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Metabolic profiling of coumarins by the combination of UPLC-MS-based metabolomics and multiple mass defect filter 期刊论文
XENOBIOTICA, 2020
作者:  Xiao, Yao;  Wang, Yi-Kun;  Xiao, Xue-Rong;  Zhao, Qi;  Huang, Jian-Feng;  Zhu, Wei-Feng;  Li, Fei
Adobe PDF(1541Kb)  |  收藏  |  浏览/下载：114/44  |  提交时间：2021/01/05
Celastrol ameliorates acute liver injury through modulation of PPAR alpha 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020
作者:  Zhao, Qi;  Tang, Ping;  Zhang, Ting;  Huang, Jian-Feng;  Xiao, Xue-Rong;  Zhu, Wei-Feng;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(6195Kb)  |  收藏  |  浏览/下载：91/19  |  提交时间：2021/01/05
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
作者:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(1740Kb)  |  收藏  |  浏览/下载：200/22  |  提交时间：2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
作者:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(3915Kb)  |  收藏  |  浏览/下载：225/40  |  提交时间：2019/07/29
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(1101Kb)  |  收藏  |  浏览/下载：240/104  |  提交时间：2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling 期刊论文
MOLECULAR & CELLULAR PROTEOMICS, 2019, 卷号: 18, 期号: 3, 页码: 520-533
作者:  Zhao, Qi;  Liu, Fang;  Cheng, Yan;  Xiao, Xue-Rong;  Hu, Dan-Dan;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(4782Kb)  |  收藏  |  浏览/下载：167/58  |  提交时间：2019/07/29
Modulation of Lipid Metabolism by Celastrol 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 1133-1144
作者:  Zhang, Ting;  Zhao, Qi;  Xiao, Xuerong;  Yang, Rui;  Hu, Dandan;  Zhu, Xu;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(5774Kb)  |  收藏  |  浏览/下载：302/63  |  提交时间：2019/04/15
celastrol  lipidomics  hyperlipidemia  LC-MS  
Metabolomic analysis of cholestatic liver damage in mice 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2018, 卷号: 120, 页码: 253-260
作者:  Yang, Rui;  Zhao, Qi;  Hu, Dan-Dan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Li, Fei
收藏  |  浏览/下载：104/0  |  提交时间：2018/11/12
Cholestatic liver damage  PBC  PSC  Metabolomics  QTOFMS  
Metabolic map of osthole and its effect on lipids 期刊论文
XENOBIOTICA, 2018, 卷号: 48, 期号: 3, 页码: 285-299
作者:  Zhao, Qi;  Li, Xin-Mei;  Liu, Hong-Ning;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(2482Kb)  |  收藏  |  浏览/下载：224/59  |  提交时间：2017/11/17
Lipid  Metabolomics  Metabolic Disease  Osthole  Time-of-flight Mass Spectrometry  Ultra-performance Liquid Chromatography  
PPAR alpha activation protects against cholestatic liver injury 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 9967
作者:  Zhao, Qi;  Yang, Rui;  Wang, Jing;  Hu, Dan-Dan;  Li, Fei
Adobe PDF(7693Kb)  |  收藏  |  浏览/下载：230/51  |  提交时间：2017/10/23
Primary Biliary-cirrhosis  Bile-acid Homeostasis  Receptor-alpha  Ursodeoxycholic Acid  Cholesterol 7-alpha-hydroxylase  Beta-oxidation  Fenofibrate  Therapy  Mice  Hepatotoxicity