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Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：312/37  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
一种HCV抑制剂中间体9-羟基-6-氧-4-甲基菲啶的全合成 期刊论文
云南民族大学学报(自然科学版), 2016, 期号: 6, 页码: 499-502
作者:  杨碧娟;  刘广锦;  郭晶晶;  景晨旭;  陈铎之;  郝小江
浏览  |  Adobe PDF(223Kb)  |  收藏  |  浏览/下载：394/96  |  提交时间：2016/12/19
全合成  9-羟基-6-氧-4-甲基菲啶  钯催化烷基-烷基  N-芳基一步偶联  
Design, Synthesis, and Structural Optimization of Lycorine-Derived Phenanthridine Derivatives as Wnt/beta-Catenin Signaling Pathway Agonists 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 1, 页码: 180-188
作者:  Chen, Duo-Zhi;  Jing, Chen-Xu;  Cai, Jie-Yun;  Wu, Ji-Bo;  Wang, Sheng;  Yin, Jun -Lin;  Li, Xiao-Nian;  Li, Lin;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3043Kb)  |  收藏  |  浏览/下载：312/73  |  提交时间：2016/06/27
Design, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Chen,Duozhi;  Cai,Jieyun;  Cheng,Junjun;  Jing,Chenxu;  Yin,Junlin;  Jiang,Jiandong;  Peng,Zonggen;  Hao,Xiaojiang
浏览  |  Adobe PDF(833Kb)  |  收藏  |  浏览/下载：210/77  |  提交时间：2016/01/19
Lycorine-derived phenanthridine downregulators of host Hsc70 as potential hepatitis C virus inhibitors 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2015, 卷号: 7, 期号: 5, 页码: 561-570
作者:  Chen, Duozhi;  Cai, Jieyun;  Yin, Junlin;  Jiang, Jiandong;  Jing, Chenxu;  Zhu, Yanping;  Cheng, Junjun;  Di, Yingtong;  Zhang, Yu;  Cao, Mingming;  Li, Shunlin;  Peng, Zonggen;  Hao, Xiaojiang;  Hao,XJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  haoxj@mail.kib.ac.cn
浏览  |  Adobe PDF(1560Kb)  |  收藏  |  浏览/下载：291/54  |  提交时间：2015/07/20
Design, Synthesis and Biological Evaluation of Caudatin Analogs as Potent Hepatitis B Virus Inhibitors 期刊论文
MEDICINAL CHEMISTRY, 2015, 卷号: 11, 期号: 2, 页码: 165-179
作者:  Wang, Li-Jun;  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Chen,JJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.
浏览  |  Adobe PDF(375Kb)  |  收藏  |  浏览/下载：208/71  |  提交时间：2015/06/29
Anti-hbv Activity  Caudatin Analogs  Hepatitis b e Antigen (Hbeag)  Hepatitis b Surface Antigen (Hbsag)  Hbv Dna Replication  Structure-activity Relationships(Sars)  Synthesis  
Evaluation of anti-HCV activity and SAR study of (+)-lycoricidine through targeting of host heat-stress cognate 70 (Hsc70) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 9, 页码: 2679-2682
作者:  Chen, Duo-Zhi;  Jiang, Jian-Dong;  Zhang, Ke-Qing;  He, Hong-Ping;  Di, Ying-Tong;  Zhang, Yu;  Cai, Jie-Yun;  Wang, Lei;  Li, Shun-Lin;  Yi, Ping;  Peng, Zong-Gen;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(555Kb)  |  收藏  |  浏览/下载：510/105  |  提交时间：2013/06/08
(+)-lycoricidine  Heat-stress Cognate 70 (Hsc70)  Down-regulators  Structure-activity Relationship (Sar)  Anti-hcv Activity  
Design, synthesis, and molecular hybrids of caudatin and cinnamic acids as novel anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 54, 页码: 352-365
作者:  Wang, Li-Jun;  Geng, Chang-An;  Ma, Yun-Bao;  Luo, Jie;  Huang, Xiao-Yan;  Chen, Hao;  Zhou, Ning-Jia;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(719Kb)  |  收藏  |  浏览/下载：433/138  |  提交时间：2012/11/30
Synthesis  Molecular Hybrids  Caudatin Derivatives  Anti-hepatitis b Virus  Unique Mechanisms