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Design and synthesis of ludartin derivatives as potential anticancer agents against hepatocellular carcinoma 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 7, 页码: 1224-1239
作者:  Sun, Jin-Jin;  Wang, Jin-Ping;  Li, Tian-Ze;  Ma, Yun-Bao;  Xue, Dong;  Chen, Ji-Jun
Adobe PDF(1092Kb)  |  收藏  |  浏览/下载：16/3  |  提交时间：2024/04/30
Ludartin derivatives  Antihepatoma activity  HepG2 cells  Huh7 cells  SESQUITERPENE LACTONES  CHEMICAL-CONSTITUENTS  GUAIANOLIDES  ANTITUMOR  ANALOGS  
New guaiane-type sesquiterpenoid dimers from Artemisia atrovirens and their antihepatoma activity 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 6, 页码: 1648-1666
作者:  Su,Lihua;  Zhang,Xintian;  Ma,Yunbao;  Geng,Changan;  Huang,Xiaoyan;  Hu,Jing;  Li,Tianze;  Tang,Shuang;  Shen,Cheng;  Gao,Zhen;  Zhang,Xuemei;  Chen,Ji-Jun
Adobe PDF(4074Kb)  |  收藏  |  浏览/下载：94/35  |  提交时间：2022/04/02
Guaianolide dimers  Artematrolides AeR  Artemisia atrovirens  Cytotoxicity  Cell cycle  Apoptosis  FARNESYL-PROTEIN TRANSFERASE  CELL-CYCLE ARREST  HEPATOCELLULAR-CARCINOMA  GUAIANOLIDES  LACTONES  INHIBITORS  ARTEMINOLIDE  APOPTOSIS  ARGYI  HELA  
Artematrolide A inhibited cervical cancer cell proliferation via ROS/ERK/mTOR pathway and metabolic shift 期刊论文
PHYTOMEDICINE, 2021, 卷号: 91, 页码: 153707
作者:  Zhang,Xin-Tian;  Hu,Jing;  Su,Li-Hua;  Geng,Chang-An;  Chen,Ji-Jun
Adobe PDF(6313Kb)  |  收藏  |  浏览/下载：102/31  |  提交时间：2022/04/02
Artemisia atrovirens  Cervical cancer  ERK pathway  Cell metabolism  ALKALINE-PHOSPHATASE  SIGNALING PATHWAY  DIFFERENTIATION  APOPTOSIS  ERK  MECHANISMS  
Artemicapillasins A-N, cytotoxic coumaric acid analogues against hepatic stellate cell LX2 from Artemisia capillaris (Yin-Chen) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 117, 页码: 105441
作者:  Gao,Zhen;  Huang,Xiao-Yan;  Geng,Chang-An;  Li,Tian-Ze;  Chen,Ji-Jun
Adobe PDF(1872Kb)  |  收藏  |  浏览/下载：115/33  |  提交时间：2022/04/02
Artemisia capillaris  Coumaric acid analogues  Antihepatic fibrosis effects  HSC-LX2  Extracellular matrix  TRADITIONAL CHINESE HERB  ACTIVE CONSTITUENTS  LIVER FIBROSIS  
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Huang,Xiao-Yan;  Zhang,Xue-Mei;  Guo,Yuan-Qiang;  Geng,Chang-An
Adobe PDF(2762Kb)  |  收藏  |  浏览/下载：135/57  |  提交时间：2022/04/02
Alpinia katsumadai  Katsumadainols B-1-B-15  Natural products  Structure elucidation  Biological activity  TYROSINE-PHOSPHATASE 1B  GLYCOGEN-PHOSPHORYLASE  ALPHA-GLUCOSIDASE  ABSOLUTE-CONFIGURATION  STRUCTURE ELUCIDATION  DUAL INHIBITION  SEEDS  CONSTITUENT  DERIVATIVES  CHALCONE  
Chemical profiling and antidiabetic potency of Paeonia delavayi: Comparison between different parts and constituents 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 113998
作者:  Huang,Qian;  Chen,Ji-Jun;  Pan,Yang;  He,Xiao-Feng;  Wang,Yuan;  Zhang,Xue-Mei;  Geng,Chang-An
Adobe PDF(2388Kb)  |  收藏  |  浏览/下载：59/7  |  提交时间：2022/04/02
Paeonia delavayi  Chemical comparison  LCMS analyses  Antidiabetic effects  PTP1B/TCPTP selective inhibitors  LIQUID-CHROMATOGRAPHY  MULTIPLE CONSTITUENTS  RAPID IDENTIFICATION  GLYCOSIDES  ROOT  DERIVATIVES  TARGETS  CAPSULE  L.  
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
Adobe PDF(5184Kb)  |  收藏  |  浏览/下载：89/24  |  提交时间：2022/04/02
Amomum tsao-ko  Amomutsaokins A-H  Flavanol-menthane conjugates  PTP1B selective inhibitors  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  TANNINS  CREVOST  ACID  
Synthesis and anti-fibrotic effects of santamarin derivatives as cytotoxic agents against hepatic stellate cell line LX2 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 41, 页码: 127994
作者:  Wang,Jin-Ping;  Li,Tian-Ze;  Huang,Xiao-Yan;  Geng,Chang-An;  Shen,Cheng;  Sun,Jin-Jin;  Xue,Dong;  Chen,Ji-Jun
Adobe PDF(567Kb)  |  收藏  |  浏览/下载：84/28  |  提交时间：2022/04/02
Santamarin derivatives  Anti-fibrotic effects  HSC-LX2  Extracellular matrix  NF-KAPPA-B  SESQUITERPENE LACTONES  LIVER FIBROSIS  STRUCTURE REQUIREMENT  BAY LEAF  ACTIVATION  
Artemyrianolides A-S, Cytotoxic Sesquiterpenoids from Artemisia myriantha 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2020
作者:  Tang, Shuang;  Zhang, Xin-Tian;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Li, Tian-Ze;  Zhang, Xue-Mei;  Shen, Cheng;  Su, Li-Hua;  Gao, Zhen;  Chen, Ji-Jun
Adobe PDF(2674Kb)  |  收藏  |  浏览/下载：241/67  |  提交时间：2021/01/05
Abietane Diterpenoids with Antioxidative Damage Activity from Rosmarinus officinalis 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020
作者:  Chen, Xing-Long;  Luo, Qing-Yi;  Hu, Wei-Yan;  Chen, Ji-Jun;  Zhang, Rong-Ping
Adobe PDF(1537Kb)  |  收藏  |  浏览/下载：126/28  |  提交时间：2021/01/05