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Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(9057Kb)  |  收藏  |  浏览/下载：225/45  |  提交时间：2020/03/26
Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 8
作者:  Huang, Jian-Ping;  Fang, Chengli;  Ma, Xiaoyan;  Wang, Li;  Yang, Jing;  Luo, Jianying;  Yan, Yijun;  Zhang, Yu;  Huang, Sheng-Xiong
浏览  |  Adobe PDF(1048Kb)  |  收藏  |  浏览/下载：232/57  |  提交时间：2019/10/28
Community Structures and Antifungal Activity of Root-Associated Endophytic Actinobacteria of Healthy and Diseased Soybean 期刊论文
MICROORGANISMS, 2019, 卷号: 7, 期号: 8, 页码: 15
作者:  Liu, Chongxi;  Zhuang, Xiaoxin;  Yu, Zhiyin;  Wang, Zhiyan;  Wang, Yongjiang;  Guo, Xiaowei;  Xiang, Wensheng;  Huang, Shengxiong
浏览  |  Adobe PDF(1295Kb)  |  收藏  |  浏览/下载：237/51  |  提交时间：2019/10/28
Sclerotinia sclerotiorum (Lib  ) de Bary  diseased soybean root  antifungal activity  actinobacterial community  new agroactive compounds  
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
作者:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(3915Kb)  |  收藏  |  浏览/下载：244/41  |  提交时间：2019/07/29
Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 79, 页码: 165-176
作者:  Li, Yingying;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Liu, Xingyong;  Zhang, Li;  Wang, Liang-Liang;  Zuo, Zhili
浏览  |  Adobe PDF(7335Kb)  |  收藏  |  浏览/下载：252/28  |  提交时间：2019/07/29
Pharmacophore modeling  Molecular docking  Quantitative structure activity relationship (QSAR)  Molecular dynamics  AMPK  Activator  
Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling 期刊论文
MOLECULAR & CELLULAR PROTEOMICS, 2019, 卷号: 18, 期号: 3, 页码: 520-533
作者:  Zhao, Qi;  Liu, Fang;  Cheng, Yan;  Xiao, Xue-Rong;  Hu, Dan-Dan;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(4782Kb)  |  收藏  |  浏览/下载：185/61  |  提交时间：2019/07/29
Modulation of Lipid Metabolism by Celastrol 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 1133-1144
作者:  Zhang, Ting;  Zhao, Qi;  Xiao, Xuerong;  Yang, Rui;  Hu, Dandan;  Zhu, Xu;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(5774Kb)  |  收藏  |  浏览/下载：320/68  |  提交时间：2019/04/15
celastrol  lipidomics  hyperlipidemia  LC-MS  
Statistically correlating NMR spectra and LC-MS data to facilitate the identification of individual metabolites in metabolomics mixtures 期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2019, 卷号: 411, 期号: 7, 页码: 1301-1309
作者:  Li, Xing;  Luo, Huan;  Huang, Tao;  Xu, Li;  Shi, Xiaohuo;  Hu, Kaifeng
浏览  |  Adobe PDF(1588Kb)  |  收藏  |  浏览/下载：201/48  |  提交时间：2019/07/29
Deconvolution  LC-MS  NMR  Statistical correlation  Structure identification  
Discovery of novel indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors by virtual screening 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 78, 页码: 306-316
作者:  Zhou, Yeheng;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Li, Yingying;  Zhang, Li;  Sun, Wei;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(2732Kb)  |  收藏  |  浏览/下载：265/42  |  提交时间：2019/03/25
IDO1  Molecular docking  HipHop pharmacophore  3D-QSAR  PAINS  
The Effects of Age and Reproduction on the Lipidome of Caenorhabditis elegans 期刊论文
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2019, 页码: 14
作者:  Wan, Qin-Li;  Yang, Zhong-Lin;  Zhou, Xiao-Gang;  Ding, Ai-Jun;  Pu, Yuan-Zhu;  Luo, Huai-Rong;  Wu, Gui-Sheng
浏览  |  Adobe PDF(2720Kb)  |  收藏  |  浏览/下载：185/24  |  提交时间：2019/07/29