tiwalade A.;  Ding, Xiao;  Ombati, Rose M.;  Zhao, Ning-Dong;  Obodozie-Ofoegbu, Obiageri;  Di, Ying-Tong;  Zhang, Yu;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1037Kb)  |  收藏  |  浏览/下载:329/162  |  提交时间:2019/07/29
Euphorbia fischeriana Steud  highly oxygenated abietanes  phorbol esters  lysosomal biogenesis  
Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 7, 页码: 10
作者:  Zhang, Yu;  Goto, Masuo;  Oda, Akifumi;  Hsu, Pei-Ling;  Guo, Ling-Li;  Fu, Yan-Hui;  Morris-Natschke, Susan L.;  Hamel, Ernest;  Lee, Kuo-Hsiung;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3129Kb)  |  收藏  |  浏览/下载:240/27  |  提交时间:2019/07/29
aspidosperma-type  monoterpenoid indole alkaloids  antiproliferative activity  tubulin inhibitor  Bousigonia mekongensis  
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载:336/44  |  提交时间:2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 11
作者:  Liu, Tangjingjun;  Xia, Lei;  Yao, Yao;  Yan, Chen;  Fan, Yanhua;  Gajendran, Babu;  Yang, Jue;  Li, You-Jun;  Chen, Juan;  Filmus, Jorge;  Spaner, David E.;  Zacksenhaus, Eldad;  Hao, Xiaojiang;  Ben-David, Yaacov
浏览  |  Adobe PDF(2055Kb)  |  收藏  |  浏览/下载:283/40  |  提交时间:2019/04/15
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
浏览  |  Adobe PDF(2607Kb)  |  收藏  |  浏览/下载:302/50  |  提交时间:2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
C. elegans-based screen identifies lysosome-damaging alkaloids that induce STAT3-dependent lysosomal cell death 期刊论文
PROTEIN & CELL, 2018, 卷号: 9, 期号: 12, 页码: 1013-1026
作者:  Li, Yang;  Zhang, Yu;  Gan, Qiwen;  Xu, Meng;  Ding, Xiao;  Tang, Guihua;  Liang, Jingjing;  Liu, Kai;  Liu, Xuezhao;  Wang, Xin;  Guo, Lingli;  Gao, Zhiyang;  Hao, Xiaojiang;  Yang, Chonglin
收藏  |  浏览/下载:111/0  |  提交时间:2019/03/29
Integrating transcriptome and microRNA analysis identifies genes and microRNAs for AHO-induced systemic acquired resistance in N-tabacum 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 12504
作者:  Chen, Yongdui;  Dong, Jiahong;  Bennetzen, Jeffrey L.;  Zhong, Micai;  Yang, Jun;  Zhang, Jie;  Li, Shunlin;  Hao, Xiaojiang;  Zhang, Zhongkai;  Wang, Xuewen
浏览  |  Adobe PDF(3093Kb)  |  收藏  |  浏览/下载:353/68  |  提交时间:2017/10/23
Plant Innate Immunity  Acibenzolar-s-methyl  Flue-cured Tobacco  Salicylic-acid  Small Rnas  Stress Responses  Expression  Arabidopsis  Target  Mirna  
Anti-HIV Activities and Mechanism of 12-O-Tricosanoylphorbol-20-acetate, a Novel Phorbol Ester from Ostodes katharinae 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 9, 页码: 1498
作者:  Chen, Huan;  Zhang, Rong;  Luo, Rong-Hua;  Yang, Liu-Meng;  Wang, Rui-Rui;  Hao, Xiao-Jiang;  Zheng, Yong-Tang
浏览  |  Adobe PDF(1939Kb)  |  收藏  |  浏览/下载:214/42  |  提交时间:2017/10/23
Antiviral Agent  12-o-tricosanoylphorbol-20-acetate  Hiv  Vif  Apobec3g  Phorbol Ester