Metabolic map of osthole and its effect on lipids
Zhao, Qi1,2,3; Li, Xin-Mei1,2; Liu, Hong-Ning4; Gonzalez, Frank J.5; Li, Fei1,2
2018
Source PublicationXENOBIOTICA
ISSN0049-8254
Volume48Issue:3Pages:285-299
Abstract1. Osthole, a coumarin compound from plants, is a promising agent for the treatment of metabolic diseases, including hyperglycemia, fatty liver, and cancers. Studies indicate that the peroxisome proliferator-activated receptors (PPAR) alpha and gamma are involved in the pharmacological effects of osthole. The in vitro and in vivo metabolism of osthole and its biological activity are not completely understood.
KeywordLipid Metabolomics Metabolic Disease Osthole Time-of-flight Mass Spectrometry Ultra-performance Liquid Chromatography
DOI10.1080/00498254.2017.1306660
Indexed BySCI
Language英语
WOS IDWOS:000426958800008
Citation statistics
Cited Times:14[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/54985
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China
2.Yunnan Key Lab Nat Med Chem, Kunming, Yunnan, Peoples R China
3.Univ Chinese Acad Sci, Beijing, Peoples R China
4.Jiangxi Univ Tradit Chinese Med, Res Ctr Differentiat & Dev Basic Theory Tradit Ch, Nanchang, Jiangxi, Peoples R China
5.NCI, Lab Metab, Ctr Canc Res, NIH, Bethesda, MD 20892 USA
Recommended Citation
GB/T 7714
Zhao, Qi,Li, Xin-Mei,Liu, Hong-Ning,et al. Metabolic map of osthole and its effect on lipids[J]. XENOBIOTICA,2018,48(3):285-299.
APA Zhao, Qi,Li, Xin-Mei,Liu, Hong-Ning,Gonzalez, Frank J.,&Li, Fei.(2018).Metabolic map of osthole and its effect on lipids.XENOBIOTICA,48(3),285-299.
MLA Zhao, Qi,et al."Metabolic map of osthole and its effect on lipids".XENOBIOTICA 48.3(2018):285-299.
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