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Crucial Role of c-Jun Phosphorylation at Ser63/73 Mediated by PHLPP Protein Degradation in the Cheliensisin A Inhibition of Cell Transformation 期刊论文
CANCER PREVENTION RESEARCH, 2014, 卷号: 7, 期号: 12, 页码: 1270-1281
作者:  Zhu, Junlan;  Zhang, Jingjie;  Huang, Haishan;  Li, Jingxia;  Yu, Yonghui;  Jin, Honglei;  Li, Yang;  Deng, Xu;  Gao, Jimin;  Zhao, Qinshi;  Huang, Chuanshu;  Huang,CS (reprint author),NYU,Sch Med,Nelson Inst Environm Med,57 Old Forge Rd,Tuxedo Pk,NY 10987 USA.
浏览  |  Adobe PDF(3644Kb)  |  收藏  |  浏览/下载：199/38  |  提交时间：2015/01/20
Naturally Occurring Substances  Magnetic-resonance Spectroscopy  Stem-bark  Melodinus-henryi  Conformational-analysis  (+)-scholarisine  Mechanism  Leaves  Seeds  Camptothecin  Indole Alkaloids  Cytotoxicity  Absolute Configuration  Vinca Major  
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi;  Li, Yan
浏览  |  Adobe PDF(3014Kb)  |  收藏  |  浏览/下载：280/71  |  提交时间：2015/06/17
Erib  Activity-based Probes  P50  Nf-kappa b Signaling  Apoptosis  
Synthesis and cytotoxic activity of novel 1-((indol-3-yl)methyl)-1H-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 21, 页码: 4926-4930
作者:  Xu, Xiao-Liang;  Wang, Jia;  Yu, Chun-Lei;  Chen, Wen;  Li, Ying-Chao;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong;  Li,Y (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Peoples R China.;  liyanb@mail.kib.ac.cn;  zhanghbyd@gmail.com;  xdyang@ynu.edu.cn
Adobe PDF(670Kb)  |  收藏  |  浏览/下载：379/90  |  提交时间：2014/11/25
Indole  Imidazolium Salts  Structure-activity Relationships  Cell Apoptosis  
Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 20, 页码: 10140-10150
作者:  Zhou, Hongyu;  Shen, Tao;  Shang, Chaowei;  Luo, Yan;  Liu, Lei;  Yan, Juming;  Li, Yan;  Huang, Shile
浏览  |  Adobe PDF(2703Kb)  |  收藏  |  浏览/下载：214/46  |  提交时间：2015/06/17
Ciclopirox  Autophagy  Rhabdomyosarcoma  Reactive Oxygen Species  Jnk  
Phragmalin Limonoids from the Stem Barks of Chukrasia tabularis var. velutina 期刊论文
PLANTA MEDICA, 2014, 卷号: 80, 期号: 15, 页码: 1304-1309
作者:  Yin, Jun-Lin;  Fang, Xin;  Liu, En-De;  Yuan, Chun-Mao;  Li, Shi-Fei;  Zhang, Yu;  He, Hong-Ping;  Li, Shun-Lin;  Di, Ying-Tong;  Hao, Xiao-Jiang;  Hao,XJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,132 Lanhei Rd,Kunming 650201,Peoples R China.;  diyt@mail.kib.ac.cn;  haoxj@mail.kib.ac.cn
Adobe PDF(128Kb)  |  收藏  |  浏览/下载：276/79  |  提交时间：2014/11/25
Chukrasia Tabularis  Meliaceae  Phragmalin  Limonoid  Chukvelutilide i  Artemia Sinica  
Adenanthin targets peroxiredoxin I/II to kill hepatocellular carcinoma cells 期刊论文
CELL DEATH & DISEASE, 2014, 卷号: 5, 页码: e1400
作者:  Hou, J-K;  Huang, Y.;  He, W.;  Yan, Z-W;  Fan, L.;  Liu, M-H;  Xiao, W-L;  Sun, H-D;  Chen, G-Q;  Chen,GQ (reprint author),Shandong Jiaotong Univ,Sch Med,Dept Pathophysiol,280 Chong Qing South Rd,Shanghai 200025,Peoples R China.;  huangying@shsmu.edu.cn;  hdsun@mail.kib.ac.cn;  chengq@shsmu.edu.cn
Adobe PDF(4719Kb)  |  收藏  |  浏览/下载：261/65  |  提交时间：2014/11/25
Reactive Oxygen  Cancer-cells  Signaling Pathway  Mechanisms  Apoptosis  Ros  Roles  Death  Prdx1  
Peganumine A, a beta-Carboline Dimer with a New Octacyclic Scaffold from Peganum harmala 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 15, 页码: 4028-4031
作者:  Wang, Kai-Bo;  Di, Ying-Tong;  Bao, Yu;  Yuan, Chun-Mao;  Chen, Gang;  Li, Da-Hong;  Bai, Jiao;  He, Hong-Ping;  Hao, Xiao-Jiang;  Pei, Yue-Hu;  Jing, Yong-Kui;  Li, Zhan-Lin;  Hua, Hui-Ming;  Li, ZL (reprint author), Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Liaoning, Peoples R China.;  lzl1030@hotmail.com;  huimhua@163.com
浏览  |  Adobe PDF(295Kb)  |  收藏  |  浏览/下载：312/92  |  提交时间：2014/10/11
Light-emitting-diodes  Alkaloid Extract  Potent  L.  Derivatives  Efficiency  Toxicity  Harmine  Cascade  Growth  
Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 7, 页码: e103760
作者:  Kong, Yanjie;  Chen, Jianchao;  Zhou, Zhongmei;  Xia, Houjun;  Qiu, Ming-Hua;  Chen, Ceshi;  Qiu,MH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming,Yunnan,Peoples R China.;  qiuminghua@mail.kib.ac.cn;  chenc@mail.kiz.ac.cn
Adobe PDF(3184Kb)  |  收藏  |  浏览/下载：197/38  |  提交时间：2014/11/25
Inhibitory-activity  Signaling Pathway  Carcinoma  Growth  Activation  
Self-Organizing Maps for the Classification of Gallic Acylate Polyphenols as HSV-1 Inhibitors 期刊论文
MEDICINAL CHEMISTRY, 2014, 卷号: 10, 期号: 4, 页码: 388-401
作者:  Qiu, Xianxiu;  Zhong, Meigong;  Xiang, Yangfei;  Qu, Chang;  Pei, Ying;  Zhang, Yingjun;  Yang, Chongren;  Gasteiger, Johann;  Xu, Jun;  Liu, Zhong;  Wang, Yifei
Adobe PDF(1068Kb)  |  收藏  |  浏览/下载：323/74  |  提交时间：2014/06/23
Artificial Neural Network  Counterpropagation Neural Networks  Gallic Acylate Polyphenol  Herpes Simplex Viruses  Self-organizing Maps  Structure-activity Relationship  
Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 10, 页码: 2353-2359
作者:  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Zhao, Yong;  Wang, Li-Jun;  Guo, Rui-Hua;  Liang, Wen-Juan;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(3861Kb)  |  收藏  |  浏览/下载：305/73  |  提交时间：2014/06/23
Anti-hbv Activity  DehydroAndrographolide And  Andrographolide Derivatives  Structure-activity Relationships  Octanol-water Partition Coefficients