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The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
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glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 9, 页码: 14
作者:  Guo, Di;  Wang, Yurong;  Wang, Jing;  Song, Lihua;  Wang, Zhe;  Mao, Bingyu;  Tan, Ninghua
浏览  |  Adobe PDF(9639Kb)  |  收藏  |  浏览/下载：165/32  |  提交时间：2019/07/29
RA-XII  lipogenesis  SCAP  SREBP  liver cancer  
Novel dual-color drug screening model for GLUT4 translocation in adipocytes 期刊论文
MOLECULAR AND CELLULAR PROBES, 2019, 卷号: 43, 页码: 6-12
作者:  Lu, Yanting;  Ma, Xiuli;  Kong, Qinghua;  Xu, Yuhui;  Hu, Jing;  Wang, Fang;  Qin, Wanying;  Wang, Libin;  Xiong, Wenyong
浏览  |  Adobe PDF(1287Kb)  |  收藏  |  浏览/下载：243/58  |  提交时间：2019/03/18
GLUT4  pHluorin  Screening  Glucose uptake  
12th全国天然有机化学学术会议摘要集 会议录
会议录编者:  中国化学会
Adobe PDF(123481Kb)  |  收藏  |  浏览/下载：187/8  |  提交时间：2018/10/24
Effects of indole alkaloids from leaf of Alstonia scholaris on post-infectious cough in mice 期刊论文
Journal of Ethnopharmacology, 2018, 卷号: 218, 页码: 69–75
作者:  Yun-Li Zhao;  Zi-Feng Yang;  Jian-Hua Shang;   Wan-Yi Huang;   Bei Wang;  Xin Wei;  Afsar Khan;  Zhi-Wei Yuan;  Ya-Ping Liu;  Yi-Fen Wang;  Xin-Hua Wang;  Xiao-Dong Luo
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Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 8, 页码: 2319-2327
作者:  Xu, Yuhui;  Niu, Yanfen;  Gao, Yuan;  Wang, Fang;  Qin, Wanying;  Lu, Yanting;  Hu, Jing;  Peng, Li;  Liu, Jikai;  Xiong, Wenyong
浏览  |  Adobe PDF(4940Kb)  |  收藏  |  浏览/下载：375/61  |  提交时间：2017/10/23
Insulin-resistance  Tuberculata Beumee  Metabolic Syndrome  Srebp  Liver  Cholesterol  Constituents  Homeostasis  Inhibition  Receptors  
Modulation of glucose metabolism by a natural compound from Chloranthus japonicus via activation of AMP-activated protein kinase 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 778
作者:  Hu, Rongkuan;  Yan, Huan;  Fei, Xiaoyan;  Liu, Haiyang;  Wu, Jiarui
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In vitro assessment of the glucose-lowering effects of berberrubine-9-O-beta-D-glucuronide, an active metabolite of berberrubine 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 3, 页码: 351-361
作者:  Yang, Na;  Sun, Run-Bin;  Chen, Xing-Long;  Zhen, Le;  Ge, Chun;  Zhao, Yu-Qing;  He, Jun;  Geng, Jian-Liang;  Guo, Jia-Hua;  Yu, Xiao-Yi;  Fei, Fei;  Feng, Si-Qi;  Zhu, Xuan-Xuan;  Wang, Hong-Bo;  Fu, Feng-Hua;  Aa, Ji-Ye;  Wang, Guang-Ji
浏览  |  Adobe PDF(4661Kb)  |  收藏  |  浏览/下载：271/90  |  提交时间：2017/05/19
Hyperglycemia  Glucose-lowering Effect  Berberine  Berberrubine  Glucuronide  Alpha-glycosidase  Hfd-induced Hyperglycemia Model Of C57bl/6 Mice  Human Normal Liver Cell Line L-o2  Pharmacokinetics  
Current Perspective in the Discovery of Anti-aging Agents from Natural Products. 期刊论文
Natural products and bioprospecting, 2017, 卷号: 7, 期号: 5, 页码: 335-404
作者:  Ding, Ai-Jun;  Zheng, Shan-Qing;  Huang, Xiao-Bing;  Xing, Ti-Kun;  Wu, Gui-Sheng;  Sun, Hua-Ying;  Qi, Shu-Hua;  Luo, Huai-Rong
浏览  |  Adobe PDF(10117Kb)  |  收藏  |  浏览/下载：133/27  |  提交时间：2019/03/29
Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2016, 卷号: 116, 页码: 39-50
作者:  Zhou, Hongyu;  Shang, Chaowei;  Wang, Min;  Shen, Tao;  Kong, Lingmei;  Yu, Chunlei;  Ye, Zhennan;  Luo, Yan;  Liu, Lei;  Li, Yan;  Huang, Shile
浏览  |  Adobe PDF(3794Kb)  |  收藏  |  浏览/下载：188/40  |  提交时间：2017/01/05
Ciclopirox  Mtor  Ampk  Tsc2  Raptor