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Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol derivatives as alpha-glucosidase and PTP1B inhibitors 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 2, 页码: 350-367
作者:  Yang, Xiao-Tong;  Li, Tian-Ze;  Geng, Chang-An;  Liu, Pei;  Chen, Ji-Jun
Adobe PDF(1348Kb)  |  收藏  |  浏览/下载：34/8  |  提交时间：2024/04/30
(20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol  alpha-glucosidase inhibitors  PTP1B inhibitors  Enzyme kinetics  TYROSINE-PHOSPHATASE 1B  DIABETES-MELLITUS  EPIDEMIOLOGY  
Structure Revision of Four Classes of Prenylated Aromatic Natural Products Based on a Rule for Diagnostic C-13 NMR Chemical Shifts 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 16, 页码: 10982-10990
作者:  Ren,Fu-Cai;  Wang,Li-Xia;  Lv,Yong-Feng;  Hu,Jiang-Miao;  Zhou,Jun
Adobe PDF(1507Kb)  |  收藏  |  浏览/下载：104/39  |  提交时间：2022/04/02
ISOPRENYLATED FLAVONOIDS  CONSTITUENTS  DERIVATIVES  ANALOGS  
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Huang,Xiao-Yan;  Zhang,Xue-Mei;  Guo,Yuan-Qiang;  Geng,Chang-An
Adobe PDF(2762Kb)  |  收藏  |  浏览/下载：143/60  |  提交时间：2022/04/02
Alpinia katsumadai  Katsumadainols B-1-B-15  Natural products  Structure elucidation  Biological activity  TYROSINE-PHOSPHATASE 1B  GLYCOGEN-PHOSPHORYLASE  ALPHA-GLUCOSIDASE  ABSOLUTE-CONFIGURATION  STRUCTURE ELUCIDATION  DUAL INHIBITION  SEEDS  CONSTITUENT  DERIVATIVES  CHALCONE  
Six New 3,5-Dimethylcoumarins from Chelonopsis praecox, Chelonopsis odontochila and Chelonopsis pseudobracteata. 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 6, 页码: 643-649
作者:  Geng,Chang-An;  Deng,Zhen-Tao;  Huang,Qian;  Xiang,Chun-Lei;  Chen,Ji-Jun
Adobe PDF(893Kb)  |  收藏  |  浏览/下载：77/5  |  提交时间：2022/04/02
Chemical profiling and antidiabetic potency of Paeonia delavayi: Comparison between different parts and constituents 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 113998
作者:  Huang,Qian;  Chen,Ji-Jun;  Pan,Yang;  He,Xiao-Feng;  Wang,Yuan;  Zhang,Xue-Mei;  Geng,Chang-An
Adobe PDF(2388Kb)  |  收藏  |  浏览/下载：71/10  |  提交时间：2022/04/02
Paeonia delavayi  Chemical comparison  LCMS analyses  Antidiabetic effects  PTP1B/TCPTP selective inhibitors  LIQUID-CHROMATOGRAPHY  MULTIPLE CONSTITUENTS  RAPID IDENTIFICATION  GLYCOSIDES  ROOT  DERIVATIVES  TARGETS  CAPSULE  L.  
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
Adobe PDF(5184Kb)  |  收藏  |  浏览/下载：94/25  |  提交时间：2022/04/02
Amomum tsao-ko  Amomutsaokins A-H  Flavanol-menthane conjugates  PTP1B selective inhibitors  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  TANNINS  CREVOST  ACID  
Diarylheptanoid-chalcone hybrids with PTP1B and alpha-glucosidase dual inhibition from Alpinia katsumadai 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104683
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Zhang,Xue-Mei;  Geng,Chang-An
Adobe PDF(2223Kb)  |  收藏  |  浏览/下载：131/53  |  提交时间：2022/04/02
Alpinia katsumadai  Katsumadainols A(1)-A(16)  PTP1B/TCPTP selective inhibitors  alpha-glucosidase inhibitors  Antidiabetic effects  THEORETICAL CALCULATION  ABSOLUTE-CONFIGURATION  SEEDS  BLEPHAROCALYXINS  ADDUCT  MOIETY  
Diterpenoids and Sesquiterpenoids from Syzygium fluviatile 期刊论文
RECORDS OF NATURAL PRODUCTS, 2020
作者:  Zhang, Dingli;  Hu, Yikao;  Wang, Li;  Huang, Shengxiong;  Zhao, Yan;  Li, Mengjia;  Li, Feng;  Zhao, Yong
Adobe PDF(900Kb)  |  收藏  |  浏览/下载：157/23  |  提交时间：2021/01/05
Resorcinol derivatives with alpha-glucosidase inhibitory activities from Syzygium samarangense 期刊论文
NATURAL PRODUCT RESEARCH, 2020
作者:  Hu, Yi-Kao;  Wang, Li;  Wang, Ji-Hua;  Li, Meng-Jia;  Li, Feng;  Yang, Jing;  Zhao, Yong
Adobe PDF(916Kb)  |  收藏  |  浏览/下载：122/33  |  提交时间：2021/01/05
Five new phloroglucinol derivatives from Syzygium brachyantherum and their alpha-glucosidase and PTP1B inhibitory activities 期刊论文
NATURAL PRODUCT RESEARCH, 2020
作者:  Xu, Wen;  Xu, Shao-Hua;  Wang, Li;  Zang, Zhen;  Zhao, Yan;  Liu, Jing-Ping;  Yang, Jing;  Zhao, Yong
Adobe PDF(1035Kb)  |  收藏  |  浏览/下载：129/27  |  提交时间：2021/01/05